STRINGSTRING
MAPK9 MAPK9 SRC SRC ULK1 ULK1 FUNDC1 FUNDC1 LOC105513393 LOC105513393 USP11 USP11 OPTN OPTN PDIK1L PDIK1L RAB7A RAB7A NBR1 NBR1 GABARAPL2 GABARAPL2 HIF3A HIF3A USP19 USP19 RELA RELA RRAS2 RRAS2 SQSTM1 SQSTM1 NPAS3 NPAS3 JUN JUN ATF4 ATF4 TOMM7 TOMM7 E2F1 E2F1 USP43 USP43 ENSCANP00000030691 ENSCANP00000030691 FUNDC2 FUNDC2 TP53 TP53 ENSCANP00000028764 ENSCANP00000028764 GABARAPL1 GABARAPL1 HIF1A HIF1A METTL17 METTL17 TFE3 TFE3 RAB7B RAB7B TBC1D15 TBC1D15 RHOT1 RHOT1 SP1 SP1 PGAM5 PGAM5 GABARAP GABARAP CSNK2B CSNK2B AMBRA1 AMBRA1 ENSCANP00000024401 ENSCANP00000024401 PINK1 PINK1 AGFG1 AGFG1 EIF2AK3 EIF2AK3 ATG5 ATG5 CSDE1 CSDE1 BECN1 BECN1 USP32 USP32 RIT1 RIT1 ENSCANP00000022288 ENSCANP00000022288 SPEN SPEN MFN1 MFN1 CSNK2A2 CSNK2A2 TAX1BP1 TAX1BP1 RRAD RRAD MAPK8 MAPK8 ENSCANP00000019829 ENSCANP00000019829 CITED2 CITED2 ENSCANP00000019642 ENSCANP00000019642 ATG9B ATG9B USP8 USP8 BCL2L13 BCL2L13 RHOT2 RHOT2 MAPK10 MAPK10 USP4 USP4 STK35 STK35 CSNK2A1 CSNK2A1 RASL11B RASL11B MRAS MRAS RIT2 RIT2 LOC105503496 LOC105503496 RRAS RRAS LOC105504658 LOC105504658 MITF MITF AGFG2 AGFG2 TFEB TFEB USP15 USP15 GEM GEM ENSCANP00000012327 ENSCANP00000012327 LOC105523183 LOC105523183 MFN2 MFN2 UBA52 UBA52 ATG9A ATG9A ENSCANP00000010820 ENSCANP00000010820 BNIP3L BNIP3L TFEC TFEC ENSCANP00000008262 ENSCANP00000008262 ENSCANP00000007912 ENSCANP00000007912 BNIP3 BNIP3 FOXO3 FOXO3 ENSCANP00000006631 ENSCANP00000006631 KRAS KRAS HRAS HRAS PRKN PRKN ENSCANP00000004759 ENSCANP00000004759 LOC105508805 LOC105508805 USP30 USP30 LOC105517114 LOC105517114 CALCOCO2 CALCOCO2 ERAS ERAS TBK1 TBK1 FIS1 FIS1 BCL2L1 BCL2L1 LOC105521899 LOC105521899 USP31 USP31 ENSCANP00000000485 ENSCANP00000000485 RPS27A RPS27A REM1 REM1 TBC1D17 TBC1D17
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK9Mitogen-activated protein kinase. (399 aa)
SRCTyrosine-protein kinase. (458 aa)
ULK1Unc-51 like autophagy activating kinase 1. (974 aa)
FUNDC1FUN14 domain containing 1. (155 aa)
LOC105513393Uncharacterized protein. (309 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (980 aa)
OPTNOptineurin. (571 aa)
PDIK1LPDLIM1 interacting kinase 1 like; Belongs to the protein kinase superfamily. (341 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
NBR1NBR1 autophagy cargo receptor. (981 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
HIF3AHypoxia inducible factor 3 subunit alpha. (498 aa)
USP19Ubiquitin specific peptidase 19. (1381 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
RRAS2RAS related 2. (179 aa)
SQSTM1Sequestosome 1. (440 aa)
NPAS3Neuronal PAS domain protein 3. (914 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
ATF4Activating transcription factor 4. (351 aa)
TOMM7Uncharacterized protein. (125 aa)
E2F1E2F transcription factor 1. (436 aa)
USP43Ubiquitin specific peptidase 43. (795 aa)
ENSCANP00000030691Uncharacterized protein. (78 aa)
FUNDC2FUN14 domain containing 2. (189 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa)
ENSCANP00000028764Uncharacterized protein. (183 aa)
GABARAPL1GABA type A receptor associated protein like 1. (146 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (827 aa)
METTL17Methyltransferase like 17. (458 aa)
TFE3Transcription factor binding to IGHM enhancer 3. (575 aa)
RAB7BRAB7B, member RAS oncogene family. (199 aa)
TBC1D15TBC1 domain family member 15. (691 aa)
RHOT1Ras homolog family member T1. (750 aa)
SP1Sp1 transcription factor. (718 aa)
