STRINGSTRING
LPL LPL APOC2 APOC2 ANGPTL8 ANGPTL8 ANGPTL3 ANGPTL3 PCSK4 PCSK4 LMF1 LMF1 FGF21 FGF21 APOA4 APOA4 FURIN FURIN APOA5 APOA5 LMF2 LMF2 GPIHBP1 GPIHBP1 LOC105524083 LOC105524083 LIPC LIPC PCSK6 PCSK6 MBTPS1 MBTPS1 MBTPS2 MBTPS2 CIDEC CIDEC PCSK5 PCSK5 CREB3L3 CREB3L3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
APOC2Apolipoprotein C2. (101 aa)
ANGPTL8Angiopoietin like 8. (198 aa)
ANGPTL3Angiopoietin like 3. (460 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (707 aa)
LMF1Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (567 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
APOA4Apolipoprotein A4. (412 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
APOA5Apolipoprotein A5. (366 aa)
LMF2Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (707 aa)
GPIHBP1Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. (141 aa)
LOC105524083CIDE-N domain-containing protein. (126 aa)
LIPCLipase C, hepatic type. (499 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (928 aa)
MBTPS1Membrane bound transcription factor peptidase, site 1. (1052 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (520 aa)
CIDECCIDE-N domain-containing protein. (133 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1758 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (415 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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