Your Input: | |
| | TAF3 | TATA-box binding protein associated factor 3. (879 aa) |
| | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa) |
| | EXO1 | Exonuclease 1. (846 aa) |
| | TXNDC11 | Thioredoxin domain containing 11. (900 aa) |
| | HIPK4 | Homeodomain interacting protein kinase 4. (616 aa) |
| | SSRP1 | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (574 aa) |
| | KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2003 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa) |
| | BRPF3 | Bromodomain and PHD finger containing 3. (1205 aa) |
| | EP300 | E1A binding protein p300. (2409 aa) |
| | TAF4B | TATA-box binding protein associated factor 4b. (867 aa) |
| | BRD9 | Bromodomain containing 9. (579 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (620 aa) |
| | LOC105524802 | Bromo domain-containing protein. (585 aa) |
| | PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1092 aa) |
| | POU4F2 | POU domain protein. (407 aa) |
| | ENSCANP00000012652 | Uncharacterized protein. (239 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1042 aa) |
| | TAF9B | TATA-box binding protein associated factor 9b. (251 aa) |
| | LOC105516286 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (449 aa) |
| | LOC105523183 | Ubiquitin-like domain-containing protein. (77 aa) |
| | ING2 | Inhibitor of growth protein. (280 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1059 aa) |
| | TAF5 | TATA-box binding protein associated factor 5. (800 aa) |
| | MBD3 | Methyl-CpG binding domain protein 3. (259 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (301 aa) |
| | LOC105501639 | WD_REPEATS_REGION domain-containing protein. (398 aa) |
| | AIRE | Autoimmune regulator. (509 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1197 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (966 aa) |
| | RFC5 | Replication factor C subunit 5. (343 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (636 aa) |
| | TP53BP2 | Tumor protein p53 binding protein 2. (1102 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (156 aa) |
| | LOC105510963 | Serine/threonine-protein phosphatase. (291 aa) |
| | MEAF6 | MYST/Esa1 associated factor 6. (171 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (708 aa) |
| | PLK5 | Polo like kinase 5. (336 aa) |
| | ENSCANP00000008095 | Uncharacterized protein. (83 aa) |
| | L3MBTL3 | L3MBTL histone methyl-lysine binding protein 3. (780 aa) |
| | ENSCANP00000007912 | Ubiquitin-like domain-containing protein. (121 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | PIP4P2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa) |
| | PML | Promyelocytic leukemia. (882 aa) |
| | RFC2 | Replication factor C subunit 2. (341 aa) |
| | ZNF385A | Zinc finger protein 385A. (414 aa) |
| | KMT5A | SET domain-containing protein. (326 aa) |
| | AURKA | Aurora kinase A; Belongs to the protein kinase superfamily. (403 aa) |
| | ING1 | Inhibitor of growth protein. (419 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | TAF9 | Uncharacterized protein. (264 aa) |
| | MAPKAPK5 | MAPK activated protein kinase 5. (481 aa) |
| | SETD9 | SET domain containing 9. (299 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
| | ZNF385C | Zinc finger protein 385C. (500 aa) |
| | ENSCANP00000004759 | Ubiquitin-like domain-containing protein. (147 aa) |
| | PRDM1 | PR/SET domain 1. (825 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (898 aa) |
| | RBBP4 | RB binding protein 4, chromatin remodeling factor. (425 aa) |
| | LOC105526098 | SET domain-containing protein. (333 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1102 aa) |
| | CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) |
| | RFFL | Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (355 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1210 aa) |
| | L3MBTL4 | L3MBTL histone methyl-lysine binding protein 4. (614 aa) |
| | LOC105527037 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (459 aa) |
| | ENSCANP00000002755 | WD_REPEATS_REGION domain-containing protein. (343 aa) |
| | LOC105517114 | Ubiquitin-like domain-containing protein. (156 aa) |
| | ING5 | Inhibitor of growth family member 5. (254 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (345 aa) |
| | CHEK2 | Checkpoint kinase 2. (589 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (306 aa) |
| | NUAK1 | NUAK family kinase 1. (657 aa) |
| | RBBP7 | RB binding protein 7, chromatin remodeling factor. (466 aa) |
| | RMI1 | RecQ mediated genome instability 1. (625 aa) |
| | RNF34 | Ring finger protein 34. (468 aa) |
| | ENSCANP00000000656 | Uncharacterized protein. (178 aa) |
| | LOC105521899 | Ubiquitin-like domain-containing protein. (146 aa) |
| | LOC105517842 | Uncharacterized protein. (253 aa) |
| | ENSCANP00000000485 | Ubiquitin-like domain-containing protein. (72 aa) |
| | ZNF385B | Zinc finger protein 385B. (471 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (544 aa) |
| | EHMT2 | Euchromatic histone lysine methyltransferase 2. (1266 aa) |
| | MDM2 | MDM2 proto-oncogene. (513 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (335 aa) |
| | ENSCANP00000022504 | Protein kinase domain-containing protein. (240 aa) |
| | RAD50 | Zinc-hook domain-containing protein. (1312 aa) |
| | ENSCANP00000022288 | Ubiquitin-like domain-containing protein. (79 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | AKT2 | AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa) |
| | SLC13A3-2 | Protein kinase domain-containing protein. (253 aa) |
| | TDRD3 | Tudor domain containing 3. (744 aa) |
| | NOC2L | NOC2 like nucleolar associated transcriptional repressor. (679 aa) |
| | LOC105510915 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa) |
| | RAD17 | RAD17 checkpoint clamp loader component. (639 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (323 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (635 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | ENSCANP00000020706 | Protein kinase domain-containing protein. (281 aa) |