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (239 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
CSNK2BUncharacterized protein. (296 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
ENSCANP00000024401Uncharacterized protein. (135 aa)
PINK1PTEN induced kinase 1. (507 aa)
AGFG1ArfGAP with FG repeats 1. (528 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (965 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
CSDE1Uncharacterized protein. (844 aa)
BECN1Uncharacterized protein. (451 aa)
USP32Uncharacterized protein; Belongs to the peptidase C19 family. (1603 aa)
RIT1Ras like without CAAX 1. (236 aa)
ENSCANP00000022288Ubiquitin-like domain-containing protein. (79 aa)
SPENSpen family transcriptional repressor. (3641 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (696 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (323 aa)
TAX1BP1Tax1 binding protein 1. (813 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSCANP00000019829Uncharacterized protein. (98 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
ENSCANP00000019642Ribosomal_S27 domain-containing protein. (93 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (898 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1118 aa)
BCL2L13BCL2 like 13. (493 aa)
RHOT2Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (605 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (956 aa)
STK35Serine/threonine kinase 35. (419 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
RASL11BRAS like family 11 member B. (248 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
RIT2Uncharacterized protein. (162 aa)
LOC105503496Ubiquitin-like domain-containing protein. (147 aa)
RRASRAS related. (218 aa)
LOC105504658Uncharacterized protein. (571 aa)
MITFMelanocyte inducing transcription factor. (526 aa)
AGFG2ArfGAP with FG repeats 2. (466 aa)
TFEBTranscription factor EB. (490 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
ENSCANP00000012327Uncharacterized protein. (178 aa)
LOC105523183Ubiquitin-like domain-containing protein. (77 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (387 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (852 aa)
ENSCANP00000010820PAS domain-containing protein. (213 aa)
BNIP3LBCL2 interacting protein 3 like. (218 aa)
TFECTranscription factor EC. (347 aa)
ENSCANP00000008262USP8_dimer domain-containing protein. (105 aa)
ENSCANP00000007912Ubiquitin-like domain-containing protein. (121 aa)
BNIP3BCL2 interacting protein 3. (185 aa)
FOXO3Forkhead box O3. (544 aa)
ENSCANP00000006631Uncharacterized protein. (95 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
ENSCANP00000004759Ubiquitin-like domain-containing protein. (147 aa)
LOC105508805Uncharacterized protein. (151 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (501 aa)
LOC105517114Ubiquitin-like domain-containing protein. (156 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (470 aa)
ERASES cell expressed Ras. (233 aa)
TBK1TANK binding kinase 1. (713 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
BCL2L1BCL2 like 1. (233 aa)
LOC105521899Ubiquitin-like domain-containing protein. (146 aa)
USP31Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1233 aa)
ENSCANP00000000485Ubiquitin-like domain-containing protein. (72 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
TBC1D17TBC1 domain family member 17. (597 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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