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| | DNA2 | DNA replication helicase/nuclease 2. (1042 aa) |
| | CENPK | Centromere protein K. (269 aa) |
| | TRUB1 | TruB pseudouridine synthase family member 1. (350 aa) |
| | STN1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (368 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (301 aa) |
| | PIF1 | ATP-dependent DNA helicase; Belongs to the helicase family. (587 aa) |
| | LOC105501639 | WD_REPEATS_REGION domain-containing protein. (398 aa) |
| | CHTF18 | Uncharacterized protein. (814 aa) |
| | RFC5 | Replication factor C subunit 5. (343 aa) |
| | DKC1 | Dyskerin pseudouridine synthase 1. (514 aa) |
| | RFC1 | Replication factor C subunit 1. (1148 aa) |
| | POLR2E | RNA polymerase II subunit E. (210 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (466 aa) |
| | RFC2 | Replication factor C subunit 2. (341 aa) |
| | RCBTB1 | RCC1 and BTB domain containing protein 1. (531 aa) |
| | POLR2H | RNA polymerase II subunit H. (175 aa) |
| | TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (437 aa) |
| | CTC1 | CST telomere replication complex component 1. (1212 aa) |
| | ENSCANP00000006424 | annotation not available (103 aa) |
| | ITGB3BP | Integrin subunit beta 3 binding protein. (215 aa) |
| | LOC105526757 | Histone H4. (103 aa) |
| | LOC105526753 | Histone H2A type 1. (130 aa) |
| | LOC105526752 | Histone H4. (103 aa) |
| | RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1335 aa) |
| | LOC105509448 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (245 aa) |
| | LOC105513908 | Histone H2B type 1-J. (126 aa) |
| | H2BC14 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | NPM1 | Nucleophosmin 1. (293 aa) |
| | LOC105506722 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | LOC105513905 | Histone H4. (103 aa) |
| | LOC105513883 | Histone H4. (103 aa) |
| | H2AZ2 | Histone H2A; Belongs to the histone H2A family. (102 aa) |
| | RBBP4 | RB binding protein 4, chromatin remodeling factor. (425 aa) |
| | LOC105513873 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC105506127 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | LOC105519951 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC105526748 | Histone H4. (103 aa) |
| | LOC105526741-4 | Histone H2B type 1. (126 aa) |
| | LOC105509399 | Histone H3; Belongs to the histone H3 family. (135 aa) |
| | H2BC3 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | H2BC1 | Histone H2B; Belongs to the histone H2B family. (127 aa) |
| | LOC105526740 | Histone H4. (103 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | LOC105526737 | Histone H4. (103 aa) |
| | POLR2A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1986 aa) |
| | LOC105526741-3 | Histone H2B type 1. (126 aa) |
| | LOC105513882 | Histone H4. (103 aa) |
| | LOC105513874 | Histone H4. (103 aa) |
| | POT1 | Protection of telomeres 1. (634 aa) |
| | LOC105526734 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | ENSCANP00000002791 | Histone H2B; Belongs to the histone H2B family. (129 aa) |
| | ENSCANP00000002755 | WD_REPEATS_REGION domain-containing protein. (343 aa) |
| | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1070 aa) |
| | LOC105507268 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | H2AX | Histone H2A; Belongs to the histone H2A family. (143 aa) |
| | LOC105510607 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | ENSCANP00000002473 | Histone H2B; Belongs to the histone H2B family. (134 aa) |
| | LOC105526736 | Histone H4. (103 aa) |
| | LOC105526758 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | H2AJ | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | H2BC5 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | CENPT | Centromere protein T. (560 aa) |
| | ENSCANP00000001382 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | RCBTB2 | RCC1 and BTB domain containing protein 2. (561 aa) |
| | H2AC7 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | H2AC6 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | LOC105520452 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | LOC105526741-2 | Histone H2B type 1. (126 aa) |
| | ENSCANP00000000012 | Nucleoplasmin domain-containing protein. (237 aa) |
| | POLD2 | DNA polymerase delta 2, accessory subunit. (504 aa) |
| | CENPP | Uncharacterized protein. (115 aa) |
| | LOC105526741 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | ENSCANP00000000858 | Histone H2B; Belongs to the histone H2B family. (136 aa) |
| | H2BC15 | Histone H2B; Belongs to the histone H2B family. (166 aa) |
| | NOP10 | Uncharacterized protein. (64 aa) |
| | RBBP7 | RB binding protein 7, chromatin remodeling factor. (466 aa) |
| | POLD4 | Uncharacterized protein. (107 aa) |
| | CENPQ | Centromere protein Q. (268 aa) |
| | POLR2D | RNA polymerase II subunit D. (142 aa) |
| | ENSCANP00000039811 | Uncharacterized protein. (263 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) |
| | RECQL4 | RecQ like helicase 4. (1154 aa) |
| | ANKRD28 | Ankyrin repeat domain 28. (1086 aa) |
| | POLR2G | RNA polymerase II subunit G. (231 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | POLR2L | RNA polymerase II subunit L. (67 aa) |
