STRINGSTRING
AGAP1 AGAP1 DOCK1 DOCK1 UNC5A UNC5A ENSCANP00000025796 ENSCANP00000025796 SLIT3 SLIT3 IGDCC4 IGDCC4 NTN1 NTN1 SLIT1 SLIT1 UNC5C UNC5C NTN4 NTN4 WASL WASL UNC5D UNC5D MAPK12 MAPK12 TRPC1 TRPC1 ENSCANP00000013076 ENSCANP00000013076 SIAH1 SIAH1 PLCG1 PLCG1 RGMA RGMA ENSCANP00000011220 ENSCANP00000011220 ENSCANP00000011118 ENSCANP00000011118 MYO10 MYO10 PRKCQ PRKCQ TRPC7 TRPC7 PAK1 PAK1 ABLIM3 ABLIM3 ENSCANP00000005072 ENSCANP00000005072 ROBO1 ROBO1 FYN FYN AGAP2 AGAP2 MAPK10 MAPK10 DSCAML1 DSCAML1 ENSCANP00000002557 ENSCANP00000002557 AGAP3 AGAP3 MAPK11 MAPK11 EZR EZR SLIT2 SLIT2 TRPC5 TRPC5 ABLIM1 ABLIM1 LOC105517741 LOC105517741 TRPC3 TRPC3 TRIO TRIO PITPNA PITPNA NCK1 NCK1 HJV HJV TRPC4 TRPC4 PTPN11 PTPN11 SIAH2 SIAH2 MAPK13 MAPK13 ENSCANP00000034934 ENSCANP00000034934 NEO1 NEO1 DCC DCC ENSCANP00000036145 ENSCANP00000036145 DSCAM DSCAM PTK2 PTK2 UNC5B UNC5B CDC42 CDC42 TRPC6 TRPC6 MAPK14 MAPK14 SRC SRC MAPK8 MAPK8 ABLIM2 ABLIM2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGAP1ArfGAP with GTPase domain, ankyrin repeat and PH domain 1. (829 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1870 aa)
UNC5AUnc-5 netrin receptor A. (899 aa)
ENSCANP00000025796Uncharacterized protein. (269 aa)
SLIT3Slit guidance ligand 3. (1500 aa)
IGDCC4Immunoglobulin superfamily DCC subclass member 4. (1238 aa)
NTN1Netrin 1. (576 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
UNC5CUnc-5 netrin receptor C. (931 aa)
NTN4Netrin 4. (627 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
UNC5DUnc-5 netrin receptor D. (958 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
ENSCANP00000013076Uncharacterized protein. (164 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (458 aa)
ENSCANP00000011220Uncharacterized protein. (277 aa)
ENSCANP00000011118Uncharacterized protein. (176 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2002 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
ABLIM3Actin binding LIM protein family member 3. (690 aa)
ENSCANP00000005072Uncharacterized protein. (168 aa)
ROBO1Roundabout guidance receptor 1. (1598 aa)
FYNTyrosine-protein kinase. (537 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1025 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
DSCAML1DS cell adhesion molecule like 1. (2009 aa)
ENSCANP00000002557Uncharacterized protein. (535 aa)
AGAP3ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (899 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
EZREzrin. (587 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
ABLIM1Actin binding LIM protein 1. (778 aa)
LOC105517741Uncharacterized protein. (611 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (878 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (2689 aa)
PITPNAPhosphatidylinositol transfer protein alpha. (263 aa)
NCK1Cytoplasmic protein. (377 aa)
HJVHemojuvelin BMP co-receptor. (425 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (299 aa)
MAPK13Mitogen-activated protein kinase. (491 aa)
ENSCANP00000034934SH2 domain-containing protein. (183 aa)
NEO1Neogenin 1. (1451 aa)
DCCDCC netrin 1 receptor. (1447 aa)
ENSCANP00000036145Uncharacterized protein. (268 aa)
DSCAMDS cell adhesion molecule. (2010 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
UNC5BUnc-5 netrin receptor B. (945 aa)
CDC42Cell division cycle 42. (191 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SRCTyrosine-protein kinase. (458 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ABLIM2Actin binding LIM protein family member 2. (660 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
Server load: medium (48%) [HD]