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| | ELOVL7 | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa) |
| | MECR | Mitochondrial trans-2-enoyl-CoA reductase. (373 aa) |
| | TECR | Trans-2,3-enoyl-CoA reductase. (315 aa) |
| | OXSM | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa) |
| | SUGCT | Uncharacterized protein. (378 aa) |
| | ACADSB | Acyl-CoA dehydrogenase short/branched chain. (432 aa) |
| | IQCA1L | IQ motif containing with AAA domain 1 like. (819 aa) |
| | HACD3 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (400 aa) |
| | ACSBG1 | Acyl-CoA synthetase bubblegum family member 1. (723 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein. (326 aa) |
| | EHHADH | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. (627 aa) |
| | ACSF2 | Acyl-CoA synthetase family member 2. (618 aa) |
| | HADHA | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa) |
| | ELOVL3 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa) |
| | SCD | Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa) |
| | ECHS1 | Enoyl-CoA hydratase, short chain 1. (270 aa) |
| | CPT2 | Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (658 aa) |
| | HADHB | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa) |
| | ELOVL1 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (279 aa) |
| | LOC105527263 | Cytochrome b5 heme-binding domain-containing protein. (482 aa) |
| | MCAT | Malonyl-CoA-acyl carrier protein transacylase. (219 aa) |
| | SCD5 | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (267 aa) |
| | HSD17B8 | Hydroxysteroid 17-beta dehydrogenase 8. (261 aa) |
| | BSN | Bassoon presynaptic cytomatrix protein. (3900 aa) |
| | SLTM | SAFB like transcription modulator. (979 aa) |
| | CBR4 | Uncharacterized protein. (237 aa) |
| | FADS2 | Fatty acid desaturase 2. (444 aa) |
| | FADS3 | Fatty acid desaturase 3. (442 aa) |
| | ELOVL2 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (295 aa) |
| | FADS1 | Fatty acid desaturase 1. (501 aa) |
| | FASN | Fatty acid synthase. (2510 aa) |
| | HACD4 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (232 aa) |
| | ELOVL4 | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa) |
| | CPT1A | Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa) |
| | ACSBG2 | Acyl-CoA synthetase bubblegum family member 2. (665 aa) |
| | ACSL4 | Acyl-CoA synthetase long chain family member 4. (711 aa) |
| | HTD2 | Hydroxyacyl-thioester dehydratase type 2. (162 aa) |
| | ACAD9 | Acyl-CoA dehydrogenase family member 9. (621 aa) |
| | ACSL1 | Acyl-CoA synthetase long chain family member 1. (698 aa) |
| | ACAT1 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa) |
| | CARTPT | CART prepropeptide. (116 aa) |
| | CPT1C | Carnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (803 aa) |
| | HSD17B4 | Hydroxysteroid 17-beta dehydrogenase 4. (754 aa) |
| | ACSL5 | Acyl-CoA synthetase long chain family member 5. (723 aa) |
| | LOC105510487 | Uncharacterized protein. (408 aa) |
| | ACAA1 | Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa) |
| | HACD2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (227 aa) |
| | HADH | Hydroxyacyl-CoA dehydrogenase. (382 aa) |
| | PPT2 | Palmitoyl-protein thioesterase 2. (309 aa) |
| | ACADS | Acyl-CoA dehydrogenase short chain. (412 aa) |
| | SCP2 | Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa) |
| | IQCA1 | IQ motif containing with AAA domain 1. (845 aa) |
| | HSDL1 | Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | ACOX1 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (660 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2383 aa) |
| | ACAA2 | Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | CPT1B | Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa) |
| | ACSL6 | AMP-binding domain-containing protein. (722 aa) |
| | HSDL2 | Hydroxysteroid dehydrogenase like 2. (349 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | PPT1 | Palmitoyl-protein thioesterase 1. (335 aa) |
| | C15orf41 | Chromosome 15 open reading frame 41. (281 aa) |
| | ACADL | Acyl-CoA dehydrogenase long chain. (419 aa) |
| | ACSF3 | Acyl-CoA synthetase family member 3. (576 aa) |
| | PGGT1B | Protein geranylgeranyltransferase type I subunit beta. (377 aa) |
| | TECRL | Trans-2,3-enoyl-CoA reductase like. (363 aa) |
| | ACADM | Acyl-CoA dehydrogenase medium chain. (454 aa) |
| | ACSL3 | Acyl-CoA synthetase long chain family member 3. (720 aa) |
| | ACAT2 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) |
| | HSD17B12 | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (308 aa) |
| | ACOX3 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa) |
| | LOC105510727 | Uncharacterized protein. (228 aa) |
| | ACADVL | Acyl-CoA dehydrogenase very long chain. (677 aa) |
| | LOC105523268 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (456 aa) |
| | ENSCANP00000022864 | Uncharacterized protein. (666 aa) |
| | MDM2 | MDM2 proto-oncogene. (513 aa) |
| | RPP14 | Ribonuclease P/MRP subunit p14. (124 aa) |
| | LOC105524409 | Uncharacterized protein. (718 aa) |
| | ENSCANP00000022299 | Uncharacterized protein. (259 aa) |