| | ENSCANP00000038681 | Uncharacterized protein. (56 aa) |
| | ENSCANP00000037817 | Uncharacterized protein. (157 aa) |
| | POLR2F | RNA polymerase II subunit F. (158 aa) |
| | POLR2B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa) |
| | ENSCANP00000036099 | Mis18 domain-containing protein. (220 aa) |
| | LOC105521072 | Uncharacterized protein. (280 aa) |
| | POLR2K | RNA polymerase II subunit K. (58 aa) |
| | RSF1 | Remodeling and spacing factor 1. (1422 aa) |
| | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1052 aa) |
| | TINF2 | TINF2_N domain-containing protein. (451 aa) |
| | H2BW2 | H2B histone family member M; Belongs to the histone H2B family. (153 aa) |
| | ENSCANP00000034865 | Histone H2A; Belongs to the histone H2A family. (122 aa) |
| | LOC105517382 | Uncharacterized protein. (191 aa) |
| | CENPO | Centromere protein O. (298 aa) |
| | CENPI | Centromere protein I. (754 aa) |
| | CENPN | Centromere protein N. (339 aa) |
| | CENPH | Centromere protein H. (221 aa) |
| | ENSCANP00000033684 | Histone H2A; Belongs to the histone H2A family. (107 aa) |
| | H3F3A | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | PPP6C | Serine/threonine-protein phosphatase. (305 aa) |
| | HJURP | Holliday junction recognition protein. (721 aa) |
| | LOC105505861 | Histone H2A; Belongs to the histone H2A family. (116 aa) |
| | ENSCANP00000032089 | Uncharacterized protein. (120 aa) |
| | RBPMS2 | Uncharacterized protein. (94 aa) |
| | TEN1 | Uncharacterized protein. (123 aa) |
| | SHQ1 | SHQ1, H/ACA ribonucleoprotein assembly factor. (572 aa) |
| | GAR1 | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (217 aa) |
| | WRAP53 | WD repeat containing antisense to TP53. (518 aa) |
| | POLD3 | Uncharacterized protein. (454 aa) |
| | MEIOB | Meiosis specific with OB-fold. (392 aa) |
| | POLA1 | DNA polymerase. (1474 aa) |
| | H3F3B | Histone domain-containing protein. (191 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | H2AC20 | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | H2BC21 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC105524985 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | H2BU1 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC105524989 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | ENSCANP00000029611 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (151 aa) |
| | RFC4 | Replication factor C subunit 4. (363 aa) |
| | DAXX | Death domain associated protein. (751 aa) |
| | LOC105520302 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | OIP5 | Mis18 domain-containing protein. (229 aa) |
| | WRN | WRN RecQ like helicase. (1431 aa) |
| | CHTF8 | Chromosome transmission fidelity factor 8. (121 aa) |
| | LOC105517182 | Uncharacterized protein. (291 aa) |
| | CENPX | Centromere protein X. (133 aa) |
| | ENSCANP00000026071 | RFC1 domain-containing protein. (136 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (621 aa) |
| | TERF2IP | TERF2 interacting protein. (235 aa) |
| | CENPW | Centromere protein W. (103 aa) |
| | PPP6R2 | Protein phosphatase 6 regulatory subunit 2. (939 aa) |
| | MIS18BP1 | MIS18 binding protein 1. (1131 aa) |
| | TERF2 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (471 aa) |
| | CENPL | Centromere protein L. (390 aa) |
| | POLR2C | RNA polymerase II subunit C. (275 aa) |
| | BLM | BLM RecQ like helicase. (1146 aa) |
| | LOC105517192 | Uncharacterized protein. (280 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa) |
| | LOC105508421 | TINF2_N domain-containing protein. (454 aa) |
| | KNL1 | Kinetochore scaffold 1. (2204 aa) |
| | CENPA | Centromere protein A. (113 aa) |
| | ENSCANP00000020858 | Uncharacterized protein. (185 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1059 aa) |
| | LOC105512501 | WD_REPEATS_REGION domain-containing protein. (396 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | POLD1 | DNA polymerase delta 1, catalytic subunit. (1012 aa) |
| | LOC105519471 | Uncharacterized protein. (291 aa) |
| | PPP6R3 | Protein phosphatase 6 regulatory subunit 3. (879 aa) |
| | LOC105512667 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | ATRX | ATRX chromatin remodeler. (2490 aa) |
| | CENPU | Centromere protein U. (417 aa) |
| | CENPM | Centromere protein M. (180 aa) |
| | POLR2I | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa) |
| | ANKRD44 | Ankyrin repeat domain 44. (553 aa) |
| | ENSCANP00000016884 | Uncharacterized protein. (77 aa) |
| | ACD | ACD shelterin complex subunit and telomerase recruitment factor. (485 aa) |
| | NHP2 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (153 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (362 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (574 aa) |
| | ENSCANP00000014925 | Histone H2B; Belongs to the histone H2B family. (121 aa) |
| | LOC105501368 | Uncharacterized protein. (449 aa) |
| | LOC105515702 | AAA domain-containing protein. (798 aa) |
| | LIG1 | DNA ligase. (919 aa) |
| | CENPC | Centromere protein C. (945 aa) |
| | ANKRD66 | Ankyrin repeat domain 66. (250 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (509 aa) |
| | MIS18A | MIS18 kinetochore protein A. (232 aa) |
| | DSCC1 | DNA replication and sister chromatid cohesion 1. (393 aa) |
