STRINGSTRING
JUNB JUNB ID1 ID1 FOSB FOSB TCF12 TCF12 EGR1 EGR1 REST REST FOSL1 FOSL1 EGR4 EGR4 EGR2 EGR2 ID2 ID2 ENSCANP00000030238 ENSCANP00000030238 DNM2 DNM2 SGK1 SGK1 SRF SRF ASCL1 ASCL1 CHD4 CHD4 MEF2D MEF2D LYL1 LYL1 TRIB2 TRIB2 ENSCANP00000020706 ENSCANP00000020706 RRAD RRAD CDK5 CDK5 NAB2 NAB2 TRIB1 TRIB1 FOS FOS ID3 ID3 EGR3 EGR3 EP300 EP300 CREB1 CREB1 TPH1 TPH1 SH3GL3 SH3GL3 ATF1 ATF1 ELK1 ELK1 ATF2 ATF2 ARC ARC CDK5R1 CDK5R1 LOC105507704 LOC105507704 NAB1 NAB1 F3 F3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
TCF12Transcription factor 12. (706 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (527 aa)
RESTRE1 silencing transcription factor. (1096 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
EGR4Early growth response 4. (589 aa)
EGR2Early growth response 2. (476 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
ENSCANP00000030238Uncharacterized protein. (315 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (840 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (500 aa)
SRFSerum response factor. (406 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (231 aa)
CHD4Uncharacterized protein. (1882 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
LYL1LYL1 basic helix-loop-helix family member. (280 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
ENSCANP00000020706Protein kinase domain-containing protein. (281 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (302 aa)
NAB2NGFI-A binding protein 2. (525 aa)
TRIB1Tribbles pseudokinase 1. (206 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
EGR3Early growth response 3. (387 aa)
EP300E1A binding protein p300. (2409 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (354 aa)
ATF1Activating transcription factor 1. (270 aa)
ELK1ETS domain-containing protein. (428 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ARCActivity regulated cytoskeleton associated protein. (396 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
LOC105507704ETS domain-containing protein. (403 aa)
NAB1NGFI-A binding protein 1. (487 aa)
F3Coagulation factor III, tissue factor. (296 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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