61 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRIO	Trio Rho guanine nucleotide exchange factor. (2689 aa)
	LOC105517741	Uncharacterized protein. (611 aa)
	ABLIM1	Actin binding LIM protein 1. (778 aa)
	TRPC5	Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
	SLIT1	Slit guidance ligand 1. (1534 aa)
	IGDCC4	Immunoglobulin superfamily DCC subclass member 4. (1238 aa)
	NTN1	Netrin 1. (576 aa)
	SLIT3	Slit guidance ligand 3. (1500 aa)
	ENSCANP00000025796	Uncharacterized protein. (269 aa)
	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1. (829 aa)
	ABLIM2	Actin binding LIM protein family member 2. (660 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	ENSCANP00000034934	SH2 domain-containing protein. (183 aa)
	NEO1	Neogenin 1. (1451 aa)
	DCC	DCC netrin 1 receptor. (1447 aa)
	ENSCANP00000036145	Uncharacterized protein. (268 aa)
	DSCAM	DS cell adhesion molecule. (2010 aa)
	PTK2	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
	UNC5B	Unc-5 netrin receptor B. (945 aa)
	CDC42	Cell division cycle 42. (191 aa)
	TRPC6	Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	SRC	Tyrosine-protein kinase. (458 aa)
	SLIT2	Slit guidance ligand 2. (1542 aa)
	EZR	Ezrin. (587 aa)
	MAPK10	Mitogen-activated protein kinase. (550 aa)
	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1025 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	ROBO1	Roundabout guidance receptor 1. (1598 aa)
	UNC5A	Unc-5 netrin receptor A. (899 aa)
	DOCK1	Dedicator of cytokinesis 1; Belongs to the DOCK family. (1870 aa)
	UNC5C	Unc-5 netrin receptor C. (931 aa)
	NTN4	Netrin 4. (627 aa)
	WASL	WASP like actin nucleation promoting factor. (505 aa)
	UNC5D	Unc-5 netrin receptor D. (958 aa)
	MAPK12	Mitogen-activated protein kinase. (325 aa)
	TRPC1	Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
	ENSCANP00000013076	Uncharacterized protein. (164 aa)
	SIAH1	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
	RGMA	Repulsive guidance molecule BMP co-receptor a. (458 aa)
	ENSCANP00000011220	Uncharacterized protein. (277 aa)
	ENSCANP00000011118	Uncharacterized protein. (176 aa)
	MYO10	Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2002 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
	TRPC7	Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
	PAK1	Non-specific serine/threonine protein kinase. (555 aa)
	ABLIM3	Actin binding LIM protein family member 3. (690 aa)
	ENSCANP00000005072	Uncharacterized protein. (168 aa)
	DSCAML1	DS cell adhesion molecule like 1. (2009 aa)
	ENSCANP00000002557	Uncharacterized protein. (535 aa)
	AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (899 aa)
	MAPK11	Mitogen-activated protein kinase. (306 aa)
	MAPK13	Mitogen-activated protein kinase. (491 aa)
	SIAH2	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (299 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
	TRPC4	Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
	HJV	Hemojuvelin BMP co-receptor. (425 aa)
	NCK1	Cytoplasmic protein. (377 aa)
	PITPNA	Phosphatidylinositol transfer protein alpha. (263 aa)
	TRPC3	Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (878 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABLIM1	ABLIM2	ENSCANP00000031211	ENSCANP00000023949	Actin binding LIM protein 1.	Actin binding LIM protein family member 2.	0.834
ABLIM1	ABLIM3	ENSCANP00000031211	ENSCANP00000006245	Actin binding LIM protein 1.	Actin binding LIM protein family member 3.	0.829
ABLIM1	CDC42	ENSCANP00000031211	ENSCANP00000037982	Actin binding LIM protein 1.	Cell division cycle 42.	0.489
ABLIM1	ENSCANP00000005072	ENSCANP00000031211	ENSCANP00000005072	Actin binding LIM protein 1.	Uncharacterized protein.	0.489
ABLIM1	ENSCANP00000011118	ENSCANP00000031211	ENSCANP00000011118	Actin binding LIM protein 1.	Uncharacterized protein.	0.489
ABLIM1	ENSCANP00000013076	ENSCANP00000031211	ENSCANP00000013076	Actin binding LIM protein 1.	Uncharacterized protein.	0.489
ABLIM2	ABLIM1	ENSCANP00000023949	ENSCANP00000031211	Actin binding LIM protein family member 2.	Actin binding LIM protein 1.	0.834
ABLIM2	CDC42	ENSCANP00000023949	ENSCANP00000037982	Actin binding LIM protein family member 2.	Cell division cycle 42.	0.489
ABLIM2	ENSCANP00000005072	ENSCANP00000023949	ENSCANP00000005072	Actin binding LIM protein family member 2.	Uncharacterized protein.	0.489
ABLIM2	ENSCANP00000011118	ENSCANP00000023949	ENSCANP00000011118	Actin binding LIM protein family member 2.	Uncharacterized protein.	0.489
ABLIM2	ENSCANP00000013076	ENSCANP00000023949	ENSCANP00000013076	Actin binding LIM protein family member 2.	Uncharacterized protein.	0.489
ABLIM3	ABLIM1	ENSCANP00000006245	ENSCANP00000031211	Actin binding LIM protein family member 3.	Actin binding LIM protein 1.	0.829
ABLIM3	CDC42	ENSCANP00000006245	ENSCANP00000037982	Actin binding LIM protein family member 3.	Cell division cycle 42.	0.536
ABLIM3	ENSCANP00000005072	ENSCANP00000006245	ENSCANP00000005072	Actin binding LIM protein family member 3.	Uncharacterized protein.	0.536
ABLIM3	ENSCANP00000011118	ENSCANP00000006245	ENSCANP00000011118	Actin binding LIM protein family member 3.	Uncharacterized protein.	0.489
ABLIM3	ENSCANP00000013076	ENSCANP00000006245	ENSCANP00000013076	Actin binding LIM protein family member 3.	Uncharacterized protein.	0.536
AGAP1	UNC5B	ENSCANP00000024080	ENSCANP00000037864	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1.	Unc-5 netrin receptor B.	0.500
AGAP2	UNC5B	ENSCANP00000018451	ENSCANP00000037864	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	Unc-5 netrin receptor B.	0.678
AGAP3	UNC5B	ENSCANP00000002364	ENSCANP00000037864	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3.	Unc-5 netrin receptor B.	0.500
CDC42	ABLIM1	ENSCANP00000037982	ENSCANP00000031211	Cell division cycle 42.	Actin binding LIM protein 1.	0.489