54 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FBXW7	F-box and WD repeat domain containing 7. (707 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	HDAC8	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (377 aa)
	HEY1	Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
	RBPJ	Recombination signal binding protein for immunoglobulin kappa J region. (524 aa)
	LOC105517114	Ubiquitin-like domain-containing protein. (156 aa)
	HDAC7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1002 aa)
	LOC105527037	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (459 aa)
	RBX1	Ring-box 1. (108 aa)
	ENSCANP00000003880	Hist_deacetyl domain-containing protein. (281 aa)
	CCNC	Cyclin C; Belongs to the cyclin family. (283 aa)
	MAML2	Mastermind like transcriptional coactivator 2. (1156 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	KAT2A	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	LOC105516286	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (449 aa)
	HDAC5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1125 aa)
	EP300	E1A binding protein p300. (2409 aa)
	MAML1	Mastermind like transcriptional coactivator 1. (924 aa)
	SNW1	SNW domain containing 1. (571 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	NBEA	Neurobeachin. (2903 aa)
	LOC105503496	Ubiquitin-like domain-containing protein. (147 aa)
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1090 aa)
	NCOR1	Nuclear receptor corepressor 1. (2440 aa)
	CDK8	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
	ENSCANP00000018891	Uncharacterized protein; Belongs to the SKP1 family. (137 aa)
	ENSCANP00000019642	Ribosomal_S27 domain-containing protein. (93 aa)
	HEY2	Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
	TLE3	TLE family member 3, transcriptional corepressor. (782 aa)
	NCOR2	Nuclear receptor corepressor 2. (2510 aa)
	HES1	Hes family bHLH transcription factor 1. (253 aa)
	TBL1X	Transducin beta like 1 X-linked. (575 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
	TBL1XR1	Transducin beta like 1 X-linked receptor 1. (514 aa)
	MAMLD1	Mastermind like domain containing 1. (990 aa)
	ENSCANP00000025746	Uncharacterized protein; Belongs to the SKP1 family. (167 aa)
	HDAC10	Histone deacetylase 10. (671 aa)
	NOTCH1	Notch receptor 1. (2559 aa)
	TLE1	TLE family member 1, transcriptional corepressor. (770 aa)
	HDAC6	Histone deacetylase 6. (1217 aa)
	HDAC9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (827 aa)
	TLE4	TLE family member 4, transcriptional corepressor. (790 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (476 aa)
	CREBBP	CREB binding protein. (2117 aa)
	HDAC11	Histone deacetylase 11. (359 aa)
	HEYL	Hes related family bHLH transcription factor with YRPW motif like. (328 aa)
	LRBA	LPS responsive beige-like anchor protein. (2852 aa)
	ENSCANP00000033944	Uncharacterized protein; Belongs to the SKP1 family. (131 aa)
	TLE2	TLE family member 2, transcriptional corepressor. (653 aa)
	KAT2B	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (778 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNC	CDK8	ENSCANP00000006026	ENSCANP00000018176	Cyclin C; Belongs to the cyclin family.	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	0.997
CDK8	CCNC	ENSCANP00000018176	ENSCANP00000006026	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Cyclin C; Belongs to the cyclin family.	0.997
CREBBP	ENSCANP00000003880	ENSCANP00000030940	ENSCANP00000003880	CREB binding protein.	Hist_deacetyl domain-containing protein.	0.683
CREBBP	ENSCANP00000019642	ENSCANP00000030940	ENSCANP00000019642	CREB binding protein.	Ribosomal_S27 domain-containing protein.	0.411
CREBBP	EP300	ENSCANP00000030940	ENSCANP00000014363	CREB binding protein.	E1A binding protein p300.	0.996
CREBBP	HDAC1	ENSCANP00000030940	ENSCANP00000030160	CREB binding protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.664
CREBBP	HDAC10	ENSCANP00000030940	ENSCANP00000027124	CREB binding protein.	Histone deacetylase 10.	0.471
CREBBP	HDAC11	ENSCANP00000030940	ENSCANP00000031550	CREB binding protein.	Histone deacetylase 11.	0.458
CREBBP	HDAC2	ENSCANP00000030940	ENSCANP00000024997	CREB binding protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.689
CREBBP	HDAC3	ENSCANP00000030940	ENSCANP00000015133	CREB binding protein.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.683
CREBBP	HDAC4	ENSCANP00000030940	ENSCANP00000017248	CREB binding protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.537
CREBBP	HDAC5	ENSCANP00000030940	ENSCANP00000012765	CREB binding protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.532
CREBBP	HDAC6	ENSCANP00000030940	ENSCANP00000028029	CREB binding protein.	Histone deacetylase 6.	0.609
CREBBP	HDAC7	ENSCANP00000030940	ENSCANP00000002854	CREB binding protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.574
CREBBP	HDAC8	ENSCANP00000030940	ENSCANP00000000852	CREB binding protein.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.576
CREBBP	HDAC9	ENSCANP00000030940	ENSCANP00000028106	CREB binding protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.543
CREBBP	HIF1A	ENSCANP00000030940	ENSCANP00000028666	CREB binding protein.	Hypoxia inducible factor 1 subunit alpha.	0.993
CREBBP	KAT2A	ENSCANP00000030940	ENSCANP00000010322	CREB binding protein.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.952
CREBBP	KAT2B	ENSCANP00000030940	ENSCANP00000036859	CREB binding protein.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.979
CREBBP	LOC105503496	ENSCANP00000030940	ENSCANP00000016322	CREB binding protein.	Ubiquitin-like domain-containing protein.	0.411