| | TBPL1 | TATA-box binding protein like 1. (186 aa) |
| | DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (592 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (302 aa) |
| | RHNO1 | RAD9-HUS1-RAD1 interacting nuclear orphan 1. (240 aa) |
| | LOC105512501 | WD_REPEATS_REGION domain-containing protein. (396 aa) |
| | ENSCANP00000019642 | Ribosomal_S27 domain-containing protein. (93 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (755 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1926 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (418 aa) |
| | PHF20 | PHD finger protein 20. (1014 aa) |
| | GATAD2B | GATA zinc finger domain containing 2B. (593 aa) |
| | BRPF1 | Bromodomain and PHD finger containing 1. (1220 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1698 aa) |
| | C17orf113 | Chromosome 17 open reading frame 113. (436 aa) |
| | TAF2 | TATA-box binding protein associated factor 2. (1199 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1775 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (1989 aa) |
| | MDM4 | MDM4 regulator of p53. (340 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1247 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1001 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | ENSCANP00000016853 | P66_CC domain-containing protein. (184 aa) |
| | LOC105503496 | Ubiquitin-like domain-containing protein. (147 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (362 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | BLM | BLM RecQ like helicase. (1146 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (406 aa) |
| | ENSCANP00000024123 | Uncharacterized protein. (86 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (568 aa) |
| | GATAD2A | GATA-type domain-containing protein. (648 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | CHD4 | Uncharacterized protein. (1882 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (738 aa) |
| | SMYD2 | SET and MYND domain containing 2. (431 aa) |
| | CSNK2B | Uncharacterized protein. (296 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (621 aa) |
| | ENSCANP00000026204 | Metallophos domain-containing protein. (233 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (358 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (545 aa) |
| | BARD1 | BRCA1 associated RING domain 1. (718 aa) |
| | TTC5 | Tetratricopeptide repeat domain 5. (359 aa) |
| | WRN | WRN RecQ like helicase. (1431 aa) |
| | EHMT1 | Euchromatic histone lysine methyltransferase 1. (1291 aa) |
| | BRD1 | Bromodomain containing 1. (1058 aa) |
| | SGK1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (500 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (275 aa) |
| | FOXP4 | Forkhead box P4. (680 aa) |
| | PPP1R13L | Protein phosphatase 1 regulatory subunit 13 like. (782 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | DAXX | Death domain associated protein. (751 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (2000 aa) |
| | ENSCANP00000028719 | Protein kinase domain-containing protein. (328 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa) |
| | PIP4K2C | Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (340 aa) |
| | RFC4 | Replication factor C subunit 4. (363 aa) |
| | DYRK4 | Dual specificity tyrosine phosphorylation regulated kinase 4. (520 aa) |
| | AURKC | Aurora kinase C. (259 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (240 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (275 aa) |
| | TAF11 | TATA-box binding protein associated factor 11. (211 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (594 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | NUAK2 | NUAK family kinase 2. (671 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (476 aa) |
| | TAF12 | TATA-box binding protein associated factor 12. (213 aa) |
| | MEIOB | Meiosis specific with OB-fold. (392 aa) |
| | ENSCANP00000030363 | Uncharacterized protein. (396 aa) |
| | BANP | BTG3 associated nuclear protein. (525 aa) |
| | ENSCANP00000031588 | TAFII28 domain-containing protein. (210 aa) |
| | ENSCANP00000032089 | Uncharacterized protein. (120 aa) |
| | ENSCANP00000032612 | SWIB domain-containing protein. (72 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (390 aa) |
| | TAF7L | TATA-box binding protein associated factor 7 like. (460 aa) |
| | ENSCANP00000033351 | Uncharacterized protein. (84 aa) |
| | L3MBTL1 | Uncharacterized protein. (839 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | HIPK3 | Homeodomain interacting protein kinase 3. (1215 aa) |
| | RAD1 | RAD1 checkpoint DNA exonuclease. (280 aa) |
| | TPX2 | TPX2 microtubule nucleation factor. (732 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (667 aa) |
| | ENSCANP00000036167 | Uncharacterized protein. (105 aa) |
| | POU4F1 | POU domain protein. (288 aa) |
| | TOPBP1 | DNA topoisomerase II binding protein 1. (1527 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (344 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (654 aa) |
| | ENSCANP00000037307 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (493 aa) |
| | TBP | TATA-box binding protein. (328 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (179 aa) |
| | ENSCANP00000037911 | Uncharacterized protein. (361 aa) |
| | CCNG1 | Cyclin G1; Belongs to the cyclin family. (295 aa) |
| | BRD7 | Bromodomain containing 7. (642 aa) |
| | MAPKAP1 | MAPK associated protein 1. (522 aa) |
| | CDK1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa) |
| | POU4F3 | POU domain protein. (338 aa) |
| | RECQL4 | RecQ like helicase 4. (1154 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | ATRIP | ATR interacting protein. (791 aa) |
| | MTA2 | Metastasis associated 1 family member 2. (673 aa) |
| | USP2 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (576 aa) |
