STRINGSTRING
MYL9 MYL9 PROCA1 PROCA1 GUCY1B1 GUCY1B1 PLA2G1B PLA2G1B ENSCANP00000001976 ENSCANP00000001976 PPP1CA PPP1CA RAMP3 RAMP3 EDN1 EDN1 CACNA1D CACNA1D MYLK2 MYLK2 PTGIR PTGIR PTRHD1 PTRHD1 GNA12 GNA12 NPPB NPPB EDNRA EDNRA PLA2G2E PLA2G2E GNAS GNAS ADRA1D ADRA1D CALCA CALCA EDN3 EDN3 PLA2G4A PLA2G4A KCNMA1 KCNMA1 ADRA1B ADRA1B RAF1 RAF1 MYLK3 MYLK3 ADRA1A ADRA1A PRKACA PRKACA MYL6 MYL6 ADCY9 ADCY9 PRKG1 PRKG1 CALCRL CALCRL EFCAB13 EFCAB13 LOC105515734 LOC105515734 PLA2G4E PLA2G4E KCNMB1 KCNMB1 CACNA1F CACNA1F ROCK1 ROCK1 MAPK3 MAPK3 ARHGEF1 ARHGEF1 ENSCANP00000014997 ENSCANP00000014997 KCNMB3 KCNMB3 CALM3 CALM3 PLA2G3 PLA2G3 ADORA2A ADORA2A CALML6 CALML6 CALCB CALCB NPR2 NPR2 NPR1 NPR1 AGT AGT PPP1CB PPP1CB MAP2K2 MAP2K2 GUCY1A2 GUCY1A2 KCNMB2 KCNMB2 KCNU1 KCNU1 CACNA1S CACNA1S AVPR1A AVPR1A MRVI1 MRVI1 PLA2G2F PLA2G2F PRKCG PRKCG ADCY2 ADCY2 ENSCANP00000009565 ENSCANP00000009565 MYLK4 MYLK4 ENSCANP00000009406 ENSCANP00000009406 ERF ERF RHOC RHOC MYH14 MYH14 PRKCQ PRKCQ PLA2G12A PLA2G12A RHOA RHOA PLA2G2D PLA2G2D PRKACB PRKACB MYH9 MYH9 PPP1R12C PPP1R12C GNAQ GNAQ ARHGEF11 ARHGEF11 CALD1 CALD1 ADORA2B ADORA2B ERFL ERFL PRKCD PRKCD CALML3 CALML3 PLA2G4D PLA2G4D ENSCANP00000003071 ENSCANP00000003071 CALM1 CALM1 MYH10 MYH10 PLCB2 PLCB2 PRKCA PRKCA LOC105500726 LOC105500726 ARAF ARAF PRKCB PRKCB JMJD7 JMJD7 PLA2G5 PLA2G5 ITPR3 ITPR3 ADCY5 ADCY5 ETV3L ETV3L PPP1CC PPP1CC MYH11 MYH11 EDN2 EDN2 CALM2 CALM2 ADM ADM ESYT1 ESYT1 PLA2G2A PLA2G2A KCNMB4 KCNMB4 LYVE1 LYVE1 ADCY3 ADCY3 MAPK1 MAPK1 NPPA NPPA ADCY8 ADCY8 PRKCH PRKCH CALML4 CALML4 RAMP1 RAMP1 ENSCANP00000028447 ENSCANP00000028447 ITPR1 ITPR1 PPP1R12A PPP1R12A ADCY4 ADCY4 CYP4B1 CYP4B1 ADCY7 ADCY7 ADCY6 ADCY6 PPP1R14A PPP1R14A LOC105506399 LOC105506399 PRKCE PRKCE PLA2G4F PLA2G4F ROCK2 ROCK2 CACNA1C CACNA1C NPPC NPPC AVPR1B AVPR1B RAMP2 RAMP2 PVALEF PVALEF PLCB4 PLCB4 LOC105515267 LOC105515267 PLA2G4B PLA2G4B PLA2G6 PLA2G6 MAP2K1 MAP2K1 PPP1R12B PPP1R12B EFCAB3 EFCAB3 BRAF BRAF PLA2G4C PLA2G4C GUCY1A1 GUCY1A1 AGTR1 AGTR1 PLCB1 PLCB1 GNA13 GNA13 ITPR2 ITPR2 ADCY1 ADCY1 ETV3 ETV3 PLA2G2C PLA2G2C ESYT2 ESYT2 ENSCANP00000038818 ENSCANP00000038818 ARHGEF12 ARHGEF12 MYLK MYLK PLA2G12B PLA2G12B LOC105510524 LOC105510524 ACTG2 ACTG2 ENSCANP00000039354 ENSCANP00000039354 PLCB3 PLCB3 ESYT3 ESYT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYL9Myosin light chain 9. (172 aa)
PROCA1Protein interacting with cyclin A1. (362 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (642 aa)
PLA2G1BPhospholipase A(2). (147 aa)
ENSCANP00000001976Uncharacterized protein. (112 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
RAMP3Receptor activity modifying protein 3. (151 aa)
EDN1Endothelin 1. (211 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
PTGIRProstaglandin I2 receptor. (386 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
GNA12G protein subunit alpha 12. (310 aa)
NPPBNatriuretic peptide B. (134 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PLA2G2EPhospholipase A(2). (142 aa)
GNASGNAS complex locus. (913 aa)
ADRA1DAdrenoceptor alpha 1D. (484 aa)
CALCACalcitonin related polypeptide alpha. (142 aa)
EDN3Endothelin 3. (230 aa)
PLA2G4APhospholipase A2. (749 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1280 aa)
ADRA1BAdrenoceptor alpha 1B. (372 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
MYLK3Myosin light chain kinase 3. (819 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (345 aa)
MYL6Uncharacterized protein. (226 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (461 aa)
EFCAB13EF-hand calcium binding domain 13. (973 aa)
LOC105515734Uncharacterized protein. (156 aa)
PLA2G4EPhospholipase A2. (869 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1971 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (965 aa)
ENSCANP00000014997Uncharacterized protein. (124 aa)
KCNMB3Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (250 aa)
CALM3Calmodulin 3. (149 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
CALML6Calmodulin like 6. (181 aa)
CALCBCalcitonin related polypeptide beta. (138 aa)
NPR2Guanylate cyclase. (1047 aa)
NPR1Guanylate cyclase. (958 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (369 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (691 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1124 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
