STRINGSTRING
LRRC74B LRRC74B ENSCANP00000023943 ENSCANP00000023943 MFSD1 MFSD1 ENSCANP00000022288 ENSCANP00000022288 MAP2K4 MAP2K4 PSMD1 PSMD1 PSMD10 PSMD10 UBE2N UBE2N NLRP9 NLRP9 ENSCANP00000020516 ENSCANP00000020516 NFKBIB NFKBIB ENSCANP00000019642 ENSCANP00000019642 MAP3K8 MAP3K8 PSMC4 PSMC4 IRAK1 IRAK1 NLRP6 NLRP6 TOLLIP TOLLIP IRAK2 IRAK2 PSMC3 PSMC3 ENSCANP00000018891 ENSCANP00000018891 TNIP2 TNIP2 PELI1 PELI1 PSMD2 PSMD2 NFKB2 NFKB2 TRAF6 TRAF6 LOC105520631 LOC105520631 ENSCANP00000017387 ENSCANP00000017387 TAB1 TAB1 ENSCANP00000016508 ENSCANP00000016508 MAP3K20 MAP3K20 LOC105503496 LOC105503496 PSME1 PSME1 NKIRAS1 NKIRAS1 PSMB10 PSMB10 PSMA7 PSMA7 PSMA8 PSMA8 LOC105518935 LOC105518935 PSMC6 PSMC6 IL1R1 IL1R1 CCDC71L CCDC71L PSMB6 PSMB6 PSMD12 PSMD12 ENSCANP00000013611 ENSCANP00000013611 PSMA5 PSMA5 VWC2 VWC2 PSMA4 PSMA4 USP14 USP14 CASP8 CASP8 LRRC14 LRRC14 ENSCANP00000012071 ENSCANP00000012071 LOC105523183 LOC105523183 ENSCANP00000011827 ENSCANP00000011827 PSME2 PSME2 PELI3 PELI3 UBA52 UBA52 PSMA1 PSMA1 BTRC BTRC IKBKB IKBKB ENSCANP00000010775 ENSCANP00000010775 ENSCANP00000010057 ENSCANP00000010057 CUL1 CUL1 PSMD5 PSMD5 NOD1 NOD1 ALPK1 ALPK1 LOC105508581 LOC105508581 ENSCANP00000008806 ENSCANP00000008806 PSMB2 PSMB2 N4BP1 N4BP1 ENSCANP00000007912 ENSCANP00000007912 PSMA6 PSMA6 MAP3K3 MAP3K3 TAB3 TAB3 NFKBIA NFKBIA ENSCANP00000007099 ENSCANP00000007099 MAP2K6 MAP2K6 ENSCANP00000006830 ENSCANP00000006830 IL1RAP IL1RAP ENSCANP00000006295 ENSCANP00000006295 PSMB11 PSMB11 PSMD6 PSMD6 CHUK CHUK MAP3K7 MAP3K7 TONSL TONSL ENSCANP00000004759 ENSCANP00000004759 ENSCANP00000004477 ENSCANP00000004477 ENSCANP00000004194 ENSCANP00000004194 IRAK3 IRAK3 LRRC31 LRRC31 LOC105515808 LOC105515808 RBX1 RBX1 LOC105516879 LOC105516879 LOC105509542 LOC105509542 MAP3K2 MAP3K2 TIFA TIFA LOC105517114 LOC105517114 ENSCANP00000001894 ENSCANP00000001894 LRRC74A LRRC74A LOC105501700 LOC105501700 LOC105521899 LOC105521899 LOC105513286 LOC105513286 ENSCANP00000000485 ENSCANP00000000485 ENSCANP00000000468 ENSCANP00000000468 PSME3 PSME3 RPS27A RPS27A LRRC34 LRRC34 PSMB7 PSMB7 LOC105508356 LOC105508356 PSMD3 PSMD3 PSMD9 PSMD9 ENSCANP00000039354 ENSCANP00000039354 KHNYN KHNYN TRAF2 TRAF2 LOC105508582 LOC105508582 PSMD13 PSMD13 LOC105508579 LOC105508579 PSMC5 PSMC5 PSMD14 PSMD14 PSMB5 PSMB5 NLRX1 NLRX1 IKBKG IKBKG ENSCANP00000036083 ENSCANP00000036083 HMGB1 HMGB1 IL1RN IL1RN PSMB9 PSMB9 MAP2K1 MAP2K1 IL1A IL1A NLRC5 NLRC5 ENSCANP00000033944 ENSCANP00000033944 LOC105504558 LOC105504558 LRRC71 LRRC71 RELA RELA S100B S100B SQSTM1 SQSTM1 PSMC2 PSMC2 ENSCANP00000032549 ENSCANP00000032549 PSMD7 PSMD7 PSMA3 PSMA3 PSMD4 PSMD4 APP APP LRRC45 LRRC45 FBXW11 FBXW11 RIPK2 RIPK2 IL1B IL1B MYD88 MYD88 PELI2 PELI2 PSMB4 PSMB4 IRAK4 IRAK4 PSME4 PSME4 LOC105500584 LOC105500584 NOD2 NOD2 LOC105520745 LOC105520745 PSMA2 PSMA2 LOC105521476 LOC105521476 UBE2NL UBE2NL TP53 TP53 LOC105525747 LOC105525747 SKP1 SKP1 PSMB1 PSMB1 PSMF1 PSMF1 LOC105520594 LOC105520594 PSMB8 PSMB8 TAB2 TAB2 ENSCANP00000026188 ENSCANP00000026188 ENSCANP00000025859 ENSCANP00000025859 ENSCANP00000025746 ENSCANP00000025746 NLRP13 NLRP13 IL1R2 IL1R2 AGER AGER PSMD11 PSMD11 PSMD8 PSMD8 NFKB1 NFKB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRC74BLeucine rich repeat containing 74B. (366 aa)
ENSCANP00000023943Proteasome subunit beta. (204 aa)
MFSD1Major facilitator superfamily domain containing 1. (465 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (373 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
NLRP9NLR family pyrin domain containing 9. (876 aa)
ENSCANP00000020516CSN8_PSD8_EIF3K domain-containing protein. (254 aa)
NFKBIBNFKB inhibitor beta. (321 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (648 aa)
NLRP6NLR family pyrin domain containing 6. (1041 aa)
TOLLIPToll interacting protein. (272 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (625 aa)
PSMC3AAA domain-containing protein; Belongs to the AAA ATPase family. (439 aa)
ENSCANP00000018891Uncharacterized protein; Belongs to the SKP1 family. (137 aa)
TNIP2TNFAIP3 interacting protein 2. (322 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (747 aa)
NFKB2Nuclear factor kappa B subunit 2. (900 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
LOC105520631UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa)
ENSCANP00000017387Proteasome subunit beta. (181 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
ENSCANP00000016508JAB_MPN domain-containing protein. (167 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
PSME1Proteasome activator subunit 1. (247 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (192 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMA7Proteasome endopeptidase complex. (178 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
LOC105518935AAA domain-containing protein; Belongs to the AAA ATPase family. (426 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
CCDC71LUncharacterized protein. (307 aa)
PSMB6Proteasome subunit beta. (245 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSCANP00000013611AAA domain-containing protein. (371 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (490 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (538 aa)
LRRC14Leucine rich repeat containing 14. (493 aa)
