STRINGSTRING
RPS27A RPS27A PSMB7 PSMB7 TCF7L2 TCF7L2 HDAC4 HDAC4 ENSCANP00000022288 ENSCANP00000022288 ENSCANP00000017387 ENSCANP00000017387 PSMD2 PSMD2 PSMC3 PSMC3 PSMC4 PSMC4 ENSCANP00000019642 ENSCANP00000019642 CCND1 CCND1 ENSCANP00000020516 ENSCANP00000020516 PSMD10 PSMD10 ZFHX4 ZFHX4 PSMA1 PSMA1 UBA52 UBA52 PSME2 PSME2 CTNNB1 CTNNB1 ENSCANP00000011827 ENSCANP00000011827 LOC105523183 LOC105523183 RBPJL RBPJL ENSCANP00000012853 ENSCANP00000012853 PSMA4 PSMA4 PSMA5 PSMA5 ENSCANP00000013611 ENSCANP00000013611 PSMD12 PSMD12 PSMB6 PSMB6 PSMC6 PSMC6 EP300 EP300 LOC105518935 LOC105518935 MAML1 MAML1 SNW1 SNW1 SPP1 SPP1 YAP1 YAP1 PSMA7 PSMA7 PSMB10 PSMB10 PSMB5 PSMB5 TEAD1 TEAD1 PSMD14 PSMD14 ENSCANP00000016154 ENSCANP00000016154 RUNX1 RUNX1 ZFHX2 ZFHX2 PSME1 PSME1 LOC105503496 LOC105503496 ENSCANP00000016508 ENSCANP00000016508 PSMD1 PSMD1 ENSCANP00000010884 ENSCANP00000010884 ZFHX3 ZFHX3 PSMC5 PSMC5 PSMD13 PSMD13 PSMD9 PSMD9 TEAD2 TEAD2 SRC SRC ITGAL ITGAL PSMD3 PSMD3 MAML3 MAML3 TCF7L1 TCF7L1 PSMC2 PSMC2 ENSCANP00000032549 ENSCANP00000032549 PSMD7 PSMD7 PSMA3 PSMA3 PSMD4 PSMD4 CREBBP CREBBP PSMB4 PSMB4 RUNX3 RUNX3 MYC MYC WWTR1 WWTR1 LOC105500584 LOC105500584 LOC105520745 LOC105520745 PSMA2 PSMA2 SMAD4 SMAD4 LOC105521476 LOC105521476 SMURF1 SMURF1 TP53 TP53 PSMB1 PSMB1 TCF7 TCF7 PSMF1 PSMF1 LOC105520594 LOC105520594 NOTCH1 NOTCH1 RORC RORC PSMB8 PSMB8 SMURF2 SMURF2 JAG1 JAG1 ENSCANP00000026188 ENSCANP00000026188 ENSCANP00000026021 ENSCANP00000026021 CDKN1A CDKN1A MAMLD1 MAMLD1 PSMD11 PSMD11 PSMD8 PSMD8 ENSCANP00000023943 ENSCANP00000023943 TEAD3 TEAD3 CCN2 CCN2 HES1 HES1 KAT2B KAT2B BRD2 BRD2 ENSCANP00000036083 ENSCANP00000036083 FNDC3B FNDC3B PSMB9 PSMB9 RBPJ RBPJ ERAS ERAS SMAD3 SMAD3 LOC105521899 LOC105521899 ENSCANP00000000485 ENSCANP00000000485 LEF1 LEF1 ENSCANP00000000468 ENSCANP00000000468 PSME3 PSME3 TEAD4 TEAD4 ENSCANP00000010775 ENSCANP00000010775 KAT2A KAT2A ENSCANP00000010057 ENSCANP00000010057 MAML2 MAML2 PSMD5 PSMD5 BCL2L11 BCL2L11 ENSCANP00000008806 ENSCANP00000008806 TGFB1 TGFB1 PSMB2 PSMB2 ENSCANP00000007912 ENSCANP00000007912 PSMA6 PSMA6 ENSCANP00000007099 ENSCANP00000007099 FOXO3 FOXO3 NINJ2 NINJ2 KRAS KRAS LOC105508356 LOC105508356 ENSCANP00000006295 ENSCANP00000006295 PSMD6 PSMD6 ENSCANP00000004759 ENSCANP00000004759 FNDC3A FNDC3A LOC105516879 LOC105516879 ITGA4 ITGA4 LOC105517114 LOC105517114
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSMB7Proteasome subunit beta. (277 aa)
TCF7L2Transcription factor 7 like 2. (577 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1090 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
ENSCANP00000017387Proteasome subunit beta. (181 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (747 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
ENSCANP00000020516CSN8_PSD8_EIF3K domain-containing protein. (254 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ZFHX4Zinc finger homeobox 4. (3615 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PSME2Proteasome activator subunit 2. (255 aa)
CTNNB1Catenin beta 1. (781 aa)
ENSCANP00000011827Uncharacterized protein. (106 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
RBPJLRecombination signal binding protein for immunoglobulin kappa J region like. (522 aa)
ENSCANP00000012853C2 domain-containing protein. (51 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
ENSCANP00000013611AAA domain-containing protein. (371 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMB6Proteasome subunit beta. (245 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
EP300E1A binding protein p300. (2409 aa)
LOC105518935AAA domain-containing protein; Belongs to the AAA ATPase family. (426 aa)
MAML1Mastermind like transcriptional coactivator 1. (924 aa)
SNW1SNW domain containing 1. (571 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
YAP1Yes associated protein 1. (479 aa)
PSMA7Proteasome endopeptidase complex. (178 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB5Proteasome subunit beta. (263 aa)
TEAD1TEA domain transcription factor 1. (434 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
