16 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105517114	Ubiquitin-like domain-containing protein. (156 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	LOC105505526	LMWPc domain-containing protein. (152 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	CORO2A	Coronin; Belongs to the WD repeat coronin family. (525 aa)
	HGS	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
	RAB7A	RAB7A, member RAS oncogene family. (207 aa)
	CORO1B	Coronin; Belongs to the WD repeat coronin family. (489 aa)
	CORO1A	Coronin; Belongs to the WD repeat coronin family. (461 aa)
	LOC105503496	Ubiquitin-like domain-containing protein. (147 aa)
	CORO1C	Coronin; Belongs to the WD repeat coronin family. (527 aa)
	ENSCANP00000019642	Ribosomal_S27 domain-containing protein. (93 aa)
	VPS33B	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (610 aa)
	CORO2B	Coronin; Belongs to the WD repeat coronin family. (502 aa)
	CORO6	Coronin; Belongs to the WD repeat coronin family. (472 aa)
	ACP1	LMWPc domain-containing protein. (158 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CORO1A	CORO1B	ENSCANP00000012449	ENSCANP00000040085	Coronin; Belongs to the WD repeat coronin family.	Coronin; Belongs to the WD repeat coronin family.	0.662
CORO1B	CORO1A	ENSCANP00000040085	ENSCANP00000012449	Coronin; Belongs to the WD repeat coronin family.	Coronin; Belongs to the WD repeat coronin family.	0.662
CORO1B	CORO1C	ENSCANP00000040085	ENSCANP00000019620	Coronin; Belongs to the WD repeat coronin family.	Coronin; Belongs to the WD repeat coronin family.	0.816
CORO1B	CORO6	ENSCANP00000040085	ENSCANP00000023848	Coronin; Belongs to the WD repeat coronin family.	Coronin; Belongs to the WD repeat coronin family.	0.632
CORO1C	CORO1B	ENSCANP00000019620	ENSCANP00000040085	Coronin; Belongs to the WD repeat coronin family.	Coronin; Belongs to the WD repeat coronin family.	0.816
CORO6	CORO1B	ENSCANP00000023848	ENSCANP00000040085	Coronin; Belongs to the WD repeat coronin family.	Coronin; Belongs to the WD repeat coronin family.	0.632
ENSCANP00000019642	HGS	ENSCANP00000019642	ENSCANP00000033911	Ribosomal_S27 domain-containing protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.881
ENSCANP00000019642	UBA52	ENSCANP00000019642	ENSCANP00000011352	Ribosomal_S27 domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.988
HGS	ENSCANP00000019642	ENSCANP00000033911	ENSCANP00000019642	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Ribosomal_S27 domain-containing protein.	0.881
HGS	LOC105503496	ENSCANP00000033911	ENSCANP00000016322	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Ubiquitin-like domain-containing protein.	0.881
HGS	LOC105517114	ENSCANP00000033911	ENSCANP00000002234	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Ubiquitin-like domain-containing protein.	0.881
HGS	RPS27A	ENSCANP00000033911	ENSCANP00000000407	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Ubiquitin-like domain-containing protein.	0.881
HGS	UBA52	ENSCANP00000033911	ENSCANP00000011352	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.651
LOC105503496	HGS	ENSCANP00000016322	ENSCANP00000033911	Ubiquitin-like domain-containing protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.881
LOC105503496	UBA52	ENSCANP00000016322	ENSCANP00000011352	Ubiquitin-like domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.962
LOC105517114	HGS	ENSCANP00000002234	ENSCANP00000033911	Ubiquitin-like domain-containing protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.881
LOC105517114	UBA52	ENSCANP00000002234	ENSCANP00000011352	Ubiquitin-like domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.962
RPS27A	HGS	ENSCANP00000000407	ENSCANP00000033911	Ubiquitin-like domain-containing protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.881
RPS27A	UBA52	ENSCANP00000000407	ENSCANP00000011352	Ubiquitin-like domain-containing protein.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.962
UBA52	ENSCANP00000019642	ENSCANP00000011352	ENSCANP00000019642	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Ribosomal_S27 domain-containing protein.	0.988