ENSCANP00000012071Uncharacterized protein. (157 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
ENSCANP00000011827Uncharacterized protein. (106 aa)
PSME2Proteasome activator subunit 2. (255 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (527 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
ENSCANP00000010775ATPase_AAA_core domain-containing protein. (385 aa)
ENSCANP00000010057AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
ALPK1Alpha kinase 1. (1244 aa)
LOC105508581Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (121 aa)
ENSCANP00000008806Uncharacterized protein. (357 aa)
PSMB2Proteasome subunit beta. (201 aa)
N4BP1NEDD4 binding protein 1. (829 aa)
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (657 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
ENSCANP00000007099Uncharacterized protein. (213 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ENSCANP00000006830Protein kinase domain-containing protein. (373 aa)
IL1RAPInterleukin 1 receptor accessory protein. (687 aa)
ENSCANP00000006295ANK_REP_REGION domain-containing protein. (151 aa)
PSMB11Proteasome subunit beta. (300 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
TONSLTonsoku like, DNA repair protein. (1240 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
ENSCANP00000004477Uncharacterized protein. (192 aa)
ENSCANP00000004194CCHC NOA-type domain-containing protein. (374 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (553 aa)
LRRC31Leucine rich repeat containing 31. (552 aa)
LOC105515808UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
RBX1Ring-box 1. (108 aa)
LOC105516879Proteasome endopeptidase complex. (214 aa)
LOC105509542UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (639 aa)
TIFATRAF interacting protein with forkhead associated domain. (185 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
ENSCANP00000001894Uncharacterized protein. (215 aa)
LRRC74ALeucine rich repeat containing 74A. (488 aa)
LOC105501700UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
LOC105513286UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
ENSCANP00000000468ATPase_AAA_core domain-containing protein. (421 aa)
PSME3Proteasome activator subunit 3. (170 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
LRRC34Leucine rich repeat containing 34. (415 aa)
PSMB7Proteasome subunit beta. (277 aa)
LOC105508356PCI domain-containing protein. (411 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMD9PDZ domain-containing protein. (223 aa)
ENSCANP00000039354Protein kinase domain-containing protein. (353 aa)
KHNYNKH and NYN domain containing. (678 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
LOC105508582Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (399 aa)
LOC105508579Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMB5Proteasome subunit beta. (263 aa)
NLRX1NLR family member X1. (972 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (369 aa)
ENSCANP00000036083Uncharacterized protein. (111 aa)
HMGB1Uncharacterized protein. (206 aa)
IL1RNInterleukin-1. (159 aa)
PSMB9Proteasome subunit beta 9. (177 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (271 aa)
NLRC5NLR family CARD domain containing 5. (1866 aa)
ENSCANP00000033944Uncharacterized protein; Belongs to the SKP1 family. (131 aa)
LOC105504558UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa)
LRRC71Leucine rich repeat containing 71. (559 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
S100BS_100 domain-containing protein; Belongs to the S-100 family. (94 aa)
SQSTM1Sequestosome 1. (440 aa)
PSMC2AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
ENSCANP00000032549AAA_lid_3 domain-containing protein. (354 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (380 aa)
APPAmyloid beta precursor protein. (770 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
FBXW11F-box and WD repeat domain containing 11. (542 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa)
PELI2Pellino E3 ubiquitin protein ligase family member 2. (394 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (438 aa)
PSME4Proteasome activator subunit 4. (1844 aa)
LOC105500584Uncharacterized protein. (180 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
LOC105520745AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
LOC10552147626S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (834 aa)
UBE2NLUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa)
LOC105525747UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
LOC105520594AAA domain-containing protein; Belongs to the AAA ATPase family. (442 aa)
PSMB8Proteasome subunit beta. (284 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
ENSCANP00000026188AAA domain-containing protein; Belongs to the AAA ATPase family. (430 aa)
ENSCANP00000025859UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa)
ENSCANP00000025746Uncharacterized protein; Belongs to the SKP1 family. (167 aa)
NLRP13NLR family pyrin domain containing 13. (1021 aa)
IL1R2Interleukin 1 receptor type 2. (397 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (410 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
NFKB1Nuclear factor kappa B subunit 1. (970 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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