ENSCANP00000016154Uncharacterized protein. (82 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (455 aa)
ZFHX2Zinc finger homeobox 2. (2571 aa)
PSME1Proteasome activator subunit 1. (247 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
ENSCANP00000016508JAB_MPN domain-containing protein. (167 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
ENSCANP00000010884Uncharacterized protein. (338 aa)
ZFHX3Zinc finger homeobox 3. (3690 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (399 aa)
PSMD9PDZ domain-containing protein. (223 aa)
TEAD2TEA domain transcription factor 2. (377 aa)
SRCTyrosine-protein kinase. (458 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1103 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
MAML3Mastermind like transcriptional coactivator 3. (1126 aa)
TCF7L1Transcription factor 7 like 1. (512 aa)
PSMC2AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
ENSCANP00000032549AAA_lid_3 domain-containing protein. (354 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (380 aa)
CREBBPCREB binding protein. (2117 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (366 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
LOC105500584Uncharacterized protein. (180 aa)
LOC105520745AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
LOC10552147626S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (834 aa)
SMURF1E3 ubiquitin-protein ligase. (763 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa)
PSMB1Proteasome subunit beta. (241 aa)
TCF7Transcription factor 7. (398 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
LOC105520594AAA domain-containing protein; Belongs to the AAA ATPase family. (442 aa)
NOTCH1Notch receptor 1. (2559 aa)
RORCRAR related orphan receptor C. (560 aa)
PSMB8Proteasome subunit beta. (284 aa)
SMURF2E3 ubiquitin-protein ligase. (734 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1089 aa)
ENSCANP00000026188AAA domain-containing protein; Belongs to the AAA ATPase family. (430 aa)
ENSCANP00000026021NET domain-containing protein. (331 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
MAMLD1Mastermind like domain containing 1. (990 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (410 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
ENSCANP00000023943Proteasome subunit beta. (204 aa)
TEAD3Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (435 aa)
CCN2Cellular communication network factor 2. (301 aa)
HES1Hes family bHLH transcription factor 1. (253 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (778 aa)
BRD2Uncharacterized protein. (823 aa)
ENSCANP00000036083Uncharacterized protein. (111 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
PSMB9Proteasome subunit beta 9. (177 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (524 aa)
ERASES cell expressed Ras. (233 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
ENSCANP00000000468ATPase_AAA_core domain-containing protein. (421 aa)
PSME3Proteasome activator subunit 3. (170 aa)
TEAD4Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (434 aa)
ENSCANP00000010775ATPase_AAA_core domain-containing protein. (385 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
ENSCANP00000010057AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
MAML2Mastermind like transcriptional coactivator 2. (1156 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
ENSCANP00000008806Uncharacterized protein. (357 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
PSMB2Proteasome subunit beta. (201 aa)
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
ENSCANP00000007099Uncharacterized protein. (213 aa)
FOXO3Forkhead box O3. (544 aa)
NINJ2Ninjurin 2. (189 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
LOC105508356PCI domain-containing protein. (411 aa)
ENSCANP00000006295ANK_REP_REGION domain-containing protein. (151 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
LOC105516879Proteasome endopeptidase complex. (214 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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