STRINGSTRING
LOC105517114 LOC105517114 PSENEN PSENEN MIB1 MIB1 ADAM10 ADAM10 TACC3 TACC3 NCSTN NCSTN PSEN2 PSEN2 NEURL1B NEURL1B DLL1 DLL1 JAG1 JAG1 PSEN1 PSEN1 YBX1 YBX1 APH1A APH1A ENSCANP00000022288 ENSCANP00000022288 ENSCANP00000019642 ENSCANP00000019642 NOTCH3 NOTCH3 ENSCANP00000019087 ENSCANP00000019087 EGF EGF APH1B APH1B EGFR EGFR WWP2 WWP2 ENSCANP00000017238 ENSCANP00000017238 LOC105503496 LOC105503496 JAG2 JAG2 DLL4 DLL4 LOC105523183 LOC105523183 UBA52 UBA52 ENSCANP00000008732 ENSCANP00000008732 MIB2 MIB2 RPS27A RPS27A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (812 aa)
NCSTNNicastrin. (709 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
NEURL1BNeuralized E3 ubiquitin protein ligase 1B. (324 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1089 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (463 aa)
YBX1CSD_1 domain-containing protein. (275 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
NOTCH3Notch receptor 3. (2021 aa)
ENSCANP00000019087Uncharacterized protein. (298 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (219 aa)
EGFRReceptor protein-tyrosine kinase. (1188 aa)
WWP2E3 ubiquitin-protein ligase. (756 aa)
ENSCANP00000017238CSD_1 domain-containing protein. (323 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1099 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ENSCANP00000008732CSP domain-containing protein. (296 aa)
MIB2Mindbomb E3 ubiquitin protein ligase 2. (939 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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