(40 nodes) Protein export network (Colobus angolensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SEC61A2	SEC61 translocon alpha 2 subunit. (473 aa)
	LOC105526708	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. (86 aa)
	LOC105501754	Uncharacterized protein. (135 aa)
	YPEL2	Protein yippee-like; Belongs to the yippee family. (119 aa)
	SEC11C	Signal peptidase complex catalytic subunit SEC11. (192 aa)
	SEC61G	SEC61 translocon gamma subunit. (68 aa)
	SEC63	SEC63 homolog, protein translocation regulator. (726 aa)
	YPEL3	Protein yippee-like; Belongs to the yippee family. (157 aa)
	ENSCANP00000020123	Uncharacterized protein. (142 aa)
	SEC61A1	SEC61 translocon alpha 1 subunit. (569 aa)
	SRPRA	SRP receptor subunit alpha. (638 aa)
	SRP54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (515 aa)
	SEC61B	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
	LOC105515685	Uncharacterized protein. (483 aa)
	TMEM19	Transmembrane protein 19. (336 aa)
	ENSCANP00000028846	SRP72 domain-containing protein. (538 aa)
	ITFG2	Integrin alpha FG-GAP repeat containing 2. (447 aa)
	SRP14	Signal recognition particle 14. (141 aa)
	SPCS3	Signal peptidase complex subunit 3. (132 aa)
	LOC105521187	Uncharacterized protein; Belongs to the heat shock protein 70 family. (546 aa)
	SRP9	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. (86 aa)
	YPEL5	Protein yippee-like; Belongs to the yippee family. (121 aa)
	IMMP2L	Inner mitochondrial membrane peptidase subunit 2. (95 aa)
	SPCS2	Signal peptidase complex subunit 2. (257 aa)
	SPCS1	Signal peptidase complex subunit 1. (169 aa)
	ANKRD45	ANK_REP_REGION domain-containing protein. (264 aa)
	LOC105521660	Uncharacterized protein. (80 aa)
	SRP68	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (597 aa)
	IMMP1L	Mitochondrial inner membrane protease subunit. (166 aa)
	SEC11A	SEC11 homolog A, signal peptidase complex subunit. (129 aa)
	SRP19	Uncharacterized protein. (120 aa)
	ENSCANP00000026458	Plug_translocon domain-containing protein. (123 aa)
	YPEL4	Protein yippee-like; Belongs to the yippee family. (127 aa)
	SEC62	SEC62 homolog, preprotein translocation factor. (399 aa)
	HSPA5	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
	SRP72	Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (671 aa)
	YPEL1	Protein yippee-like; Belongs to the yippee family. (119 aa)
	ENSCANP00000037244	Uncharacterized protein. (186 aa)
	OXA1L	Uncharacterized protein. (438 aa)
	SRPRB	SRP receptor subunit beta. (224 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD45	ENSCANP00000020123	ENSCANP00000006339	ENSCANP00000020123	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.437
ANKRD45	ENSCANP00000026458	ENSCANP00000006339	ENSCANP00000026458	ANK_REP_REGION domain-containing protein.	Plug_translocon domain-containing protein.	0.460
ANKRD45	ENSCANP00000037244	ENSCANP00000006339	ENSCANP00000037244	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.437
ANKRD45	SEC61A1	ENSCANP00000006339	ENSCANP00000019427	ANK_REP_REGION domain-containing protein.	SEC61 translocon alpha 1 subunit.	0.460
ANKRD45	SEC61A2	ENSCANP00000006339	ENSCANP00000003663	ANK_REP_REGION domain-containing protein.	SEC61 translocon alpha 2 subunit.	0.460
ANKRD45	SEC61B	ENSCANP00000006339	ENSCANP00000025553	ANK_REP_REGION domain-containing protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.404
ANKRD45	SEC62	ENSCANP00000006339	ENSCANP00000035080	ANK_REP_REGION domain-containing protein.	SEC62 homolog, preprotein translocation factor.	0.421
ANKRD45	SEC63	ENSCANP00000006339	ENSCANP00000021477	ANK_REP_REGION domain-containing protein.	SEC63 homolog, protein translocation regulator.	0.928
ANKRD45	SPCS2	ENSCANP00000006339	ENSCANP00000011570	ANK_REP_REGION domain-containing protein.	Signal peptidase complex subunit 2.	0.437
ENSCANP00000020123	ANKRD45	ENSCANP00000020123	ENSCANP00000006339	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.437
ENSCANP00000020123	HSPA5	ENSCANP00000020123	ENSCANP00000035472	Uncharacterized protein.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.519
ENSCANP00000020123	IMMP1L	ENSCANP00000020123	ENSCANP00000031434	Uncharacterized protein.	Mitochondrial inner membrane protease subunit.	0.684
ENSCANP00000020123	IMMP2L	ENSCANP00000020123	ENSCANP00000012544	Uncharacterized protein.	Inner mitochondrial membrane peptidase subunit 2.	0.684
ENSCANP00000020123	ITFG2	ENSCANP00000020123	ENSCANP00000024663	Uncharacterized protein.	Integrin alpha FG-GAP repeat containing 2.	0.684
ENSCANP00000020123	LOC105521187	ENSCANP00000020123	ENSCANP00000014811	Uncharacterized protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.519
ENSCANP00000020123	LOC105521660	ENSCANP00000020123	ENSCANP00000029094	Uncharacterized protein.	Uncharacterized protein.	0.684
ENSCANP00000020123	SEC11A	ENSCANP00000020123	ENSCANP00000032326	Uncharacterized protein.	SEC11 homolog A, signal peptidase complex subunit.	0.920
ENSCANP00000020123	SEC11C	ENSCANP00000020123	ENSCANP00000021716	Uncharacterized protein.	Signal peptidase complex catalytic subunit SEC11.	0.960
ENSCANP00000020123	SEC61B	ENSCANP00000020123	ENSCANP00000025553	Uncharacterized protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.497
ENSCANP00000020123	SEC62	ENSCANP00000020123	ENSCANP00000035080	Uncharacterized protein.	SEC62 homolog, preprotein translocation factor.	0.539