(39 nodes) KR domain network (Colobus angolensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RDH8	Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
	HSD3B1	Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (373 aa)
	HSD17B1	Hydroxysteroid 17-beta dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (320 aa)
	HPGD	15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
	BDH1	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)
	LOC105517486	Carbonyl reductase 1. (222 aa)
	RDH13	Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
	HSD17B14	Hydroxysteroid 17-beta dehydrogenase 14. (270 aa)
	DECR1	2,4-dienoyl-CoA reductase 1. (335 aa)
	DHRS7	Dehydrogenase/reductase 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (339 aa)
	HSDL1	Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa)
	RDH12	Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
	HSD11B1	Hydroxysteroid 11-beta dehydrogenase 1. (292 aa)
	HSD17B11	Hydroxysteroid 17-beta dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
	KDSR	3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (324 aa)
	DHRSX	Dehydrogenase/reductase X-linked; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (293 aa)
	DHRS11	Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
	WWOX	WW domain containing oxidoreductase. (414 aa)
	SDR16C5	Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
	GALE	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa)
	LOC105503748	Uncharacterized protein. (278 aa)
	DHRS2	Dehydrogenase/reductase 2. (280 aa)
	HSD3B7	Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. (369 aa)
	DHRS3	Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
	HSD17B13	Hydroxysteroid 17-beta dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
	DCXR	Dicarbonyl and L-xylulose reductase. (244 aa)
	CBR4	Uncharacterized protein. (237 aa)
	HSD17B8	Hydroxysteroid 17-beta dehydrogenase 8. (261 aa)
	HSDL2	Hydroxysteroid dehydrogenase like 2. (349 aa)
	DHRS1	Dehydrogenase/reductase 1. (313 aa)
	HSD17B10	Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
	PECR	Peroxisomal trans-2-enoyl-CoA reductase. (303 aa)
	HSD17B7	Hydroxysteroid 17-beta dehydrogenase 7. (366 aa)
	CBR3	Carbonyl reductase 3. (241 aa)
	DECR2	2,4-dienoyl-CoA reductase 2. (363 aa)
	LOC105503750	Uncharacterized protein. (278 aa)
	HSD17B12	Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (308 aa)
	RDH11	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
	DHRS7B	Dehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDH1	DECR2	ENSCANP00000003836	ENSCANP00000016662	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	2,4-dienoyl-CoA reductase 2.	0.404
BDH1	DHRS11	ENSCANP00000003836	ENSCANP00000026318	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.463
BDH1	HSD11B1	ENSCANP00000003836	ENSCANP00000022269	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Hydroxysteroid 11-beta dehydrogenase 1.	0.501
BDH1	HSD17B7	ENSCANP00000003836	ENSCANP00000013111	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Hydroxysteroid 17-beta dehydrogenase 7.	0.465
BDH1	HSD17B8	ENSCANP00000003836	ENSCANP00000040379	3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Hydroxysteroid 17-beta dehydrogenase 8.	0.431
CBR3	DCXR	ENSCANP00000016197	ENSCANP00000038286	Carbonyl reductase 3.	Dicarbonyl and L-xylulose reductase.	0.692
CBR3	HSDL2	ENSCANP00000016197	ENSCANP00000009936	Carbonyl reductase 3.	Hydroxysteroid dehydrogenase like 2.	0.414
CBR3	LOC105517486	ENSCANP00000016197	ENSCANP00000004215	Carbonyl reductase 3.	Carbonyl reductase 1.	0.562
CBR4	DHRS2	ENSCANP00000040047	ENSCANP00000030172	Uncharacterized protein.	Dehydrogenase/reductase 2.	0.437
CBR4	HSD17B12	ENSCANP00000040047	ENSCANP00000018325	Uncharacterized protein.	Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.424
CBR4	HSD17B7	ENSCANP00000040047	ENSCANP00000013111	Uncharacterized protein.	Hydroxysteroid 17-beta dehydrogenase 7.	0.431
CBR4	HSD17B8	ENSCANP00000040047	ENSCANP00000040379	Uncharacterized protein.	Hydroxysteroid 17-beta dehydrogenase 8.	0.952
CBR4	HSDL1	ENSCANP00000040047	ENSCANP00000007159	Uncharacterized protein.	Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.413
CBR4	HSDL2	ENSCANP00000040047	ENSCANP00000009936	Uncharacterized protein.	Hydroxysteroid dehydrogenase like 2.	0.482
CBR4	LOC105503748	ENSCANP00000040047	ENSCANP00000029635	Uncharacterized protein.	Uncharacterized protein.	0.423
CBR4	LOC105503750	ENSCANP00000040047	ENSCANP00000017128	Uncharacterized protein.	Uncharacterized protein.	0.422
DCXR	CBR3	ENSCANP00000038286	ENSCANP00000016197	Dicarbonyl and L-xylulose reductase.	Carbonyl reductase 3.	0.692
DCXR	LOC105517486	ENSCANP00000038286	ENSCANP00000004215	Dicarbonyl and L-xylulose reductase.	Carbonyl reductase 1.	0.692
DECR1	HSD17B12	ENSCANP00000006006	ENSCANP00000018325	2,4-dienoyl-CoA reductase 1.	Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.463
DECR1	HSD17B8	ENSCANP00000006006	ENSCANP00000040379	2,4-dienoyl-CoA reductase 1.	Hydroxysteroid 17-beta dehydrogenase 8.	0.414