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| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | LOC105510915 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa) |
| | TM4SF19 | Uncharacterized protein. (209 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | ENSCANP00000020516 | CSN8_PSD8_EIF3K domain-containing protein. (254 aa) |
| | ENSCANP00000007912 | Ubiquitin-like domain-containing protein. (121 aa) |
| | LOC105508356 | PCI domain-containing protein. (411 aa) |
| | ENSCANP00000006295 | ANK_REP_REGION domain-containing protein. (151 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2A. (159 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (442 aa) |
| | LOC105509448 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (245 aa) |
| | ENSCANP00000004759 | Ubiquitin-like domain-containing protein. (147 aa) |
| | RRM2 | Ribonucleotide reductase regulatory subunit M2. (439 aa) |
| | RBBP4 | RB binding protein 4, chromatin remodeling factor. (425 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | RPA2 | Replication protein A2. (273 aa) |
| | ENSCANP00000008806 | Uncharacterized protein. (357 aa) |
| | LIN52 | Lin-52 DREAM MuvB core complex component. (116 aa) |
| | LOC105510963 | Serine/threonine-protein phosphatase. (291 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (470 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (504 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | ENSCANP00000010057 | AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa) |
| | LOC105501639 | WD_REPEATS_REGION domain-containing protein. (398 aa) |
| | ENSCANP00000010775 | ATPase_AAA_core domain-containing protein. (385 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (242 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (301 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | MAX | MYC associated factor X. (152 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa) |
| | E2F5 | E2F transcription factor 5. (343 aa) |
| | FNDC3A | Fibronectin type III domain containing 3A. (1198 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | PPP2R3B | EF-hand domain-containing protein. (176 aa) |
| | LOC105516879 | Proteasome endopeptidase complex. (214 aa) |
| | LOC105527037 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (459 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | CCNB1 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (345 aa) |
| | ENSCANP00000007099 | Uncharacterized protein. (213 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | PSMA6 | Proteasome subunit alpha type. (252 aa) |
| | PSMA7 | Proteasome endopeptidase complex. (178 aa) |
| | PSME2 | Proteasome activator subunit 2. (255 aa) |
| | ENSCANP00000011827 | Uncharacterized protein. (106 aa) |
| | LOC105523183 | Ubiquitin-like domain-containing protein. (77 aa) |
| | LOC105516286 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (449 aa) |
| | FBXO5 | F-box protein 5. (448 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1140 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (509 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (362 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | PSME1 | Proteasome activator subunit 1. (247 aa) |
| | LOC105503496 | Ubiquitin-like domain-containing protein. (147 aa) |
| | ENSCANP00000016508 | JAB_MPN domain-containing protein. (167 aa) |
| | CDC45 | Cell division cycle 45. (598 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1250 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | ENSCANP00000017387 | Proteasome subunit beta. (181 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (747 aa) |
| | ENSCANP00000018891 | Uncharacterized protein; Belongs to the SKP1 family. (137 aa) |
| | PSMC3 | AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | ENSCANP00000019642 | Ribosomal_S27 domain-containing protein. (93 aa) |
| | LOC105507991 | Uncharacterized protein. (869 aa) |
| | TESMIN | Testis expressed metallothionein like protein. (508 aa) |
| | LOC105512501 | WD_REPEATS_REGION domain-containing protein. (396 aa) |
| | TK1 | Thymidine kinase. (275 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) |
| | ORC3 | Origin recognition complex subunit 3. (712 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) |
| | DYRK1A | Dual specificity tyrosine phosphorylation regulated kinase 1A. (762 aa) |
| | FNBP4 | Formin binding protein 4. (950 aa) |
| | WEE2 | Wee1-like protein kinase. (567 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (904 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (116 aa) |
| | ENSCANP00000002755 | WD_REPEATS_REGION domain-containing protein. (343 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (831 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (409 aa) |
| | ENSCANP00000002256 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (86 aa) |
| | LOC105517114 | Ubiquitin-like domain-containing protein. (156 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | MYBL2 | MYB proto-oncogene like 2. (700 aa) |
| | MCM8 | MCM domain-containing protein; Belongs to the MCM family. (762 aa) |
| | LOC105521899 | Ubiquitin-like domain-containing protein. (146 aa) |
| | ENSCANP00000000485 | Ubiquitin-like domain-containing protein. (72 aa) |
| | ENSCANP00000000468 | ATPase_AAA_core domain-containing protein. (421 aa) |
| | PSME3 | Proteasome activator subunit 3. (170 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | CDC25A | Cell division cycle 25A. (501 aa) |
| | DYRK1B | Dual specificity tyrosine phosphorylation regulated kinase 1B. (629 aa) |
