STRINGSTRING
FN1 FN1 LRIG1 LRIG1 ENSCANP00000034934 ENSCANP00000034934 RAB4B RAB4B RAP1B RAP1B HGS HGS COL11A1 COL11A1 ENSCANP00000033724 ENSCANP00000033724 ENSCANP00000033455 ENSCANP00000033455 HGF HGF PTPN11 PTPN11 HPN HPN SOS1 SOS1 TNS4 TNS4 HGFAC HGFAC COL27A1 COL27A1 CRKL CRKL LAMB1 LAMB1 LAMC2 LAMC2 COL2A1 COL2A1 RANBP9 RANBP9 SH3GL1 SH3GL1 ENSCANP00000025796 ENSCANP00000025796 COL5A3 COL5A3 RAP1A RAP1A ITGA3 ITGA3 SH3GL2 SH3GL2 SHC1 SHC1 ENSCANP00000023725 ENSCANP00000023725 SPINT2 SPINT2 CSDE1 CSDE1 GGA3 GGA3 COL24A1 COL24A1 MET MET COL1A1 COL1A1 STAT3 STAT3 ENSCANP00000022288 ENSCANP00000022288 LAMA4 LAMA4 LOC105524044 LOC105524044 PIK3R1 PIK3R1 LAMA2 LAMA2 ENSCANP00000021474 ENSCANP00000021474 COL3A1 COL3A1 LAMC3 LAMC3 MEGF11 MEGF11 ENSCANP00000019829 ENSCANP00000019829 ENSCANP00000019642 ENSCANP00000019642 USP8 USP8 STAM STAM SPINT1 SPINT1 DOCK7 DOCK7 CRK CRK LAMB3 LAMB3 PIK3CA PIK3CA LOC105503496 LOC105503496 COL5A2 COL5A2 LOC105504658 LOC105504658 COL5A1 COL5A1 RANBP10 RANBP10 ENSCANP00000014775 ENSCANP00000014775 STAM2 STAM2 ITGB1 ITGB1 LAMA3 LAMA3 SH3GL3 SH3GL3 LOC105523183 LOC105523183 LAMA5 LAMA5 TNS1 TNS1 RAB4A RAB4A PTPN2 PTPN2 COL11A2 COL11A2 UBA52 UBA52 ENSCANP00000011220 ENSCANP00000011220 COL1A2 COL1A2 LAMA1 LAMA1 FNDC3B FNDC3B MUC20 MUC20 RAPGEF1 RAPGEF1 ENSCANP00000008262 ENSCANP00000008262 ENSCANP00000007912 ENSCANP00000007912 PTPN1 PTPN1 KRAS KRAS SH3KBP1 SH3KBP1 HRAS HRAS ENSCANP00000004759 ENSCANP00000004759 LAMB2 LAMB2 FNDC3A FNDC3A PTPRJ PTPRJ ENSCANP00000002557 ENSCANP00000002557 LOC105517114 LOC105517114 ENSCANP00000001668 ENSCANP00000001668 ERAS ERAS LOC105521899 LOC105521899 ARF6 ARF6 ENSCANP00000000485 ENSCANP00000000485 RPS27A RPS27A GRB2 GRB2 SRC SRC TNS3 TNS3 CBL CBL ITGA2 ITGA2 PTK2 PTK2 GAB1 GAB1 EPS15 EPS15 ENSCANP00000036145 ENSCANP00000036145
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FN1Fibronectin 1. (2450 aa)
LRIG1Uncharacterized protein. (1039 aa)
ENSCANP00000034934SH2 domain-containing protein. (183 aa)
RAB4BUncharacterized protein. (216 aa)
RAP1BUncharacterized protein. (184 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
COL11A1Collagen type XI alpha 1 chain. (1764 aa)
ENSCANP00000033724Uncharacterized protein. (794 aa)
ENSCANP00000033455BAR domain-containing protein. (299 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
HPNHepsin; Belongs to the peptidase S1 family. (417 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1310 aa)
TNS4Tensin 4. (715 aa)
HGFACHGF activator. (658 aa)
COL27A1Collagen type XXVII alpha 1 chain. (1839 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
LAMB1Laminin subunit beta 1. (1796 aa)
LAMC2Laminin subunit gamma 2. (1193 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
RANBP9RAN binding protein 9. (608 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (365 aa)
ENSCANP00000025796Uncharacterized protein. (269 aa)
COL5A3Collagen type V alpha 3 chain. (1716 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (337 aa)
SHC1SHC adaptor protein 1. (584 aa)
ENSCANP00000023725Uncharacterized protein. (175 aa)
SPINT2Serine peptidase inhibitor, Kunitz type 2. (249 aa)
CSDE1Uncharacterized protein. (844 aa)
GGA3Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (723 aa)
COL24A1Collagen type XXIV alpha 1 chain. (1705 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1404 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
STAT3Signal transducer and activator of transcription. (795 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
LAMA4Laminin subunit alpha 4. (1816 aa)
LOC105524044Uncharacterized protein. (999 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
LAMA2Laminin subunit alpha 2. (3066 aa)
ENSCANP00000021474Uncharacterized protein. (136 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
LAMC3Laminin subunit gamma 3. (1410 aa)
MEGF11Multiple EGF like domains 11. (1140 aa)
ENSCANP00000019829Uncharacterized protein. (98 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1118 aa)
STAMSignal transducing adaptor molecule. (540 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (531 aa)
DOCK7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2126 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
COL5A2Collagen type V alpha 2 chain. (1499 aa)
LOC105504658Uncharacterized protein. (571 aa)
COL5A1Collagen type V alpha 1 chain. (1768 aa)
RANBP10RAN binding protein 10. (656 aa)
ENSCANP00000014775Uncharacterized protein. (130 aa)
STAM2Signal transducing adaptor molecule 2. (525 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
LAMA3Laminin subunit alpha 3. (3235 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (354 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
LAMA5Laminin subunit alpha 5. (3457 aa)
TNS1Tensin 1. (1735 aa)
RAB4ARAB4A, member RAS oncogene family. (220 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (403 aa)
COL11A2Collagen type XI alpha 2 chain. (1613 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ENSCANP00000011220Uncharacterized protein. (277 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
LAMA1Laminin subunit alpha 1. (3054 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
MUC20Mucin 20, cell surface associated. (503 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1095 aa)
ENSCANP00000008262USP8_dimer domain-containing protein. (105 aa)
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (465 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (663 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1295 aa)
ENSCANP00000002557Uncharacterized protein. (535 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
ENSCANP00000001668Uncharacterized protein. (329 aa)
ERASES cell expressed Ras. (233 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
GRB2Uncharacterized protein. (156 aa)
SRCTyrosine-protein kinase. (458 aa)
TNS3Tensin 3. (1445 aa)
CBLCbl proto-oncogene. (888 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (886 aa)
ENSCANP00000036145Uncharacterized protein. (268 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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