STRINGSTRING
UBE2I UBE2I CETN2 CETN2 PML PML NUP58 NUP58 NUP98 NUP98 NFATC2IP NFATC2IP RAD52 RAD52 RING1 RING1 CETN3 CETN3 NUP37 NUP37 SEH1L SEH1L PIAS4 PIAS4 ENSCANP00000011556 ENSCANP00000011556 RAD21 RAD21 ENSCANP00000012396 ENSCANP00000012396 ENSCANP00000012397 ENSCANP00000012397 ENSCANP00000012423 ENSCANP00000012423 ENSCANP00000012968 ENSCANP00000012968 ENSCANP00000013426 ENSCANP00000013426 XRCC4 XRCC4 NUP35 NUP35 MAGEE1 MAGEE1 RPA1 RPA1 ENSCANP00000015161 ENSCANP00000015161 LOC105503451 LOC105503451 ENSCANP00000001395 ENSCANP00000001395 SP140 SP140 SCML2 SCML2 PHC3 PHC3 PCGF2 PCGF2 SMC6 SMC6 ENSCANP00000000051 ENSCANP00000000051 SUMO1 SUMO1 NUP214 NUP214 STAG1 STAG1 ENSCANP00000015955 ENSCANP00000015955 ENSCANP00000016230 ENSCANP00000016230 NUP155 NUP155 BRCA1 BRCA1 NSMCE2 NSMCE2 NUP160 NUP160 SP140L SP140L PCOTH PCOTH NUP133 NUP133 RAE1 RAE1 PHC1 PHC1 ENSCANP00000020642 ENSCANP00000020642 NUP153 NUP153 NUP62 NUP62 NUP43 NUP43 NUP50 NUP50 NUP93 NUP93 LOC105502172 LOC105502172 ENSCANP00000021569 ENSCANP00000021569 SMC5 SMC5 BLM BLM AAAS AAAS NSMCE4A NSMCE4A NUP88 NUP88 NUP54 NUP54 NUP62CL NUP62CL SCMH1 SCMH1 RNF168 RNF168 NUP210 NUP210 TDG TDG WRN WRN MAGEB4 MAGEB4 MAGEE2 MAGEE2 MAGEB6B MAGEB6B MEIOB MEIOB NUP107 NUP107 SP110 SP110 SEC13 SEC13 NUP205 NUP205 SCML1 SCML1 SP100 SP100 RNF2 RNF2 ENSCANP00000033343 ENSCANP00000033343 RNF169 RNF169 PIAS2 PIAS2 PHC2 PHC2 PARP1 PARP1 HERC2 HERC2 RANBP2 RANBP2 NDC1 NDC1 TPR TPR ENSCANP00000038703 ENSCANP00000038703 RECQL4 RECQL4 NUP188 NUP188 CBX8 CBX8 MDC1 MDC1 CBX4 CBX4 PIAS1 PIAS1 NUP42 NUP42 KCTD2 KCTD2 CBX2 CBX2 NUP85 NUP85 SHLD1 SHLD1 LOC105527518 LOC105527518 MAGEF1 MAGEF1 XPC XPC SUMO2 SUMO2 ENSCANP00000005159 ENSCANP00000005159 ENSCANP00000004751 ENSCANP00000004751 NSMCE1 NSMCE1 HDAC7 HDAC7 SMC3 SMC3 STAG2 STAG2 SMC1A SMC1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBE2IUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (315 aa)
CETN2Centrin 2. (172 aa)
PMLPromyelocytic leukemia. (882 aa)
NUP58Nucleoporin 58. (553 aa)
NUP98Nucleoporin 98. (1800 aa)
NFATC2IPNuclear factor of activated T cells 2 interacting protein. (416 aa)
RAD52RAD52 homolog, DNA repair protein. (419 aa)
RING1Ring finger protein 1. (406 aa)
CETN3Centrin 3. (191 aa)
NUP37Nucleoporin 37. (326 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (337 aa)
PIAS4Protein inhibitor of activated STAT 4. (510 aa)
ENSCANP00000011556Small ubiquitin-related modifier. (73 aa)
RAD21RAD21 cohesin complex component. (631 aa)
ENSCANP00000012396HECT domain-containing protein. (423 aa)
ENSCANP00000012397Small ubiquitin-related modifier. (89 aa)
ENSCANP00000012423Uncharacterized protein. (107 aa)
ENSCANP00000012968Uncharacterized protein. (533 aa)
ENSCANP00000013426RING-type domain-containing protein. (324 aa)
XRCC4X-ray repair cross complementing 4. (336 aa)
NUP35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (326 aa)
MAGEE1MAGE family member E1. (891 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (574 aa)
ENSCANP00000015161Rad60-SLD domain-containing protein. (94 aa)
LOC105503451Uncharacterized protein. (1176 aa)
ENSCANP00000001395Uncharacterized protein. (61 aa)
SP140SP140 nuclear body protein. (867 aa)
SCML2Scm polycomb group protein like 2. (701 aa)
PHC3Polyhomeotic homolog 3. (983 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
SMC6Uncharacterized protein. (1092 aa)
ENSCANP00000000051Ubiquitin-like domain-containing protein. (62 aa)
SUMO1Small ubiquitin like modifier 1. (120 aa)
NUP214Nucleoporin 214. (2089 aa)