| | RBL1 | RB transcriptional corepressor like 1. (959 aa) |
| | SRC | Tyrosine-protein kinase. (458 aa) |
| | CABLES1 | Cdk5 and Abl enzyme substrate 1. (368 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (860 aa) |
| | CDK1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (499 aa) |
| | TFDP1 | Transcription factor. (410 aa) |
| | ENSCANP00000038603 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (409 aa) |
| | E2F3 | E2F transcription factor 3. (381 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2267 aa) |
| | CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (399 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (138 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | TYMS | Thymidylate synthetase. (313 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (854 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (390 aa) |
| | TFDP2 | Transcription factor. (446 aa) |
| | ENSCANP00000036083 | Uncharacterized protein. (111 aa) |
| | FNDC3B | Fibronectin type III domain containing 3B. (1204 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) |
| | PSMB9 | Proteasome subunit beta 9. (177 aa) |
| | PTK6 | Tyrosine-protein kinase. (451 aa) |
| | KIAA2012 | KIAA2012. (1181 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | ORC2 | Origin recognition complex subunit 2. (561 aa) |
| | LIN9 | Lin-9 DREAM MuvB core complex component. (615 aa) |
| | ENSCANP00000034313 | Protein kinase domain-containing protein. (543 aa) |
| | E2F6 | E2F transcription factor 6. (281 aa) |
| | JAK2 | Tyrosine-protein kinase. (1139 aa) |
| | ENSCANP00000033944 | Uncharacterized protein; Belongs to the SKP1 family. (131 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | PSMC2 | AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa) |
| | ENSCANP00000032549 | AAA_lid_3 domain-containing protein. (354 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | ENSCANP00000032089 | Uncharacterized protein. (120 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (380 aa) |
| | DBF4 | DBF4 zinc finger. (674 aa) |
| | LIN37 | Lin-37 DREAM MuvB core complex component. (246 aa) |
| | SKP2 | S-phase kinase associated protein 2. (424 aa) |
| | RB1 | RB transcriptional corepressor 1. (882 aa) |
| | E2F1 | E2F transcription factor 1. (436 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa) |
| | MEIOB | Meiosis specific with OB-fold. (392 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (476 aa) |
| | POLA1 | DNA polymerase. (1474 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (594 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | LOC105500584 | Uncharacterized protein. (180 aa) |
| | LOC105520745 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (275 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | LOC105521476 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (834 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (923 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | ENSCANP00000028184 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (275 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | LOC105520594 | AAA domain-containing protein; Belongs to the AAA ATPase family. (442 aa) |
| | PSMB8 | Proteasome subunit beta. (284 aa) |
| | ENSCANP00000026743 | Transcription factor. (322 aa) |
| | ENSCANP00000026188 | AAA domain-containing protein; Belongs to the AAA ATPase family. (430 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (574 aa) |
| | CDKN1C | Cyclin dependent kinase inhibitor 1C. (288 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa) |
| | LOC105518935 | AAA domain-containing protein; Belongs to the AAA ATPase family. (426 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa) |
| | MCM10 | Minichromosome maintenance 10 replication initiation factor. (853 aa) |
| | ENSCANP00000014026 | Uncharacterized protein. (367 aa) |
| | PSMB6 | Proteasome subunit beta. (245 aa) |
| | PPP2R3A | Protein phosphatase 2 regulatory subunit B''alpha. (1150 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | ENSCANP00000013869 | Thymidylat_synt domain-containing protein. (134 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | ENSCANP00000013611 | AAA domain-containing protein. (371 aa) |
| | CDC7 | Protein kinase domain-containing protein. (574 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | ENSCANP00000013006 | Uncharacterized protein. (122 aa) |
| | GMNN | Geminin DNA replication inhibitor. (209 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (866 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (339 aa) |
| | WEE1 | WEE1 G2 checkpoint kinase. (383 aa) |
| | ENSCANP00000025746 | Uncharacterized protein; Belongs to the SKP1 family. (167 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | E2F4 | E2F transcription factor 4. (370 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (410 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (350 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (749 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | ENSCANP00000024200 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (65 aa) |
| | ENSCANP00000023943 | Proteasome subunit beta. (204 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | ENSCANP00000022785 | Protein kinase domain-containing protein. (322 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa) |
| | CDK7 | Cyclin dependent kinase 7. (309 aa) |
| | ENSCANP00000022288 | Ubiquitin-like domain-containing protein. (79 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1141 aa) |
| | AKT2 | AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa) |
