STRINGSTRING
PLCG2 PLCG2 LOC105517114 LOC105517114 LOC105509542 LOC105509542 LOC105516879 LOC105516879 PTPRJ PTPRJ FYB1 FYB1 LOC105515808 LOC105515808 LOC105501360 LOC105501360 VASP VASP ENSCANP00000004759 ENSCANP00000004759 WAS WAS MAP3K7 MAP3K7 CHUK CHUK PSMD6 PSMD6 PSMB11 PSMB11 GRAP2 GRAP2 PGBD4 PGBD4 ENSCANP00000006295 ENSCANP00000006295 LOC105508356 LOC105508356 PAK1 PAK1 ENSCANP00000007099 ENSCANP00000007099 NFKBIA NFKBIA PSMA6 PSMA6 ENSCANP00000007912 ENSCANP00000007912 PSMB2 PSMB2 LOC105501361 LOC105501361 PRKCQ PRKCQ ENSCANP00000008806 ENSCANP00000008806 PSMD5 PSMD5 CUL1 CUL1 ENSCANP00000010057 ENSCANP00000010057 PAG1 PAG1 PTEN PTEN UBE2D1 UBE2D1 CSK CSK ENSCANP00000010775 ENSCANP00000010775 IKBKB IKBKB BCL10 BCL10 PSMB7 PSMB7 RPS27A RPS27A PSME3 PSME3 ENSCANP00000000468 ENSCANP00000000468 ENSCANP00000000485 ENSCANP00000000485 LOC105513286 LOC105513286 LOC105521899 LOC105521899 LOC105501700 LOC105501700 PSMD8 PSMD8 PSMD11 PSMD11 PAK3 PAK3 ENSCANP00000025746 ENSCANP00000025746 CARD11 CARD11 ENSCANP00000025859 ENSCANP00000025859 ENSCANP00000026188 ENSCANP00000026188 TAB2 TAB2 PSMB8 PSMB8 LOC105520594 LOC105520594 PSMF1 PSMF1 PSMB1 PSMB1 SKP1 SKP1 LOC105525747 LOC105525747 SPNS1 SPNS1 UBE2NL UBE2NL LOC105521476 LOC105521476 PSMA2 PSMA2 LOC105520745 LOC105520745 LOC105500584 LOC105500584 CD3D CD3D PIK3CB PIK3CB PSME4 PSME4 PTPN22 PTPN22 ENSCANP00000030491 ENSCANP00000030491 PAK2 PAK2 PSMB4 PSMB4 RIPK2 RIPK2 FBXW11 FBXW11 LOC105501359 LOC105501359 PSMD4 PSMD4 ITK ITK PSMA3 PSMA3 PIK3R2 PIK3R2 PSMD7 PSMD7 ENSCANP00000032549 ENSCANP00000032549 PSMC2 PSMC2 CDC34 CDC34 NCK1 NCK1 RELA RELA INPP5D INPP5D LOC105504558 LOC105504558 CD3G CD3G ENSCANP00000033944 ENSCANP00000033944 PSMB9 PSMB9 ENSCANP00000036083 ENSCANP00000036083 IKBKG IKBKG CD4 CD4 CD3E CD3E PSMB5 PSMB5 PSMD14 PSMD14 PSMC5 PSMC5 ZAP70 ZAP70 LCK LCK PSMD13 PSMD13 LAT LAT PSMD9 PSMD9 PSMD3 PSMD3 BTRC BTRC PSMA1 PSMA1 UBA52 UBA52 PSME2 PSME2 ENSCANP00000011827 ENSCANP00000011827 LOC105523183 LOC105523183 PLCG1 PLCG1 ENAH ENAH UBE2D2 UBE2D2 PSMA4 PSMA4 PSMA5 PSMA5 ENSCANP00000013611 ENSCANP00000013611 PSMD12 PSMD12 PSMB6 PSMB6 CCDC71L CCDC71L PSMC6 PSMC6 HLA-DRA HLA-DRA LOC105518935 LOC105518935 PSMA8 PSMA8 PSMA7 PSMA7 CD247 CD247 PTPRC PTPRC LOC105502761 LOC105502761 LOC105514240 LOC105514240 PSMB10 PSMB10 PSME1 PSME1 LOC105503496 LOC105503496 MAP3K20 MAP3K20 ENSCANP00000016508 ENSCANP00000016508 PIK3CA PIK3CA ENSCANP00000017387 ENSCANP00000017387 LOC105520631 LOC105520631 TRAF6 TRAF6 PSMD2 PSMD2 HLA-DQB1 HLA-DQB1 ENSCANP00000018891 ENSCANP00000018891 PSMC3 PSMC3 PSMC4 PSMC4 ENSCANP00000019642 ENSCANP00000019642 TRAT1 TRAT1 LOC105513801 LOC105513801 SPNS3 SPNS3 ENSCANP00000020516 ENSCANP00000020516 UBE2N UBE2N PSMD10 PSMD10 CD101 CD101 HLA-DRB5 HLA-DRB5 MALT1 MALT1 PSMD1 PSMD1 TRAV29DV5 TRAV29DV5 PIK3R1 PIK3R1 TRAC TRAC ENSCANP00000022288 ENSCANP00000022288 EVL EVL LOC105513786 LOC105513786 PDPK1 PDPK1 LCP2 LCP2 ENSCANP00000023943 ENSCANP00000023943 NFKB1 NFKB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1257 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
LOC105509542UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC105516879Proteasome endopeptidase complex. (214 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1295 aa)
FYB1FYN binding protein 1. (838 aa)
LOC105515808UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
LOC105501360Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (380 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
WASWASP actin nucleation promoting factor. (504 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
PSMB11Proteasome subunit beta. (300 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
PGBD4PiggyBac transposable element derived 4. (585 aa)
ENSCANP00000006295ANK_REP_REGION domain-containing protein. (151 aa)
LOC105508356PCI domain-containing protein. (411 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
ENSCANP00000007099Uncharacterized protein. (213 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
PSMB2Proteasome subunit beta. (201 aa)
LOC105501361Ig-like domain-containing protein. (296 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
ENSCANP00000008806Uncharacterized protein. (357 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
ENSCANP00000010057AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (432 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
CSKTyrosine-protein kinase. (450 aa)
ENSCANP00000010775ATPase_AAA_core domain-containing protein. (385 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
PSMB7Proteasome subunit beta. (277 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSME3Proteasome activator subunit 3. (170 aa)
ENSCANP00000000468ATPase_AAA_core domain-containing protein. (421 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
LOC105513286UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
LOC105501700UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (410 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
ENSCANP00000025746Uncharacterized protein; Belongs to the SKP1 family. (167 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
