STRINGSTRING
ENSCANP00000010884 ENSCANP00000010884 BIRC5 BIRC5 FZD3 FZD3 PPP2R1B PPP2R1B ENSCANP00000035277 ENSCANP00000035277 WNT16 WNT16 DLG1 DLG1 CTNNA1 CTNNA1 TCF7L1 TCF7L1 WNT2B WNT2B ACTG1 ACTG1 WNT5A WNT5A PPP2R2D PPP2R2D ENSCANP00000032589 ENSCANP00000032589 BMPR2 BMPR2 MOB1A MOB1A TGFB3 TGFB3 FBXW11 FBXW11 FRMD6 FRMD6 PPP2R2C PPP2R2C BMP8B BMP8B ID2 ID2 ENSCANP00000031005 ENSCANP00000031005 ENSCANP00000030373 ENSCANP00000030373 PPP2R1A PPP2R1A MYC MYC WWTR1 WWTR1 TGFBR1 TGFBR1 SERPINE1 SERPINE1 PPP2CA PPP2CA YWHAG YWHAG SMAD4 SMAD4 CSNK1D CSNK1D FZD7 FZD7 FZD5 FZD5 ENSCANP00000028682 ENSCANP00000028682 LOC105512042 LOC105512042 WNT9A WNT9A DVL2 DVL2 NKD1 NKD1 WNT3A WNT3A DLG4 DLG4 FZD8 FZD8 CCND2 CCND2 PPP2CB PPP2CB LIMD1 LIMD1 TCF7 TCF7 FZD2 FZD2 WNT4 WNT4 DLG2 DLG2 CRB1 CRB1 NKD2 NKD2 LOC105521231 LOC105521231 BIRC3 BIRC3 ACTL8 ACTL8 GDF5 GDF5 PPP1CC PPP1CC LOC105527362 LOC105527362 TEAD3 TEAD3 BMP7 BMP7 CCN2 CCN2 AXIN1 AXIN1 WWC1 WWC1 CDH1 CDH1 ENSCANP00000022034 ENSCANP00000022034 WNT6 WNT6 TGFB2 TGFB2 LOC105527785 LOC105527785 CCND1 CCND1 LOC105524240 LOC105524240 APC2 APC2 WNT7A WNT7A FZD6 FZD6 ENSCANP00000018854 ENSCANP00000018854 ENSCANP00000018773 ENSCANP00000018773 WNT8B WNT8B DLG3 DLG3 SMAD1 SMAD1 WNT2 WNT2 ENSCANP00000017605 ENSCANP00000017605 TCF7L2 TCF7L2 MYO15A MYO15A PRKCI PRKCI LDAH LDAH ENSCANP00000015995 ENSCANP00000015995 YAP1 YAP1 ITGB2 ITGB2 RASSF6 RASSF6 WNT5B WNT5B ENSCANP00000014845 ENSCANP00000014845 ENSCANP00000014581 ENSCANP00000014581 WNT8A WNT8A WNT10B WNT10B GDF6 GDF6 TP73 TP73 BMP4 BMP4 YWHAH YWHAH GDF7 GDF7 ENSCANP00000013595 ENSCANP00000013595 BMPR1A BMPR1A PPP2R2B PPP2R2B PPP1CB PPP1CB ENSCANP00000013074 ENSCANP00000013074 BMP2 BMP2 SNAI2 SNAI2 AFP AFP YWHAE YWHAE PRKCZ PRKCZ ENSCANP00000011903 ENSCANP00000011903 WNT11 WNT11 PARD3 PARD3 CTNNB1 CTNNB1 PPP2R2A PPP2R2A TEAD4 TEAD4 BTRC BTRC GSK3B GSK3B CCND3 CCND3 WNT3 WNT3 RASSF1 RASSF1 TP53BP2 TP53BP2 LOC105510963 LOC105510963 WNT1 WNT1 BMP6 BMP6 FZD4 FZD4 TGFB1 TGFB1 ENSCANP00000008647 ENSCANP00000008647 YWHAB YWHAB BMPR1B BMPR1B YWHAQ YWHAQ BMP5 BMP5 LLGL2 LLGL2 CTNNA2 CTNNA2 LLGL1 LLGL1 LATS2 LATS2 APC APC SAV1 SAV1 PARD6G PARD6G SMAD7 SMAD7 STK3 STK3 SOX2 SOX2 LOC105521177 LOC105521177 LATS1 LATS1 NF2 NF2 PATJ PATJ MOB1B MOB1B WNT7B WNT7B TGFBR2 TGFBR2 BIRC2 BIRC2 DVL1 DVL1 DLG5 DLG5 PARD6A PARD6A ENSCANP00000003071 ENSCANP00000003071 FGF1 FGF1 PPP1CA PPP1CA WNT9B WNT9B LOC105502368 LOC105502368 MYO15B MYO15B ACTL7A ACTL7A WNT10A WNT10A SCRIB SCRIB MPP5 MPP5 AXIN2 AXIN2 ACTL7B ACTL7B SMAD3 SMAD3 LEF1 LEF1 LRRC1 LRRC1 ENSCANP00000040247 ENSCANP00000040247 TEAD2 TEAD2 YWHAZ YWHAZ DVL3 DVL3 AREG AREG GLI2 GLI2 POTEE POTEE FRMD1 FRMD1 CRB2 CRB2 TEAD1 TEAD1 ID1 ID1 AMOT AMOT SMAD2 SMAD2 AJUBA AJUBA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCANP00000010884Uncharacterized protein. (338 aa)
BIRC5Baculoviral IAP repeat containing 5. (147 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
ENSCANP0000003527714_3_3 domain-containing protein; Belongs to the 14-3-3 family. (235 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)
CTNNA1Catenin alpha 1. (906 aa)
TCF7L1Transcription factor 7 like 1. (512 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
ACTG1Uncharacterized protein. (376 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (446 aa)
ENSCANP0000003258914_3_3 domain-containing protein; Belongs to the 14-3-3 family. (251 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
MOB1AMOB kinase activator 1A. (216 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
FBXW11F-box and WD repeat domain containing 11. (542 aa)
FRMD6FERM domain containing 6. (622 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
BMP8BTGF_BETA_2 domain-containing protein. (336 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
ENSCANP00000031005Uncharacterized protein. (101 aa)
ENSCANP0000003037314_3_3 domain-containing protein; Belongs to the 14-3-3 family. (226 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (594 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (337 aa)
PPP2CASerine/threonine-protein phosphatase. (275 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CSNK1DCasein kinase 1 delta; Belongs to the protein kinase superfamily. (427 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
ENSCANP0000002868214_3_3 domain-containing protein; Belongs to the 14-3-3 family. (198 aa)
LOC105512042ANK_REP_REGION domain-containing protein; Belongs to the actin family. (796 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (564 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (733 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (488 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
PPP2CBSerine/threonine-protein phosphatase. (275 aa)
LIMD1LIM domains containing 1. (677 aa)
TCF7Transcription factor 7. (398 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (543 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
DLG2Discs large MAGUK scaffold protein 2. (975 aa)
CRB1Crumbs cell polarity complex component 1. (1376 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (380 aa)
LOC105521231Uncharacterized protein; Belongs to the actin family. (376 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
GDF5Growth differentiation factor 5. (499 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
