STRINGSTRING
KCNJ14 KCNJ14 CACNG7 CACNG7 ABCC9 ABCC9 KCNH2 KCNH2 CACNG4 CACNG4 HIPK2 HIPK2 SCN8A SCN8A SCN4B SCN4B SCN3B SCN3B TNNI3 TNNI3 ATP1A3 ATP1A3 MAST1 MAST1 ATP2B3 ATP2B3 NKX2-5 NKX2-5 ATP1A1 ATP1A1 ASPHD2 ASPHD2 FXYD6 FXYD6 ECEL1 ECEL1 ATP1A4 ATP1A4 NOS1 NOS1 FGF11 FGF11 KCND1 KCND1 NPPA NPPA KCNK2 KCNK2 SCN1B SCN1B ATP2B4 ATP2B4 ASPH ASPH MME MME SCN9A SCN9A AKAP9 AKAP9 ORAI1 ORAI1 KCNIP3 KCNIP3 SCN11A SCN11A DMPK DMPK FXYD2 FXYD2 GATA4 GATA4 KCNQ1 KCNQ1 ITPR2 ITPR2 FXYD5 FXYD5 KAT2B KAT2B SCN2B SCN2B FXYD1 FXYD1 FXYD7 FXYD7 CAMK2G CAMK2G KCND2 KCND2 ENSCANP00000034207 ENSCANP00000034207 SCN5A SCN5A NPPC NPPC KCNE4 KCNE4 KCNK7 KCNK7 CACNA1C CACNA1C FGF14 FGF14 ATP2A2 ATP2A2 SCN1A SCN1A KCNK3 KCNK3 KCNK13 KCNK13 MMEL1 MMEL1 KCNIP4 KCNIP4 AHCYL1 AHCYL1 STIM2 STIM2 CORIN CORIN WWTR1 WWTR1 MAST2 MAST2 ITPR1 ITPR1 FXYD3 FXYD3 MAST3 MAST3 ATP2B1 ATP2B1 PHEX PHEX SCN4A SCN4A SLN SLN KCNK5 KCNK5 SLC8A1 SLC8A1 ENSCANP00000005529 ENSCANP00000005529 CACNA2D2 CACNA2D2 KCNJ4 KCNJ4 PLN PLN ATP2A1 ATP2A1 KCNK4 KCNK4 RYR2 RYR2 SCN7A SCN7A LOC105522642 LOC105522642 ASPHD1 ASPHD1 KCNA5 KCNA5 HIPK1 HIPK1 KCNE3 KCNE3 KCNJ11 KCNJ11 ENSCANP00000002603 ENSCANP00000002603 KCNIP2 KCNIP2 CACNB1 CACNB1 ENSCANP00000002281 ENSCANP00000002281 SDR42E2 SDR42E2 ATP1B2 ATP1B2 ENSCANP00000001399 ENSCANP00000001399 KCNJ2 KCNJ2 RYR1 RYR1 RANGRF RANGRF KCNK1 KCNK1 KCNK10 KCNK10 CAMK2D CAMK2D CAMK2B CAMK2B STIM1 STIM1 RYR3 RYR3 FAHD2A FAHD2A FKBP1B FKBP1B ATP2A3 ATP2A3 CASQ1 CASQ1 TBX5 TBX5 SCN2A SCN2A SCN10A SCN10A SCN3A SCN3A CLIC2 CLIC2 FGF12 FGF12 CACNG5 CACNG5 ORAI3 ORAI3 NPPB NPPB LOC105522975 LOC105522975 CACNA2D1 CACNA2D1 SLC8A3 SLC8A3 TRDN TRDN KCNK6 KCNK6 ITPR3 ITPR3 KCND3 KCND3 CACNB2 CACNB2 LOC105522976 LOC105522976 CACNG6 CACNG6 FGF13 FGF13 CASQ2 CASQ2 ATP2B2 ATP2B2 MAST4 MAST4 KCNK16 KCNK16 FAHD2B FAHD2B KCNIP1 KCNIP1 SRI SRI KCNK18 KCNK18 KCNK17 KCNK17 SLC8A2 SLC8A2 ORAI2 ORAI2 KCNK9 KCNK9 CAMK2A CAMK2A ATP1B1 ATP1B1 NPR2 NPR2 CACNG8 CACNG8 TRPC1 TRPC1 NPR1 NPR1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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KCNJ14Potassium voltage-gated channel subfamily J member 14. (436 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
ABCC9ATP binding cassette subfamily C member 9. (1512 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1129 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (294 aa)
HIPK2Homeodomain interacting protein kinase 2. (1197 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (228 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
ATP1A3Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1263 aa)
MAST1Microtubule associated serine/threonine kinase 1. (1679 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
NKX2-5NK2 homeobox 5. (324 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1028 aa)
ASPHD2Aspartate beta-hydroxylase domain containing 2. (369 aa)
FXYD6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (95 aa)
ECEL1Endothelin converting enzyme like 1. (692 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
NOS1Nitric oxide synthase 1. (1465 aa)
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (199 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (647 aa)
NPPANatriuretic peptide A. (153 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (428 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (254 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
ASPHAspartate beta-hydroxylase. (729 aa)
MMEMembrane metalloendopeptidase. (750 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1977 aa)
AKAP9A-kinase anchoring protein 9. (3909 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (238 aa)
KCNIP3Potassium voltage-gated channel interacting protein 3. (257 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1795 aa)
DMPKDM1 protein kinase. (632 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
GATA4GATA binding protein 4. (236 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (612 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
FXYD5FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (192 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (778 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
FXYD7FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (117 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (552 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
ENSCANP00000034207Uncharacterized protein. (89 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2015 aa)
NPPCNatriuretic peptide C. (126 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (220 aa)
