STRINGSTRING
PLCG1 PLCG1 RPS27A RPS27A ENSCANP00000000485 ENSCANP00000000485 LOC105521899 LOC105521899 PTBP3 PTBP3 HNRNPF HNRNPF ENSCANP00000001411 ENSCANP00000001411 ERAS ERAS LOC105517114 LOC105517114 FGF1 FGF1 ENSCANP00000002557 ENSCANP00000002557 POLR2A POLR2A FNDC3A FNDC3A MKNK1 MKNK1 ENSCANP00000004759 ENSCANP00000004759 TIAL1 TIAL1 HRAS HRAS KRAS KRAS FGF23 FGF23 GTF2F2 GTF2F2 POLR2H POLR2H POLR2E POLR2E ENSCANP00000007912 ENSCANP00000007912 FGFBP3 FGFBP3 FGF10 FGF10 FGF22 FGF22 FRS3 FRS3 FGF8 FGF8 LOC105510963 LOC105510963 ENSCANP00000009565 ENSCANP00000009565 FGF20 FGF20 ENSCANP00000010829 ENSCANP00000010829 ENSCANP00000011220 ENSCANP00000011220 FGF5 FGF5 UBA52 UBA52 FGF6 FGF6 FGF17 FGF17 LOC105523183 LOC105523183 GTF2F1 GTF2F1 ESRP1 ESRP1 LOC105504658 LOC105504658 MAPK3 MAPK3 FGF16 FGF16 TIA1 TIA1 LOC105503496 LOC105503496 PIK3CA PIK3CA POLR2I POLR2I FGF9 FGF9 FGFR2 FGFR2 ENSCANP00000019642 ENSCANP00000019642 ENSCANP00000019829 ENSCANP00000019829 PIK3R1 PIK3R1 ENSCANP00000022288 ENSCANP00000022288 POLR2C POLR2C CSDE1 CSDE1 SHC1 SHC1 RBFOX2 RBFOX2 ENSCANP00000025012 ENSCANP00000025012 ENSCANP00000025796 ENSCANP00000025796 MAPK1 MAPK1 NCBP1 NCBP1 PPP2CB PPP2CB SPRY2 SPRY2 PPP2CA PPP2CA PPP2R1A PPP2R1A FGF7 FGF7 PTBP1 PTBP1 LOC105524249 LOC105524249 NCBP2 NCBP2 SOS1 SOS1 PTPN11 PTPN11 ENSCANP00000033979 ENSCANP00000033979 FGF2 FGF2 LOC105508369 LOC105508369 ENSCANP00000034934 ENSCANP00000034934 LOC105517265 LOC105517265 FNDC3B FNDC3B ENSCANP00000035946 ENSCANP00000035946 POLR2K POLR2K BRAF BRAF ENSCANP00000036145 ENSCANP00000036145 ESRP2 ESRP2 POLR2B POLR2B POLR2F POLR2F GAB1 GAB1 HNRNPA1 HNRNPA1 FGF3 FGF3 PTBP2 PTBP2 ENSCANP00000037455 ENSCANP00000037455 MKNK2 MKNK2 FGF18 FGF18 CBL CBL POLR2L POLR2L FRS2 FRS2 POLR2G POLR2G HNRNPM HNRNPM POLR2D POLR2D SRC SRC GRB2 GRB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
PTBP3Polypyrimidine tract binding protein 3. (568 aa)
HNRNPFUncharacterized protein. (415 aa)
ENSCANP00000001411Uncharacterized protein. (196 aa)
ERASES cell expressed Ras. (233 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
ENSCANP00000002557Uncharacterized protein. (535 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1986 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (464 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
TIAL1TIA1 cytotoxic granule associated RNA binding protein like 1. (392 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
POLR2HRNA polymerase II subunit H. (175 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
FGFBP3Fibroblast growth factor binding protein 3. (174 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (131 aa)
FRS3Fibroblast growth factor receptor substrate 3. (492 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
LOC105510963Serine/threonine-protein phosphatase. (291 aa)
ENSCANP00000009565Uncharacterized protein. (651 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
ENSCANP00000010829Uncharacterized protein. (272 aa)
ENSCANP00000011220Uncharacterized protein. (277 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (454 aa)
ESRP1Epithelial splicing regulatory protein 1. (681 aa)
LOC105504658Uncharacterized protein. (571 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
TIA1TIA1 cytotoxic granule associated RNA binding protein. (386 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGFR2Fibroblast growth factor receptor. (838 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
ENSCANP00000019829Uncharacterized protein. (98 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
CSDE1Uncharacterized protein. (844 aa)
SHC1SHC adaptor protein 1. (584 aa)
RBFOX2RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events. (389 aa)
ENSCANP00000025012RRM domain-containing protein. (248 aa)
ENSCANP00000025796Uncharacterized protein. (269 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
PPP2CASerine/threonine-protein phosphatase. (275 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (594 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PTBP1Polypyrimidine tract binding protein 1. (587 aa)
LOC105524249Uncharacterized protein. (308 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (138 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1310 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
ENSCANP00000033979Uncharacterized protein. (185 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC105508369Uncharacterized protein. (258 aa)
ENSCANP00000034934SH2 domain-containing protein. (183 aa)
LOC105517265RRM domain-containing protein. (457 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
ENSCANP00000035946Uncharacterized protein. (484 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (747 aa)
ENSCANP00000036145Uncharacterized protein. (268 aa)
ESRP2Epithelial splicing regulatory protein 2. (720 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
HNRNPA1Uncharacterized protein. (372 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (637 aa)
PTBP2Polypyrimidine tract binding protein 2. (537 aa)
ENSCANP00000037455Uncharacterized protein. (303 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (416 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
CBLCbl proto-oncogene. (888 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
FRS2Fibroblast growth factor receptor substrate 2. (521 aa)
POLR2GRNA polymerase II subunit G. (231 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (683 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
SRCTyrosine-protein kinase. (458 aa)
GRB2Uncharacterized protein. (156 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
Server load: low (40%) [HD]