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MDP1 MDP1 RPS27A RPS27A ENSCANP00000000485 ENSCANP00000000485 LOC105521899 LOC105521899 ZFYVE19 ZFYVE19 LOC105517114 LOC105517114 UBAP1L UBAP1L CHMP6 CHMP6 CHMP5 CHMP5 VPS4A VPS4A ENSCANP00000004759 ENSCANP00000004759 VPS37B VPS37B VPS37C VPS37C C17orf75 C17orf75 ENSCANP00000007912 ENSCANP00000007912 ENSCANP00000008429 ENSCANP00000008429 VPS4B VPS4B UBAP1 UBAP1 UBA52 UBA52 LOC105523183 LOC105523183 TSG101 TSG101 CHMP4A CHMP4A VPS37D VPS37D VPS28 VPS28 STAM2 STAM2 VPS25 VPS25 ENSCANP00000015091 ENSCANP00000015091 VPS36 VPS36 ENSCANP00000016306 ENSCANP00000016306 LOC105503496 LOC105503496 STAM STAM VPS37A VPS37A CHMP4C CHMP4C ENSCANP00000019642 ENSCANP00000019642 CHMP3 CHMP3 CHMP2B CHMP2B ENSCANP00000022288 ENSCANP00000022288 CHMP2A CHMP2A SNF8 SNF8 VTA1 VTA1 LOC105525885 LOC105525885 CHMP4B CHMP4B ENSCANP00000029291 ENSCANP00000029291 CHMP7 CHMP7 HGS HGS ZFYVE1 ZFYVE1 MVB12A MVB12A MVB12B MVB12B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MDP1Magnesium dependent phosphatase 1. (164 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
ZFYVE19Zinc finger FYVE-type containing 19. (462 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
UBAP1LUbiquitin associated protein 1 like. (380 aa)
CHMP6Charged multivesicular body protein 6. (221 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (450 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
VPS37BVPS37B subunit of ESCRT-I. (285 aa)
VPS37CVPS37C subunit of ESCRT-I. (184 aa)
C17orf75Chromosome 17 open reading frame 75. (402 aa)
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
ENSCANP00000008429Uncharacterized protein. (276 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (383 aa)
UBAP1Ubiquitin associated protein 1. (566 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
TSG101Tumor susceptibility 101. (390 aa)
CHMP4ATransmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (815 aa)
VPS37DVPS37D subunit of ESCRT-I. (205 aa)
VPS28VPS28 subunit of ESCRT-I; Belongs to the VPS28 family. (238 aa)
STAM2Signal transducing adaptor molecule 2. (525 aa)
VPS25Vacuolar protein sorting 25 homolog. (176 aa)
ENSCANP00000015091Uncharacterized protein. (167 aa)
VPS36Vacuolar protein sorting 36 homolog. (334 aa)
ENSCANP00000016306VPS37 C-terminal domain-containing protein. (296 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
STAMSignal transducing adaptor molecule. (540 aa)
VPS37AVPS37A subunit of ESCRT-I. (397 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
CHMP3Charged multivesicular body protein 3. (221 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (233 aa)
VTA1Vesicle trafficking 1. (310 aa)
LOC105525885Uncharacterized protein. (226 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
ENSCANP00000029291Uncharacterized protein. (212 aa)
CHMP7Charged multivesicular body protein 7. (453 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (716 aa)
MVB12AMultivesicular body subunit 12A. (273 aa)
MVB12BMultivesicular body subunit 12B. (292 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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