23 items (Colobus angolensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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protein homology

Your Input:
	ENSCANP00000007912	Ubiquitin-like domain-containing protein. (121 aa)
	LOC105523183	Ubiquitin-like domain-containing protein. (77 aa)
	LOC105503496	Ubiquitin-like domain-containing protein. (147 aa)
	TICAM2	Toll like receptor adaptor molecule 2. (235 aa)
	TLR4	Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	ENSCANP00000000485	Ubiquitin-like domain-containing protein. (72 aa)
	LOC105521899	Ubiquitin-like domain-containing protein. (146 aa)
	LY96	Lymphocyte antigen 96. (160 aa)
	IRAK2	Interleukin 1 receptor associated kinase 2. (625 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
	TAB1	TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
	MAP3K20	Mitogen-activated protein kinase kinase kinase 20. (800 aa)
	LOC105517114	Ubiquitin-like domain-containing protein. (156 aa)
	ENSCANP00000004759	Ubiquitin-like domain-containing protein. (147 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
	TAB3	TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	CD14	Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa)
	TICAM1	Toll like receptor adaptor molecule 1. (517 aa)
	TAB2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
	ENSCANP00000022288	Ubiquitin-like domain-containing protein. (79 aa)
	ENSCANP00000019642	Ribosomal_S27 domain-containing protein. (93 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD14	LY96	ENSCANP00000028873	ENSCANP00000019604	Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...]	Lymphocyte antigen 96.	0.929
CD14	TLR4	ENSCANP00000028873	ENSCANP00000028903	Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...]	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.965
CD14	TRAF6	ENSCANP00000028873	ENSCANP00000017842	Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...]	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.411
ENSCANP00000000485	ENSCANP00000019642	ENSCANP00000000485	ENSCANP00000019642	Ubiquitin-like domain-containing protein.	Ribosomal_S27 domain-containing protein.	0.891
ENSCANP00000000485	LOC105503496	ENSCANP00000000485	ENSCANP00000016322	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.892
ENSCANP00000000485	LOC105517114	ENSCANP00000000485	ENSCANP00000002234	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.892
ENSCANP00000000485	LOC105523183	ENSCANP00000000485	ENSCANP00000011982	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.910
ENSCANP00000000485	MAP3K20	ENSCANP00000000485	ENSCANP00000016355	Ubiquitin-like domain-containing protein.	Mitogen-activated protein kinase kinase kinase 20.	0.404
ENSCANP00000000485	MAP3K7	ENSCANP00000000485	ENSCANP00000005130	Ubiquitin-like domain-containing protein.	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.	0.419
ENSCANP00000000485	RPS27A	ENSCANP00000000485	ENSCANP00000000407	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.892
ENSCANP00000000485	TAB2	ENSCANP00000000485	ENSCANP00000026565	Ubiquitin-like domain-containing protein.	TGF-beta activated kinase 1 (MAP3K7) binding protein 2.	0.703
ENSCANP00000000485	TAB3	ENSCANP00000000485	ENSCANP00000007529	Ubiquitin-like domain-containing protein.	TGF-beta activated kinase 1 (MAP3K7) binding protein 3.	0.552
ENSCANP00000000485	TRAF6	ENSCANP00000000485	ENSCANP00000017842	Ubiquitin-like domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.808
ENSCANP00000004759	ENSCANP00000019642	ENSCANP00000004759	ENSCANP00000019642	Ubiquitin-like domain-containing protein.	Ribosomal_S27 domain-containing protein.	0.952
ENSCANP00000004759	LOC105503496	ENSCANP00000004759	ENSCANP00000016322	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.953
ENSCANP00000004759	LOC105517114	ENSCANP00000004759	ENSCANP00000002234	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.953
ENSCANP00000004759	LOC105521899	ENSCANP00000004759	ENSCANP00000000599	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.545
ENSCANP00000004759	LOC105523183	ENSCANP00000004759	ENSCANP00000011982	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.910
ENSCANP00000004759	MAP3K20	ENSCANP00000004759	ENSCANP00000016355	Ubiquitin-like domain-containing protein.	Mitogen-activated protein kinase kinase kinase 20.	0.404
ENSCANP00000004759	MAP3K7	ENSCANP00000004759	ENSCANP00000005130	Ubiquitin-like domain-containing protein.	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.	0.419