STRINGSTRING
UBA52 UBA52 NPVF NPVF ENSCANP00000038640 ENSCANP00000038640 TRAF2 TRAF2 FLOT2 FLOT2 XIAP XIAP ENSCANP00000040251 ENSCANP00000040251 LOC105509062 LOC105509062 FAS FAS CDC37 CDC37 IL18 IL18 CASP3 CASP3 RPS27A RPS27A ENSCANP00000000466 ENSCANP00000000466 ENSCANP00000000485 ENSCANP00000000485 LOC105521899 LOC105521899 FLOT1 FLOT1 LOC105521896 LOC105521896 SDCBP SDCBP ENSCANP00000001894 ENSCANP00000001894 LOC105517114 LOC105517114 LOC105516629 LOC105516629 ITCH ITCH LOC105502431 LOC105502431 STUB1 STUB1 CHMP6 CHMP6 ENSCANP00000003898 ENSCANP00000003898 BIRC2 BIRC2 ENSCANP00000004166 ENSCANP00000004166 ENSCANP00000004477 ENSCANP00000004477 BIRC7 BIRC7 TNFSF10 TNFSF10 ENSCANP00000004759 ENSCANP00000004759 PRKN PRKN ENSCANP00000005565 ENSCANP00000005565 ENSCANP00000006223 ENSCANP00000006223 GSDME GSDME ENSCANP00000006850 ENSCANP00000006850 ENSCANP00000007912 ENSCANP00000007912 FASLG FASLG RIPK1 RIPK1 HSP90AA1 HSP90AA1 ENSCANP00000008429 ENSCANP00000008429 LOC105523183 LOC105523183 ENSCANP00000012071 ENSCANP00000012071 CASP8 CASP8 FADD FADD GSDMB GSDMB LOC105500565 LOC105500565 TNFRSF10A TNFRSF10A ENSCANP00000015227 ENSCANP00000015227 CARD18 CARD18 CASP4 CASP4 ENSCANP00000016286 ENSCANP00000016286 LOC105503496 LOC105503496 OGT OGT CASP12 CASP12 TNFRSF10B TNFRSF10B PELI1 PELI1 PDCD6IP PDCD6IP CHMP4C CHMP4C ENSCANP00000019642 ENSCANP00000019642 ELANE ELANE TRADD TRADD CHMP3 CHMP3 BAK1 BAK1 CHMP2B CHMP2B ENSCANP00000022288 ENSCANP00000022288 CARD16 CARD16 NAIP NAIP CHMP2A CHMP2A ENSCANP00000024192 ENSCANP00000024192 CASP1 CASP1 CASP5 CASP5 BIRC3 BIRC3 LOC105525885 LOC105525885 GZMB GZMB CFLAR CFLAR BAX BAX CHMP4B CHMP4B IRF1 IRF1 TP53 TP53 LOC105500957 LOC105500957 UBE2L5 UBE2L5 LOC105515285 LOC105515285 ENSCANP00000030335 ENSCANP00000030335 IL1B IL1B CYCS CYCS RIPK3 RIPK3 CHMP7 CHMP7 IRF2 IRF2 IL1A IL1A HMGB1 HMGB1 MDP1 MDP1 TP63 TP63
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
NPVFNeuropeptide VF precursor. (196 aa)
ENSCANP00000038640Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (96 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (484 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
ENSCANP00000040251Uncharacterized protein; Belongs to the peptidase C14A family. (243 aa)
LOC105509062Uncharacterized protein. (647 aa)
FASFas cell surface death receptor. (331 aa)
CDC37Cell division cycle 37. (378 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
CASP3Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSCANP00000000466Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (372 aa)
LOC105521896Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
SDCBPSyndecan binding protein. (318 aa)
ENSCANP00000001894Uncharacterized protein. (215 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
LOC105516629Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
LOC105502431Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
STUB1STIP1 homology and U-box containing protein 1. (250 aa)
CHMP6Charged multivesicular body protein 6. (221 aa)
ENSCANP00000003898Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
ENSCANP00000004166PDZ domain-containing protein. (294 aa)
ENSCANP00000004477Uncharacterized protein. (192 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
ENSCANP00000005565Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (101 aa)
ENSCANP00000006223Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
GSDMEGasdermin E. (496 aa)
ENSCANP00000006850PDZ domain-containing protein. (282 aa)
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (280 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (625 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (821 aa)
ENSCANP00000008429Uncharacterized protein. (276 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
ENSCANP00000012071Uncharacterized protein. (157 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (538 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (200 aa)
GSDMBGasdermin B. (385 aa)
LOC105500565TPR_REGION domain-containing protein. (1721 aa)
TNFRSF10ATNF receptor superfamily member 10a. (469 aa)
ENSCANP00000015227Uncharacterized protein. (355 aa)
CARD18Caspase recruitment domain family member 18. (91 aa)
CASP4Caspase 4; Belongs to the peptidase C14A family. (377 aa)
ENSCANP00000016286Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (86 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
CASP12Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (336 aa)
TNFRSF10BTNF receptor superfamily member 10b. (444 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
PDCD6IPBRO1 domain-containing protein. (903 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (265 aa)
TRADDTNFRSF1A associated via death domain. (308 aa)
CHMP3Charged multivesicular body protein 3. (221 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
CARD16Caspase recruitment domain family member 16. (197 aa)
NAIPNLR family apoptosis inhibitory protein. (1369 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
ENSCANP00000024192HATPase_c domain-containing protein. (669 aa)
CASP1Caspase 1; Belongs to the peptidase C14A family. (372 aa)
CASP5Caspase 5; Belongs to the peptidase C14A family. (446 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
LOC105525885Uncharacterized protein. (226 aa)
GZMBGranzyme B; Belongs to the peptidase S1 family. (247 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (452 aa)
BAXBCL2 associated X, apoptosis regulator. (198 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
IRF1Interferon regulatory factor. (325 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa)
LOC105500957Uncharacterized protein; Belongs to the peptidase C14A family. (406 aa)
UBE2L5Ubiquitin conjugating enzyme E2 L5; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
LOC105515285HATPase_c domain-containing protein. (711 aa)
ENSCANP00000030335Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (97 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
CYCSCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (518 aa)
CHMP7Charged multivesicular body protein 7. (453 aa)
IRF2Interferon regulatory factor. (349 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (271 aa)
HMGB1Uncharacterized protein. (206 aa)
MDP1Magnesium dependent phosphatase 1. (164 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (654 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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