MRVI1Murine retrovirus integration site 1 homolog. (911 aa)
PLA2G2FPhospholipase A(2). (199 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1014 aa)
ENSCANP00000009565Uncharacterized protein. (651 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (389 aa)
ENSCANP00000009406Uncharacterized protein; Belongs to the calmodulin family. (163 aa)
ERFETS2 repressor factor. (538 aa)
RHOCRas homolog family member C. (193 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1965 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
PLA2G12APhospholipase A2 group XIIA. (187 aa)
RHOARas homolog family member A. (193 aa)
PLA2G2DPhospholipase A(2). (145 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
PPP1R12CProtein phosphatase 1 regulatory subunit 12C. (653 aa)
GNAQG protein subunit alpha q. (313 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1561 aa)
CALD1Caldesmon 1. (793 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa)
ERFLETS repressor factor like. (354 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
PLA2G4DPhospholipase A2. (794 aa)
ENSCANP00000003071SER_THR_PHOSPHATASE domain-containing protein. (146 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1977 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
LOC105500726Uncharacterized protein. (192 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (587 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
JMJD7Jumonji domain containing 7. (316 aa)
PLA2G5Phospholipase A(2). (138 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1121 aa)
ETV3LETS variant 3 like. (358 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1670 aa)
EDN2Endothelin 2. (178 aa)
CALM2Calmodulin 2. (149 aa)
ADMAdrenomedullin. (185 aa)
ESYT1Extended synaptotagmin 1. (1110 aa)
PLA2G2APhospholipase A(2). (144 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
LYVE1Lymphatic vessel endothelial hyaluronan receptor 1. (321 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1142 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
NPPANatriuretic peptide A. (153 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
CALML4Calmodulin like 4. (192 aa)
RAMP1Receptor activity modifying protein 1. (148 aa)
ENSCANP00000028447Uncharacterized protein; Belongs to the calmodulin family. (173 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2697 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1030 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
CYP4B1Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. (511 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1083 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
PPP1R14AProtein phosphatase 1 regulatory inhibitor subunit 14A. (121 aa)
LOC105506399Uncharacterized protein. (246 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
PLA2G4FPhospholipase A2. (791 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2134 aa)
NPPCNatriuretic peptide C. (126 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (424 aa)
RAMP2Receptor activity modifying protein 2. (216 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
LOC105515267Uncharacterized protein. (519 aa)
PLA2G4BPhospholipase A2. (781 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (1046 aa)
EFCAB3EF-hand calcium binding domain 3. (488 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (747 aa)
PLA2G4CPhospholipase A2 group IVC. (551 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa)
GNA13G protein subunit alpha 13. (282 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (976 aa)
ETV3ETS variant 3. (511 aa)
PLA2G2CPhospholipase A(2). (150 aa)
ESYT2Extended synaptotagmin 2. (907 aa)
ENSCANP00000038818Uncharacterized protein. (145 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1471 aa)
MYLKMyosin light chain kinase. (1914 aa)
PLA2G12BPhospholipase A2 group XIIB. (195 aa)
LOC105510524Uncharacterized protein. (153 aa)
ACTG2Actin gamma 2, smooth muscle. (376 aa)
ENSCANP00000039354Protein kinase domain-containing protein. (353 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa)
ESYT3Extended synaptotagmin 3. (880 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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