KCNK7Potassium two pore domain channel subfamily K member 7; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (257 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2134 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (999 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2008 aa)
KCNK3Potassium channel subfamily K member. (353 aa)
KCNK13Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (361 aa)
MMEL1Uncharacterized protein. (350 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (250 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
STIM2Stromal interaction molecule 2. (755 aa)
CORINCorin, serine peptidase. (1042 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1743 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2697 aa)
FXYD3FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (144 aa)
MAST3Microtubule associated serine/threonine kinase 3. (1222 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (632 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1836 aa)
SLNUncharacterized protein. (31 aa)
KCNK5Potassium two pore domain channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (501 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
ENSCANP00000005529Uncharacterized protein. (134 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1081 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (445 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1027 aa)
KCNK4Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (357 aa)
RYR2Ryanodine receptor 2. (4920 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1680 aa)
LOC105522642Sodium/potassium-transporting ATPase subunit alpha. (641 aa)
ASPHD1Aspartate beta-hydroxylase domain containing 1. (389 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (103 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
ENSCANP00000002603Uncharacterized protein. (92 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (285 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (643 aa)
ENSCANP00000002281FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (89 aa)
SDR42E2Short chain dehydrogenase/reductase family 42E, member 2. (422 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ENSCANP00000001399Vomeronasal type-1 receptor. (291 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
RYR1Ryanodine receptor 1. (4758 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
KCNK1Potassium channel subfamily K member. (336 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (543 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
STIM1Stromal interaction molecule 1. (791 aa)
RYR3Ryanodine receptor 3. (4798 aa)
FAHD2AFumarylacetoacetate hydrolase domain containing 2A. (314 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1060 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
TBX5T-box transcription factor 5. (518 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2005 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1943 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2000 aa)
CLIC2Chloride intracellular channel 2. (247 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
ORAI3ORAI calcium release-activated calcium modulator 3. (295 aa)
NPPBNatriuretic peptide B. (134 aa)
LOC105522975Cation_ATPase_C domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (409 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1071 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
TRDNTriadin. (725 aa)
KCNK6Potassium channel subfamily K member. (312 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
LOC105522976Cation_ATPase_C domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (398 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (260 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (399 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1270 aa)
MAST4Microtubule associated serine/threonine kinase family member 4. (2441 aa)
KCNK16Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (309 aa)
FAHD2BFumarylacetoacetate hydrolase domain containing 2B. (314 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (241 aa)
SRIUncharacterized protein. (198 aa)
KCNK18Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (383 aa)
KCNK17Potassium channel subfamily K member. (332 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (848 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (262 aa)
KCNK9Potassium channel subfamily K member. (374 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
NPR2Guanylate cyclase. (1047 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (294 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
NPR1Guanylate cyclase. (958 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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