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FGF23 FGF23 RPS27A RPS27A ENSCANP00000000485 ENSCANP00000000485 LOC105521899 LOC105521899 ERAS ERAS LOC105517114 LOC105517114 FGF1 FGF1 ENSCANP00000002557 ENSCANP00000002557 FNDC3A FNDC3A MKNK1 MKNK1 ENSCANP00000004759 ENSCANP00000004759 HRAS HRAS KRAS KRAS ENSCANP00000007912 ENSCANP00000007912 FRS3 FRS3 FGF8 FGF8 LOC105510963 LOC105510963 ENSCANP00000009565 ENSCANP00000009565 FGF20 FGF20 ENSCANP00000011220 ENSCANP00000011220 UBA52 UBA52 FGF6 FGF6 FGF17 FGF17 LOC105523183 LOC105523183 PLCG1 PLCG1 LOC105504658 LOC105504658 MAPK3 MAPK3 FGF16 FGF16 LOC105503496 LOC105503496 PIK3CA PIK3CA FGF9 FGF9 ENSCANP00000019642 ENSCANP00000019642 ENSCANP00000019829 ENSCANP00000019829 FGF19 FGF19 PIK3R1 PIK3R1 KLB KLB FGFR4 FGFR4 ENSCANP00000022288 ENSCANP00000022288 CSDE1 CSDE1 SHC1 SHC1 ENSCANP00000025796 ENSCANP00000025796 MAPK1 MAPK1 PPP2CB PPP2CB SPRY2 SPRY2 PPP2CA PPP2CA PPP2R1A PPP2R1A SOS1 SOS1 PTPN11 PTPN11 FGF2 FGF2 ENSCANP00000034934 ENSCANP00000034934 FNDC3B FNDC3B BRAF BRAF ENSCANP00000036145 ENSCANP00000036145 GAB1 GAB1 MKNK2 MKNK2 FGF18 FGF18 CBL CBL FRS2 FRS2 SRC SRC GRB2 GRB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
ERASES cell expressed Ras. (233 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
ENSCANP00000002557Uncharacterized protein. (535 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (464 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
FRS3Fibroblast growth factor receptor substrate 3. (492 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
LOC105510963Serine/threonine-protein phosphatase. (291 aa)
ENSCANP00000009565Uncharacterized protein. (651 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
ENSCANP00000011220Uncharacterized protein. (277 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
LOC105504658Uncharacterized protein. (571 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
ENSCANP00000019829Uncharacterized protein. (98 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (173 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
KLBKlotho beta. (1044 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
CSDE1Uncharacterized protein. (844 aa)
SHC1SHC adaptor protein 1. (584 aa)
ENSCANP00000025796Uncharacterized protein. (269 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
PPP2CASerine/threonine-protein phosphatase. (275 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (594 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1310 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
ENSCANP00000034934SH2 domain-containing protein. (183 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (747 aa)
ENSCANP00000036145Uncharacterized protein. (268 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (416 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
CBLCbl proto-oncogene. (888 aa)
FRS2Fibroblast growth factor receptor substrate 2. (521 aa)
SRCTyrosine-protein kinase. (458 aa)
GRB2Uncharacterized protein. (156 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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