STRINGSTRING
CCNQ CCNQ CDC73 CDC73 ERCC3 ERCC3 PRF1 PRF1 LOC105508545 LOC105508545 POLR2A POLR2A LOC105517016 LOC105517016 LOC105514185 LOC105514185 NELFE NELFE GTF2F2 GTF2F2 POLR2H POLR2H ENSCANP00000007584 ENSCANP00000007584 POLR2E POLR2E SUPT6H SUPT6H TCEANC TCEANC CCNT2 CCNT2 LEO1 LEO1 ENSCANP00000010034 ENSCANP00000010034 ELL ELL ELOC ELOC AFF4 AFF4 GTF2F1 GTF2F1 TCEA3 TCEA3 EAF2 EAF2 SSRP1 SSRP1 WDR61 WDR61 LOC105503213 LOC105503213 SUPT16H SUPT16H MLLT1 MLLT1 POLR2I POLR2I CDK9 CDK9 NELFB NELFB ENSCANP00000019618 ENSCANP00000019618 LOC105509844 LOC105509844 LOC105524160 LOC105524160 MNAT1 MNAT1 EAF1 EAF1 ENSCANP00000021879 ENSCANP00000021879 SUPT4H1 SUPT4H1 CDK7 CDK7 LOC105514296 LOC105514296 ENSCANP00000022785 ENSCANP00000022785 POLR2C POLR2C NELFCD NELFCD LOC105521838 LOC105521838 PAF1 PAF1 CTDP1 CTDP1 CCNH CCNH RTF1 RTF1 NCBP1 NCBP1 CCNK CCNK GTF2H5 GTF2H5 AFF1 AFF1 GTF2H1 GTF2H1 NELFA NELFA TCEA1 TCEA1 CTR9 CTR9 MLLT3 MLLT3 NCBP2 NCBP2 CINP CINP SLC39A13 SLC39A13 LOC105517070 LOC105517070 ERCC2 ERCC2 TCEA2 TCEA2 ENSCANP00000035075 ENSCANP00000035075 TCEANC2 TCEANC2 POLR2K POLR2K POLR2B POLR2B POLR2F POLR2F ENSCANP00000037504 ENSCANP00000037504 ENSCANP00000038075 ENSCANP00000038075 CCNT1 CCNT1 IWS1 IWS1 POLR2L POLR2L POLR2G POLR2G C6orf15 C6orf15 GTF2H4 GTF2H4 POLR2D POLR2D SUPT5H SUPT5H
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCNQCYCLIN domain-containing protein; Belongs to the cyclin family. (226 aa)
CDC73Cell division cycle 73. (531 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
PRF1Perforin 1. (555 aa)
LOC105508545Uncharacterized protein. (162 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1986 aa)
LOC105517016TFIIS N-terminal domain-containing protein. (714 aa)
LOC105514185Ubiquitin-like domain-containing protein. (118 aa)
NELFENegative elongation factor complex member E. (395 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
POLR2HRNA polymerase II subunit H. (175 aa)
ENSCANP00000007584Ubiquitin-like domain-containing protein. (120 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (380 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (716 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa)
ENSCANP00000010034Uncharacterized protein. (122 aa)
ELLElongation factor for RNA polymerase II. (621 aa)
ELOCSkp1_POZ domain-containing protein; Belongs to the SKP1 family. (113 aa)
AFF4AF4/FMR2 family member 4. (1163 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (454 aa)
TCEA3Transcription elongation factor A3. (348 aa)
EAF2ELL associated factor 2. (221 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa)
WDR61WD repeat domain 61. (305 aa)
LOC105503213Uncharacterized protein. (266 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
MLLT1MLLT1 super elongation complex subunit. (561 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
NELFBNegative elongation factor complex member B. (573 aa)
ENSCANP00000019618CYCLIN domain-containing protein; Belongs to the cyclin family. (295 aa)
LOC105509844Uncharacterized protein. (577 aa)
LOC105524160General transcription factor IIH subunit. (395 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
EAF1ELL associated factor 1. (268 aa)
ENSCANP00000021879Uncharacterized protein. (88 aa)
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
CDK7Cyclin dependent kinase 7. (309 aa)
LOC105514296Uncharacterized protein. (755 aa)
ENSCANP00000022785Protein kinase domain-containing protein. (322 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
NELFCDUncharacterized protein. (581 aa)
LOC105521838TFIIS N-terminal domain-containing protein. (786 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (531 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (859 aa)
CCNHCyclin H; Belongs to the cyclin family. (339 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (644 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
CCNKCyclin K; Belongs to the cyclin family. (515 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
AFF1AF4/FMR2 family member 1. (1223 aa)
GTF2H1General transcription factor IIH subunit 1. (557 aa)
NELFANegative elongation factor complex member A. (481 aa)
TCEA1Transcription elongation factor A1. (301 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
MLLT3MLLT3 super elongation complex subunit. (565 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (138 aa)
CINPCyclin dependent kinase 2 interacting protein. (227 aa)
SLC39A13Solute carrier family 39 member 13. (370 aa)
LOC105517070Uncharacterized protein. (488 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
TCEA2Transcription elongation factor A2. (272 aa)
ENSCANP00000035075Uncharacterized protein. (208 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain containing 2. (208 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
ENSCANP00000037504Uncharacterized protein. (122 aa)
ENSCANP00000038075Uncharacterized protein; Belongs to the SKP1 family. (107 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (819 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
POLR2GRNA polymerase II subunit G. (231 aa)
C6orf15Chromosome 6 open reading frame 15. (312 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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