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APOB APOB PPP2R5E PPP2R5E GNG5 GNG5 PTGIR PTGIR GUCY1B1 GUCY1B1 ENSCANP00000002519 ENSCANP00000002519 ENSCANP00000002557 ENSCANP00000002557 PDE2A PDE2A ATP2A1 ATP2A1 GNG3 GNG3 ENSCANP00000005529 ENSCANP00000005529 GNGT1 GNGT1 LRP8 LRP8 ATP2B1 ATP2B1 GNG11 GNG11 REEP3 REEP3 PPP2R5D PPP2R5D TRPC7 TRPC7 ATP2B3 ATP2B3 LOC105510963 LOC105510963 PDE5A PDE5A P2RX1 P2RX1 GNG4 GNG4 ENSCANP00000010138 ENSCANP00000010138 GNG13 GNG13 MRVI1 MRVI1 ENSCANP00000011220 ENSCANP00000011220 GNB1 GNB1 KCNMB2 KCNMB2 FGR FGR P2RX5 P2RX5 ENSCANP00000012579 ENSCANP00000012579 GUCY1A2 GUCY1A2 PDE1A PDE1A PDE10A PDE10A P2RX4 P2RX4 ORAI2 ORAI2 SLC8A2 SLC8A2 NOS3 NOS3 P2RX3 P2RX3 KCNMB1 KCNMB1 SRI SRI PDE11A PDE11A PRKG1 PRKG1 GNB4 GNB4 GNB2 GNB2 ATP2B2 ATP2B2 STIM1 STIM1 GNB3 GNB3 ATP2A3 ATP2A3 KCNMA1 KCNMA1 GNG8 GNG8 PLA2G4A PLA2G4A GNAS GNAS PECAM1 PECAM1 ORAI3 ORAI3 PDE9A PDE9A PPP2R5A PPP2R5A SLC8A3 SLC8A3 REEP2 REEP2 PPP2R5C PPP2R5C ITPR3 ITPR3 GNG7 GNG7 ENSCANP00000024087 ENSCANP00000024087 GNG12 GNG12 P2RX6 P2RX6 KCNMB4 KCNMB4 ENSCANP00000025796 ENSCANP00000025796 GNB5 GNB5 NOS1 NOS1 PDE1B PDE1B PTPN6 PTPN6 GNG2 GNG2 PPP2CB PPP2CB ATP2B4 ATP2B4 SLC8A1 SLC8A1 PPP2CA PPP2CA ITPR1 ITPR1 PPP2R1A PPP2R1A ENSCANP00000030030 ENSCANP00000030030 ENSCANP00000031216 ENSCANP00000031216 TRPC3 TRPC3 ATP2A2 ATP2A2 ENSCANP00000032506 ENSCANP00000032506 GNGT2 GNGT2 PTPN11 PTPN11 NOS2 NOS2 ENSCANP00000034934 ENSCANP00000034934 LOC105525710 LOC105525710 PPP2R1B PPP2R1B ENSCANP00000036145 ENSCANP00000036145 GUCY1A1 GUCY1A1 PRKG2 PRKG2 ITPR2 ITPR2 ENSCANP00000037307 ENSCANP00000037307 P2RX2 P2RX2 REEP4 REEP4 ENSCANP00000038043 ENSCANP00000038043 TRPC6 TRPC6 PAFAH2 PAFAH2 P2RX7 P2RX7 MAPK14 MAPK14 PPP2R5B PPP2R5B ORAI1 ORAI1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APOBApolipoprotein B. (4555 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (456 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PTGIRProstaglandin I2 receptor. (386 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (642 aa)
ENSCANP00000002519Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
ENSCANP00000002557Uncharacterized protein. (535 aa)
PDE2APhosphodiesterase. (936 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1027 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ENSCANP00000005529Uncharacterized protein. (134 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
LRP8LDL receptor related protein 8. (880 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
REEP3Receptor expression-enhancing protein. (250 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
LOC105510963Serine/threonine-protein phosphatase. (291 aa)
PDE5APhosphodiesterase. (875 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (375 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ENSCANP00000010138Uncharacterized protein. (68 aa)
GNG13G protein subunit gamma 13. (67 aa)
MRVI1Murine retrovirus integration site 1 homolog. (911 aa)
ENSCANP00000011220Uncharacterized protein. (277 aa)
GNB1G protein subunit beta 1. (203 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
FGRTyrosine-protein kinase. (529 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (357 aa)
ENSCANP00000012579G protein gamma domain-containing protein. (58 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (691 aa)
PDE1APhosphodiesterase. (544 aa)
PDE10APhosphodiesterase. (789 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (383 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (262 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (848 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
SRIUncharacterized protein. (198 aa)
PDE11APhosphodiesterase. (933 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
GNB4G protein subunit beta 4. (291 aa)
GNB2G protein subunit beta 2. (340 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1270 aa)
STIM1Stromal interaction molecule 1. (791 aa)
GNB3G protein subunit beta 3. (340 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1060 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1280 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
PLA2G4APhospholipase A2. (749 aa)
GNASGNAS complex locus. (913 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (646 aa)
ORAI3ORAI calcium release-activated calcium modulator 3. (295 aa)
PDE9APhosphodiesterase. (570 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (480 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
REEP2Receptor expression-enhancing protein. (214 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSCANP00000024087annotation not available (68 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
P2RX6Purinergic receptor P2X 6. (329 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
ENSCANP00000025796Uncharacterized protein. (269 aa)
GNB5G protein subunit beta 5. (393 aa)
NOS1Nitric oxide synthase 1. (1465 aa)
PDE1BPhosphodiesterase. (536 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (613 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (109 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
PPP2CASerine/threonine-protein phosphatase. (275 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2697 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (594 aa)
ENSCANP00000030030Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSCANP00000031216XRCC1_N domain-containing protein. (142 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (878 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (999 aa)
ENSCANP00000032506Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (846 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1181 aa)
ENSCANP00000034934SH2 domain-containing protein. (183 aa)
LOC105525710Uncharacterized protein. (3238 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
ENSCANP00000036145Uncharacterized protein. (268 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
ENSCANP00000037307Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (493 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)
REEP4Receptor expression-enhancing protein. (257 aa)
ENSCANP00000038043Uncharacterized protein. (107 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
PAFAH2Platelet-activating factor acetylhydrolase. (392 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (515 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (238 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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