STRINGSTRING
LOC105502431 LOC105502431 OTULINL OTULINL RPS27A RPS27A SPPL2A SPPL2A TBK1 TBK1 RACK1 RACK1 SPATA2 SPATA2 OTUD7B OTUD7B LOC105503496 LOC105503496 UBE2D4 UBE2D4 CLIP3 CLIP3 CLIP4 CLIP4 USP21 USP21 LOC105505011 LOC105505011 FADD FADD UBE2D2 UBE2D2 CASP8 CASP8 STUB1 STUB1 WDR31 WDR31 NFATC4 NFATC4 USP4 USP4 ENSCANP00000019642 ENSCANP00000019642 TRADD TRADD TAX1BP1 TAX1BP1 TNF TNF CYLD CYLD ENSCANP00000022288 ENSCANP00000022288 ULK2 ULK2 NAIP NAIP TNFRSF1A TNFRSF1A IKBKG IKBKG SPPL2B SPPL2B MADD MADD OPTN OPTN TRAF2 TRAF2 ULK1 ULK1 XIAP XIAP USP2 USP2 BIRC3 BIRC3 RNF31 RNF31 SHARPIN SHARPIN TNFAIP3 TNFAIP3 ENSCANP00000002851 ENSCANP00000002851 BIRC2 BIRC2 BIRC7 BIRC7 ENSCANP00000004759 ENSCANP00000004759 CHUK CHUK TRAF1 TRAF1 MIB2 MIB2 ENSCANP00000007912 ENSCANP00000007912 RIPK1 RIPK1 UBE2D1 UBE2D1 RBCK1 RBCK1 IKBKB IKBKB UBA52 UBA52 LOC105523183 LOC105523183 ENSCANP00000000485 ENSCANP00000000485 LOC105521899 LOC105521899 LOC105517114 LOC105517114 CFLAR CFLAR IKBKE IKBKE ENSCANP00000029020 ENSCANP00000029020 UBE2L5 UBE2L5 LOC105516803 LOC105516803 TMEM198 TMEM198 UBE2D3 UBE2D3 OTULIN OTULIN MAPKAPK2 MAPKAPK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105502431Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
OTULINLOTU deubiquitinase with linear linkage specificity like. (356 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
SPPL2ASignal peptide peptidase like 2A. (461 aa)
TBK1TANK binding kinase 1. (713 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (241 aa)
SPATA2Spermatogenesis associated 2. (520 aa)
OTUD7BOTU deubiquitinase 7B. (843 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
UBE2D4Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
CLIP3CAP-Gly domain containing linker protein 3. (547 aa)
CLIP4CAP-Gly domain containing linker protein family member 4. (705 aa)
USP21Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (565 aa)
LOC105505011WD_REPEATS_REGION domain-containing protein. (312 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (200 aa)
UBE2D2UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (538 aa)
STUB1STIP1 homology and U-box containing protein 1. (250 aa)
WDR31WD repeat domain 31. (367 aa)
NFATC4Nuclear factor of activated T cells 4. (918 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (956 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
TRADDTNFRSF1A associated via death domain. (308 aa)
TAX1BP1Tax1 binding protein 1. (813 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1007 aa)
NAIPNLR family apoptosis inhibitory protein. (1369 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (369 aa)
SPPL2BSignal peptide peptidase like 2B. (538 aa)
MADDMAP kinase activating death domain. (1647 aa)
OPTNOptineurin. (571 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
ULK1Unc-51 like autophagy activating kinase 1. (974 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (576 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
RNF31Uncharacterized protein. (1072 aa)
SHARPINSHANK associated RH domain interactor. (257 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
ENSCANP00000002851UBIQUITIN_CONJUGAT_2 domain-containing protein. (122 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
TRAF1TNF receptor-associated factor. (416 aa)
MIB2Mindbomb E3 ubiquitin protein ligase 2. (939 aa)
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (625 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (452 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (636 aa)
ENSCANP00000029020DUF4203 domain-containing protein. (117 aa)
UBE2L5Ubiquitin conjugating enzyme E2 L5; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
LOC105516803UBIQUITIN_CONJUGAT_2 domain-containing protein. (149 aa)
TMEM198Transmembrane protein 198. (360 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (352 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (431 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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