ENSCANP00000025859UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa)
ENSCANP00000026188AAA domain-containing protein; Belongs to the AAA ATPase family. (430 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
PSMB8Proteasome subunit beta. (284 aa)
LOC105520594AAA domain-containing protein; Belongs to the AAA ATPase family. (442 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMB1Proteasome subunit beta. (241 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa)
LOC105525747UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
SPNS1Sphingolipid transporter 1 (putative). (455 aa)
UBE2NLUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
LOC10552147626S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (834 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
LOC105520745AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
LOC105500584Uncharacterized protein. (180 aa)
CD3DCD3d molecule. (171 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
PSME4Proteasome activator subunit 4. (1844 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (813 aa)
ENSCANP00000030491WH1 domain-containing protein. (137 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
FBXW11F-box and WD repeat domain containing 11. (542 aa)
LOC105501359Ig-like domain-containing protein. (281 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (380 aa)
ITKTyrosine-protein kinase. (620 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PIK3R2Uncharacterized protein. (601 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
ENSCANP00000032549AAA_lid_3 domain-containing protein. (354 aa)
PSMC2AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
CDC34Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family. (236 aa)
NCK1Cytoplasmic protein. (377 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1211 aa)
LOC105504558UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa)
CD3GCD3g molecule. (181 aa)
ENSCANP00000033944Uncharacterized protein; Belongs to the SKP1 family. (131 aa)
PSMB9Proteasome subunit beta 9. (177 aa)
ENSCANP00000036083Uncharacterized protein. (111 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (369 aa)
CD4CD4 molecule. (458 aa)
CD3ECD3e molecule. (198 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
LCKTyrosine-protein kinase. (539 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (399 aa)
LATLinker for activation of T cells. (254 aa)
PSMD9PDZ domain-containing protein. (223 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (527 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PSME2Proteasome activator subunit 2. (255 aa)
ENSCANP00000011827Uncharacterized protein. (106 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
ENAHENAH actin regulator. (790 aa)
UBE2D2UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ENSCANP00000013611AAA domain-containing protein. (371 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMB6Proteasome subunit beta. (245 aa)
CCDC71LUncharacterized protein. (307 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
LOC105518935AAA domain-containing protein; Belongs to the AAA ATPase family. (426 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSMA7Proteasome endopeptidase complex. (178 aa)
CD247CD247 molecule. (163 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1311 aa)
LOC105502761Ig-like domain-containing protein. (283 aa)
LOC105514240Ig-like domain-containing protein. (256 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSME1Proteasome activator subunit 1. (247 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
ENSCANP00000016508JAB_MPN domain-containing protein. (167 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSCANP00000017387Proteasome subunit beta. (181 aa)
LOC105520631UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (747 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (269 aa)
ENSCANP00000018891Uncharacterized protein; Belongs to the SKP1 family. (137 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
TRAT1T cell receptor associated transmembrane adaptor 1. (187 aa)
LOC105513801Ig-like domain-containing protein. (279 aa)
SPNS3Sphingolipid transporter 3 (putative). (490 aa)
ENSCANP00000020516CSN8_PSD8_EIF3K domain-containing protein. (254 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
CD101CD101 molecule. (1021 aa)
HLA-DRB5Major histocompatibility complex, class II, DR beta 5. (266 aa)
MALT1MALT1 paracaspase. (778 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
TRAV29DV5T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene). (150 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
TRACT cell receptor alpha constant. (110 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
EVLEnah/Vasp-like. (472 aa)
LOC105513786Ig-like domain-containing protein. (266 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (406 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
ENSCANP00000023943Proteasome subunit beta. (204 aa)
NFKB1Nuclear factor kappa B subunit 1. (970 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
Server load: low (18%) [HD]