LOC105527362Uncharacterized protein. (835 aa)
TEAD3Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (435 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
CCN2Cellular communication network factor 2. (301 aa)
AXIN1Axin 1. (859 aa)
WWC1WW and C2 domain containing 1. (1119 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (770 aa)
ENSCANP0000002203414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (214 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LOC105527785Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
LOC105524240Uncharacterized protein. (370 aa)
APC2APC regulator of WNT signaling pathway 2. (1681 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
ENSCANP00000018854Uncharacterized protein; Belongs to the actin family. (349 aa)
ENSCANP00000018773PDZ domain-containing protein. (299 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (863 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
ENSCANP00000017605Uncharacterized protein; Belongs to the actin family. (163 aa)
TCF7L2Transcription factor 7 like 2. (577 aa)
MYO15AMyosin XVA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3268 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
LDAHLipid droplet associated hydrolase. (324 aa)
ENSCANP00000015995Uncharacterized protein. (157 aa)
YAP1Yes associated protein 1. (479 aa)
ITGB2Integrin beta. (769 aa)
RASSF6Ras association domain family member 6. (337 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
ENSCANP00000014845Uncharacterized protein. (168 aa)
ENSCANP0000001458114_3_3 domain-containing protein. (97 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
GDF6Growth differentiation factor 6. (455 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (224 aa)
GDF7Growth differentiation factor 7. (366 aa)
ENSCANP0000001359514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (124 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
ENSCANP00000013074Uncharacterized protein; Belongs to the actin family. (156 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
AFPAlpha fetoprotein. (635 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (392 aa)
ENSCANP0000001190314_3_3 domain-containing protein. (107 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
PARD3Par-3 family cell polarity regulator. (1316 aa)
CTNNB1Catenin beta 1. (781 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
TEAD4Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (434 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (527 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (242 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
RASSF1Ras association domain family member 1. (270 aa)
TP53BP2Tumor protein p53 binding protein 2. (1102 aa)
LOC105510963Serine/threonine-protein phosphatase. (291 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
BMP6Bone morphogenetic protein 6. (331 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
ENSCANP00000008647Uncharacterized protein; Belongs to the actin family. (146 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
LLGL2LLGL scribble cell polarity complex component 2. (1020 aa)
CTNNA2Catenin alpha 2. (953 aa)
LLGL1LLGL scribble cell polarity complex component 1. (1052 aa)
LATS2Non-specific serine/threonine protein kinase. (984 aa)
APCAPC regulator of WNT signaling pathway. (2843 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
PARD6GPar-6 family cell polarity regulator gamma. (352 aa)
SMAD7Mothers against decapentaplegic homolog. (431 aa)
STK3Serine/threonine kinase 3. (489 aa)
SOX2SRY-box transcription factor 2. (302 aa)
LOC105521177TGF_BETA_2 domain-containing protein. (238 aa)
LATS1Large tumor suppressor kinase 1. (1130 aa)
NF2Neurofibromin 2. (561 aa)
PATJPATJ crumbs cell polarity complex component. (1778 aa)
MOB1BMOB kinase activator 1B. (221 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
DVL1Dishevelled segment polarity protein 1. (694 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1896 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
ENSCANP00000003071SER_THR_PHOSPHATASE domain-containing protein. (146 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
LOC105502368Uncharacterized protein. (372 aa)
MYO15BMyosin XVB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2966 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
SCRIBScribble planar cell polarity protein. (1662 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
AXIN2Axin 2. (843 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
ENSCANP0000004024714_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa)
TEAD2TEA domain transcription factor 2. (377 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (253 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
AREGAmphiregulin. (275 aa)
GLI2GLI family zinc finger 2. (1585 aa)
POTEEANK_REP_REGION domain-containing protein; Belongs to the actin family. (952 aa)
FRMD1FERM domain containing 1. (505 aa)
CRB2Crumbs cell polarity complex component 2. (1287 aa)
TEAD1TEA domain transcription factor 1. (434 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
AMOTAngiomotin. (1084 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
AJUBAAjuba LIM protein. (538 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
Server load: low (26%) [HD]