STAG1Stromal antigen 1. (1258 aa)
ENSCANP00000015955Ubiquitin-like domain-containing protein. (115 aa)
ENSCANP00000016230Nup54 domain-containing protein. (119 aa)
NUP155Nucleoporin 155. (1369 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1775 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (246 aa)
NUP160Nucleoporin 160. (1362 aa)
SP140LSP140 nuclear body protein like. (580 aa)
PCOTHPro-X-Gly collagen triple helix like repeat containing. (107 aa)
NUP133Nucleoporin 133. (1146 aa)
RAE1Ribonucleic acid export 1. (368 aa)
PHC1Polyhomeotic homolog 1. (1004 aa)
ENSCANP00000020642Uncharacterized protein. (121 aa)
NUP153Nucleoporin 153. (1442 aa)
NUP62Nucleoporin 62. (335 aa)
NUP43Nucleoporin 43. (380 aa)
NUP50Nucleoporin 50. (467 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (880 aa)
LOC105502172Rad60-SLD domain-containing protein. (72 aa)
ENSCANP00000021569Small ubiquitin-related modifier. (106 aa)
SMC5SMC_N domain-containing protein. (1102 aa)
BLMBLM RecQ like helicase. (1146 aa)
AAASAladin WD repeat nucleoporin. (546 aa)
NSMCE4ANon-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (385 aa)
NUP88Nucleoporin 88. (741 aa)
NUP54Nucleoporin 54. (508 aa)
NUP62CLNucleoporin 62 C-terminal like. (184 aa)
SCMH1Scm polycomb group protein homolog 1. (660 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (571 aa)
NUP210Nucleoporin 210. (1867 aa)
TDGThymine DNA glycosylase. (410 aa)
WRNWRN RecQ like helicase. (1431 aa)
MAGEB4MAGE family member B4. (268 aa)
MAGEE2MAGE family member E2. (523 aa)
MAGEB6BMAGE family member B6B. (407 aa)
MEIOBMeiosis specific with OB-fold. (392 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (820 aa)
SP110SP110 nuclear body protein. (538 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa)
NUP205Nucleoporin 205. (2006 aa)
SCML1Scm polycomb group protein like 1. (302 aa)
SP100SP100 nuclear antigen. (819 aa)
RNF2Ring finger protein 2. (336 aa)
ENSCANP00000033343UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (198 aa)
RNF169Ring finger protein 169. (575 aa)
PIAS2Protein inhibitor of activated STAT 2. (620 aa)
PHC2Polyhomeotic homolog 2. (859 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4683 aa)
RANBP2RAN binding protein 2. (2872 aa)
NDC1NDC1 transmembrane nucleoporin. (674 aa)
TPRTranslocated promoter region, nuclear basket protein. (2363 aa)
ENSCANP00000038703Uncharacterized protein. (89 aa)
RECQL4RecQ like helicase 4. (1154 aa)
NUP188Nucleoporin 188. (1702 aa)
CBX8Chromobox 8. (387 aa)
MDC1Mediator of DNA damage checkpoint 1. (2089 aa)
CBX4Chromobox 4. (613 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
NUP42Nucleoporin 42. (423 aa)
KCTD2Uncharacterized protein. (64 aa)
CBX2Chromobox 2. (500 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (641 aa)
SHLD1Shieldin complex subunit 1. (205 aa)
LOC105527518RING-type domain-containing protein. (326 aa)
MAGEF1MAGE family member F1. (307 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (939 aa)
SUMO2Small ubiquitin-related modifier. (88 aa)
ENSCANP00000005159Ubiquitin-like domain-containing protein. (129 aa)
ENSCANP00000004751Rad21_Rec8 domain-containing protein. (148 aa)
NSMCE1NSE1 homolog, SMC5-SMC6 complex component. (266 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1002 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
STAG2Stromal antigen 2. (1268 aa)
SMC1AStructural maintenance of chromosomes protein. (1283 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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