STRINGSTRING
PLA2G4B PLA2G4B PIK3R3 PIK3R3 PLA2G4C PLA2G4C PIK3CD PIK3CD PTK2 PTK2 LPXN LPXN PPP1R14B PPP1R14B CDC42 CDC42 ENSCANP00000039354 ENSCANP00000039354 PPP3CC PPP3CC MAPK14 MAPK14 SRC SRC MAPK11 MAPK11 PLCG2 PLCG2 PRKCA PRKCA PLA2G4D PLA2G4D ENSCANP00000004265 ENSCANP00000004265 BAD BAD ENSCANP00000005072 ENSCANP00000005072 HRAS HRAS KRAS KRAS PPP3CB PPP3CB NFATC2 NFATC2 CASP9 CASP9 PRKCG PRKCG PXN PXN ENSCANP00000011118 ENSCANP00000011118 PLCG1 PLCG1 GEM GEM MAP2K2 MAP2K2 ENSCANP00000013076 ENSCANP00000013076 MAPK12 MAPK12 LOC105521593 LOC105521593 AKT1 AKT1 NOS3 NOS3 RAC2 RAC2 LOC105504658 LOC105504658 MAPK3 MAPK3 PLA2G4E PLA2G4E PIK3CA PIK3CA SPHK2 SPHK2 RAF1 RAF1 PPP3R1 PPP3R1 PLA2G4A PLA2G4A PTGS2 PTGS2 ENSCANP00000019829 ENSCANP00000019829 PPP3R2 PPP3R2 RRAD RRAD LOC105514986 LOC105514986 ENSCANP00000020790 ENSCANP00000020790 PIK3R1 PIK3R1 AKT2 AKT2 PRKCB PRKCB JMJD7 JMJD7 CSDE1 CSDE1 SPHK1 SPHK1 SHC2 SHC2 SH2D2A SH2D2A MAPKAPK3 MAPKAPK3 TGFB1I1 TGFB1I1 MAPK1 MAPK1 AKT3 AKT3 PPP3CA PPP3CA VEGFA VEGFA SH2D7 SH2D7 PIK3CB PIK3CB LOC105514391 LOC105514391 LRRC45 LRRC45 PLA2G4F PLA2G4F PIK3R2 PIK3R2 KDR KDR MAPK13 MAPK13 MAPKAPK2 MAPKAPK2 MAP2K1 MAP2K1 REM1 REM1 RAC1 RAC1 ERAS ERAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLA2G4BPhospholipase A2. (781 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
PLA2G4CPhospholipase A2 group IVC. (551 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1071 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (132 aa)
CDC42Cell division cycle 42. (191 aa)
ENSCANP00000039354Protein kinase domain-containing protein. (353 aa)
PPP3CCSerine/threonine-protein phosphatase. (499 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SRCTyrosine-protein kinase. (458 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1257 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
PLA2G4DPhospholipase A2. (794 aa)
ENSCANP00000004265Uncharacterized protein. (37 aa)
BADBCL2 associated agonist of cell death. (167 aa)
ENSCANP00000005072Uncharacterized protein. (168 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
NFATC2Nuclear factor of activated T cells 2. (923 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (416 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
PXNPaxillin. (1076 aa)
ENSCANP00000011118Uncharacterized protein. (176 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (369 aa)
ENSCANP00000013076Uncharacterized protein. (164 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
LOC105521593Uncharacterized protein. (181 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
RAC2Rac family small GTPase 2. (192 aa)
LOC105504658Uncharacterized protein. (571 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PLA2G4EPhospholipase A2. (869 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SPHK2Sphingosine kinase 2. (658 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
PPP3R1Uncharacterized protein. (189 aa)
PLA2G4APhospholipase A2. (749 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ENSCANP00000019829Uncharacterized protein. (98 aa)
PPP3R2Protein phosphatase 3 regulatory subunit B, beta. (174 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
LOC105514986SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (182 aa)
ENSCANP00000020790Uncharacterized protein. (84 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
JMJD7Jumonji domain containing 7. (316 aa)
CSDE1Uncharacterized protein. (844 aa)
SPHK1Sphingosine kinase 1. (448 aa)
SHC2SHC adaptor protein 2. (381 aa)
SH2D2ASH2 domain containing 2A. (399 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (412 aa)
SH2D7SH2 domain containing 7. (456 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
LOC105514391Uncharacterized protein. (190 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
PLA2G4FPhospholipase A2. (791 aa)
PIK3R2Uncharacterized protein. (601 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
MAPK13Mitogen-activated protein kinase. (491 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (431 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
RAC1Uncharacterized protein. (205 aa)
ERASES cell expressed Ras. (233 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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