32 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C6orf15	Chromosome 6 open reading frame 15. (312 aa)
	ERCC3	ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
	LOC105508545	Uncharacterized protein. (162 aa)
	POLR2A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1986 aa)
	GTF2F2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
	POLR2H	RNA polymerase II subunit H. (175 aa)
	POLR2E	RNA polymerase II subunit E. (210 aa)
	GTF2F1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (454 aa)
	LOC105503213	Uncharacterized protein. (266 aa)
	POLR2I	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (105 aa)
	LOC105524160	General transcription factor IIH subunit. (395 aa)
	MNAT1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
	RNMT	mRNA cap guanine-N7 methyltransferase. (503 aa)
	CDK7	Cyclin dependent kinase 7. (309 aa)
	ENSCANP00000022785	Protein kinase domain-containing protein. (322 aa)
	POLR2C	RNA polymerase II subunit C. (275 aa)
	CCNH	Cyclin H; Belongs to the cyclin family. (339 aa)
	GTF2H5	General transcription factor IIH subunit 5. (71 aa)
	RNGTT	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)
	GTF2H1	General transcription factor IIH subunit 1. (557 aa)
	LOC105517070	Uncharacterized protein. (488 aa)
	ERCC2	ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
	ENSCANP00000035075	Uncharacterized protein. (208 aa)
	POLR2K	RNA polymerase II subunit K. (58 aa)
	POLR2B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
	POLR2F	RNA polymerase II subunit F. (158 aa)
	POLR2L	RNA polymerase II subunit L. (67 aa)
	POLR2G	RNA polymerase II subunit G. (231 aa)
	GTF2H4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
	POLR2D	RNA polymerase II subunit D. (142 aa)
	SUPT5H	Transcription elongation factor SPT5. (1087 aa)
	DUSP11	Dual specificity phosphatase 11. (378 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C6orf15	CCNH	ENSCANP00000039517	ENSCANP00000025973	Chromosome 6 open reading frame 15.	Cyclin H; Belongs to the cyclin family.	0.780
C6orf15	CDK7	ENSCANP00000039517	ENSCANP00000022339	Chromosome 6 open reading frame 15.	Cyclin dependent kinase 7.	0.641
C6orf15	DUSP11	ENSCANP00000039517	ENSCANP00000040223	Chromosome 6 open reading frame 15.	Dual specificity phosphatase 11.	0.855
C6orf15	ENSCANP00000022785	ENSCANP00000039517	ENSCANP00000022785	Chromosome 6 open reading frame 15.	Protein kinase domain-containing protein.	0.641
C6orf15	ENSCANP00000035075	ENSCANP00000039517	ENSCANP00000035075	Chromosome 6 open reading frame 15.	Uncharacterized protein.	0.608
C6orf15	GTF2F1	ENSCANP00000039517	ENSCANP00000013868	Chromosome 6 open reading frame 15.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.709
C6orf15	GTF2F2	ENSCANP00000039517	ENSCANP00000007190	Chromosome 6 open reading frame 15.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.918
C6orf15	GTF2H1	ENSCANP00000039517	ENSCANP00000029543	Chromosome 6 open reading frame 15.	General transcription factor IIH subunit 1.	0.681
C6orf15	GTF2H4	ENSCANP00000039517	ENSCANP00000039764	Chromosome 6 open reading frame 15.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.742
C6orf15	LOC105503213	ENSCANP00000039517	ENSCANP00000015237	Chromosome 6 open reading frame 15.	Uncharacterized protein.	0.962
C6orf15	LOC105508545	ENSCANP00000039517	ENSCANP00000003245	Chromosome 6 open reading frame 15.	Uncharacterized protein.	0.608
C6orf15	LOC105517070	ENSCANP00000039517	ENSCANP00000033348	Chromosome 6 open reading frame 15.	Uncharacterized protein.	0.681
C6orf15	MNAT1	ENSCANP00000039517	ENSCANP00000020167	Chromosome 6 open reading frame 15.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.694
C6orf15	POLR2A	ENSCANP00000039517	ENSCANP00000003277	Chromosome 6 open reading frame 15.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.826
C6orf15	POLR2B	ENSCANP00000039517	ENSCANP00000036332	Chromosome 6 open reading frame 15.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.981
C6orf15	POLR2C	ENSCANP00000039517	ENSCANP00000022877	Chromosome 6 open reading frame 15.	RNA polymerase II subunit C.	0.978
C6orf15	POLR2D	ENSCANP00000039517	ENSCANP00000039979	Chromosome 6 open reading frame 15.	RNA polymerase II subunit D.	0.977
C6orf15	POLR2E	ENSCANP00000039517	ENSCANP00000007829	Chromosome 6 open reading frame 15.	RNA polymerase II subunit E.	0.978
C6orf15	POLR2F	ENSCANP00000039517	ENSCANP00000036386	Chromosome 6 open reading frame 15.	RNA polymerase II subunit F.	0.971
C6orf15	POLR2G	ENSCANP00000039517	ENSCANP00000039084	Chromosome 6 open reading frame 15.	RNA polymerase II subunit G.	0.977