STRINGSTRING
CAMK2D CAMK2D CAMK2B CAMK2B EGFR EGFR RAF1 RAF1 MAPK10 MAPK10 EGF EGF ENSCANP00000019829 ENSCANP00000019829 MAPK8 MAPK8 RRAD RRAD EREG EREG ENSCANP00000020790 ENSCANP00000020790 PIK3R1 PIK3R1 ARSI ARSI AKT2 AKT2 MTOR MTOR ARAF ARAF MAP2K4 MAP2K4 PRKCB PRKCB CSDE1 CSDE1 SHC1 SHC1 SHC2 SHC2 PAK5 PAK5 PAK3 PAK3 CDKN1B CDKN1B CBLB CBLB CDKN1A CDKN1A MAPK1 MAPK1 SHC3 SHC3 NRG1 NRG1 AKT3 AKT3 MYC MYC PIK3CB PIK3CB CRKL CRKL PAK2 PAK2 JUN JUN ABL2 ABL2 CEP152 CEP152 PIK3R2 PIK3R2 NCK1 NCK1 SOS1 SOS1 ABL1 ABL1 CAMK2G CAMK2G MAP2K1 MAP2K1 PIK3R3 PIK3R3 BRAF BRAF SOS2 SOS2 GAB1 GAB1 PIK3CD PIK3CD EPGN EPGN PTK2 PTK2 PPP1R14B PPP1R14B BTC BTC MSANTD3-TMEFF1 MSANTD3-TMEFF1 NRG3 NRG3 AREG AREG CBL CBL PAK6 PAK6 ENSCANP00000039354 ENSCANP00000039354 GRB2 GRB2 SRC SRC REM1 REM1 TMEFF2 TMEFF2 ERAS ERAS MAP2K7 MAP2K7 PLCG2 PLCG2 PRKCA PRKCA LOC105507704 LOC105507704 SHC4 SHC4 BAD BAD HRAS HRAS RPS6KB2 RPS6KB2 HBEGF HBEGF EIF4EBP1 EIF4EBP1 TGFA TGFA PAK1 PAK1 KRAS KRAS ENSCANP00000006830 ENSCANP00000006830 ELK1 ELK1 ERBB3 ERBB3 ERBB2 ERBB2 ELK3 ELK3 PAK4 PAK4 ENSCANP00000009565 ENSCANP00000009565 PRKCG PRKCG NRG2 NRG2 MAPK9 MAPK9 GSK3B GSK3B PLCG1 PLCG1 NCK2 NCK2 ENSCANP00000012327 ENSCANP00000012327 GEM GEM STAT5A STAT5A ALKBH4 ALKBH4 STAT5B STAT5B MAP2K2 MAP2K2 RPS6KB1 RPS6KB1 ERBB4 ERBB4 CAMK2A CAMK2A AKT1 AKT1 LOC105504658 LOC105504658 MAPK3 MAPK3 PIK3CA PIK3CA CRK CRK NRG4 NRG4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
EGFRReceptor protein-tyrosine kinase. (1188 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
ENSCANP00000019829Uncharacterized protein. (98 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
EREGEpiregulin. (169 aa)
ENSCANP00000020790Uncharacterized protein. (84 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ARSIArylsulfatase family member I. (569 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (587 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (373 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
CSDE1Uncharacterized protein. (844 aa)
SHC1SHC adaptor protein 1. (584 aa)
SHC2SHC adaptor protein 2. (381 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
CBLBCbl proto-oncogene B. (982 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
SHC3SHC adaptor protein 3. (517 aa)
NRG1Neuregulin 1. (645 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
ABL2ABL proto-oncogene 2, non-receptor tyrosine kinase. (850 aa)
CEP152Centrosomal protein 152. (1709 aa)
PIK3R2Uncharacterized protein. (601 aa)
NCK1Cytoplasmic protein. (377 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1310 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (552 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (747 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1071 aa)
EPGNEpithelial mitogen. (154 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (132 aa)
BTCBetacellulin. (178 aa)
MSANTD3-TMEFF1MSANTD3-TMEFF1 readthrough. (454 aa)
NRG3Neuregulin 3. (627 aa)
AREGAmphiregulin. (275 aa)
CBLCbl proto-oncogene. (888 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
ENSCANP00000039354Protein kinase domain-containing protein. (353 aa)
GRB2Uncharacterized protein. (156 aa)
SRCTyrosine-protein kinase. (458 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa)
ERASES cell expressed Ras. (233 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (468 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1257 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
LOC105507704ETS domain-containing protein. (403 aa)
SHC4SHC adaptor protein 4. (630 aa)
BADBCL2 associated agonist of cell death. (167 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (110 aa)
TGFATransforming growth factor alpha. (166 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ENSCANP00000006830Protein kinase domain-containing protein. (373 aa)
ELK1ETS domain-containing protein. (428 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1330 aa)
ERBB2Receptor protein-tyrosine kinase. (1259 aa)
ELK3ETS transcription factor ELK3. (407 aa)
PAK4Non-specific serine/threonine protein kinase. (597 aa)
ENSCANP00000009565Uncharacterized protein. (651 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
NRG2Neuregulin 2. (671 aa)
MAPK9Mitogen-activated protein kinase. (399 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
NCK2Cytoplasmic protein. (380 aa)
ENSCANP00000012327Uncharacterized protein. (178 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
STAT5ASignal transducer and activator of transcription. (789 aa)
ALKBH4AlkB homolog 4, lysine demethylase. (302 aa)
STAT5BSignal transducer and activator of transcription. (756 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (369 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
ERBB4Receptor protein-tyrosine kinase. (1283 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
LOC105504658Uncharacterized protein. (571 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
NRG4Neuregulin 4. (115 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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