STRINGSTRING
SH3KBP1 SH3KBP1 SH3GL3 SH3GL3 EPS15 EPS15 HGS HGS ENSCANP00000033455 ENSCANP00000033455 SH3GL1 SH3GL1 SH3GL2 SH3GL2 MET MET ENSCANP00000019642 ENSCANP00000019642 STAM STAM LOC105503496 LOC105503496 STAM2 STAM2 RPS27A RPS27A LOC105517114 LOC105517114 UBA52 UBA52 GRB2 GRB2 CBL CBL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SH3KBP1SH3 domain containing kinase binding protein 1. (663 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (354 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (886 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
ENSCANP00000033455BAR domain-containing protein. (299 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (365 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (337 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1404 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
STAMSignal transducing adaptor molecule. (540 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
STAM2Signal transducing adaptor molecule 2. (525 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
GRB2Uncharacterized protein. (156 aa)
CBLCbl proto-oncogene. (888 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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