STRINGSTRING
MEIS2 MEIS2 ISL1 ISL1 DVL3 DVL3 ENSCANP00000039354 ENSCANP00000039354 MAPK14 MAPK14 SMAD2 SMAD2 FGFR1 FGFR1 PIK3CD PIK3CD FZD3 FZD3 ONECUT2 ONECUT2 ESX1 ESX1 TCF3 TCF3 PIK3R3 PIK3R3 WNT16 WNT16 HOXB1 HOXB1 MAP2K1 MAP2K1 REST REST NODAL NODAL JAK2 JAK2 FGF2 FGF2 FGFR3 FGFR3 LOC105516700 LOC105516700 WNT2B WNT2B HESX1 HESX1 MAPK13 MAPK13 WNT5A WNT5A PIK3R2 PIK3R2 DUSP9 DUSP9 BMPR2 BMPR2 ISL2 ISL2 MEIS1 MEIS1 ID2 ID2 INHBE INHBE PIK3CB PIK3CB JARID2 JARID2 MYC MYC NFIL3 NFIL3 SMAD4 SMAD4 NEUROG1 NEUROG1 FZD7 FZD7 FZD5 FZD5 WNT9A WNT9A DVL2 DVL2 WNT3A WNT3A AKT3 AKT3 PAX6 PAX6 ESRRB ESRRB FZD8 FZD8 LOC105516701 LOC105516701 TCF7 TCF7 ACVR2B ACVR2B FZD2 FZD2 WNT4 WNT4 MAPK1 MAPK1 ZIC2 ZIC2 HAND1 HAND1 SETDB1 SETDB1 LHX5 LHX5 PCGF1 PCGF1 CSDE1 CSDE1 ACVR1B ACVR1B AXIN1 AXIN1 ZIC1 ZIC1 STAT3 STAT3 FGFR4 FGFR4 AKT2 AKT2 PIK3R1 PIK3R1 ZFHX3 ZFHX3 LIFR LIFR WNT6 WNT6 DLX5 DLX5 IGF1 IGF1 ENSCANP00000019829 ENSCANP00000019829 APC2 APC2 WNT7A WNT7A FZD6 FZD6 FGFR2 FGFR2 WNT8B WNT8B PCGF5 PCGF5 ID3 ID3 RAF1 RAF1 SMAD1 SMAD1 WNT2 WNT2 NANOG NANOG PIK3CA PIK3CA SMAD5 SMAD5 JAK1 JAK1 IL6ST IL6ST MAPK3 MAPK3 LOC105504658 LOC105504658 WNT5B WNT5B KAT6A KAT6A HOXD1 HOXD1 AKT1 AKT1 TBX3 TBX3 ENSCANP00000014526 ENSCANP00000014526 WNT8A WNT8A WNT10B WNT10B BMP4 BMP4 MAPK12 MAPK12 ONECUT1 ONECUT1 BMPR1A BMPR1A PRRX1 PRRX1 PCGF6 PCGF6 IGF1R IGF1R ACVR1 ACVR1 MAP2K2 MAP2K2 OTX1 OTX1 HOXA1 HOXA1 WNT11 WNT11 CTNNB1 CTNNB1 RIF1 RIF1 GSK3B GSK3B WNT3 WNT3 SMAD9 SMAD9 SKIL SKIL WNT1 WNT1 FZD4 FZD4 ACVR1C ACVR1C ENSCANP00000008410 ENSCANP00000008410 BMPR1B BMPR1B APC APC KLF4 KLF4 LHX1 LHX1 KRAS KRAS LOC105527518 LOC105527518 ACVR2A ACVR2A SOX2 SOX2 HRAS HRAS ZIC3 ZIC3 INHBA INHBA TBX2 TBX2 WNT7B WNT7B DVL1 DVL1 ESRRG ESRRG MYF5 MYF5 LIF LIF WNT9B WNT9B MAPK11 MAPK11 ERAS ERAS WNT10A WNT10A SMARCAD1 SMARCAD1 AXIN2 AXIN2 GRB2 GRB2 INHBC INHBC POU5F1 POU5F1 JAK3 JAK3 PCGF2 PCGF2 SMAD3 SMAD3 LOC105523222 LOC105523222 PCGF3 PCGF3 ID1 ID1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MEIS2Meis homeobox 2. (477 aa)
ISL1ISL LIM homeobox 1. (349 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
ENSCANP00000039354Protein kinase domain-containing protein. (353 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
FGFR1Fibroblast growth factor receptor. (815 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1071 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
ONECUT2One cut domain family member. (418 aa)
ESX1Homeobox domain-containing protein. (359 aa)
TCF3Transcription factor 3. (658 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
HOXB1Homeobox B1. (304 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
RESTRE1 silencing transcription factor. (1096 aa)
NODALNodal growth differentiation factor. (347 aa)
JAK2Tyrosine-protein kinase. (1139 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
FGFR3Fibroblast growth factor receptor. (808 aa)
LOC105516700TGF_BETA_2 domain-containing protein. (311 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
HESX1HESX homeobox 1. (185 aa)
MAPK13Mitogen-activated protein kinase. (491 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PIK3R2Uncharacterized protein. (601 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (385 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
ISL2ISL LIM homeobox 2. (359 aa)
MEIS1Meis homeobox 1. (463 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
INHBEInhibin subunit beta E. (351 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1246 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
NFIL3Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T- cells. Competes for the same consensus-binding site with PAR DNA- bi [...] (462 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
NEUROG1Neurogenin 1. (237 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PAX6Paired box 6. (478 aa)
ESRRBEstrogen related receptor beta. (372 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (488 aa)
LOC105516701TGF_BETA_2 domain-containing protein. (283 aa)
TCF7Transcription factor 7. (398 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (750 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (543 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
ZIC2Zic family member 2. (374 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
SETDB1SET domain bifurcated histone lysine methyltransferase 1. (1170 aa)
LHX5LIM homeobox 5. (353 aa)
PCGF1Polycomb group ring finger 1. (259 aa)
CSDE1Uncharacterized protein. (844 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
AXIN1Axin 1. (859 aa)
ZIC1Zic family member 1. (373 aa)
STAT3Signal transducer and activator of transcription. (795 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ZFHX3Zinc finger homeobox 3. (3690 aa)
LIFRLIF receptor subunit alpha. (1097 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
DLX5Distal-less homeobox 5. (289 aa)
IGF1Insulin like growth factor 1. (208 aa)
ENSCANP00000019829Uncharacterized protein. (98 aa)
APC2APC regulator of WNT signaling pathway 2. (1681 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
FGFR2Fibroblast growth factor receptor. (838 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
PCGF5Polycomb group ring finger 5. (256 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
NANOGHomeobox domain-containing protein. (305 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
IL6STInterleukin 6 signal transducer. (860 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
LOC105504658Uncharacterized protein. (571 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2003 aa)
HOXD1Homeobox D1. (248 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
TBX3T-box transcription factor 3. (743 aa)
ENSCANP00000014526Homeobox domain-containing protein. (275 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
ONECUT1One cut domain family member. (465 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
PRRX1Paired related homeobox 1. (245 aa)
PCGF6Polycomb group ring finger 6. (288 aa)
IGF1RTyrosine-protein kinase receptor. (1335 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (369 aa)
OTX1Orthodenticle homeobox 1. (288 aa)
HOXA1Homeobox A1. (335 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
CTNNB1Catenin beta 1. (781 aa)
RIF1Replication timing regulatory factor 1. (2459 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
SKILSKI like proto-oncogene. (684 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (489 aa)
ENSCANP00000008410Uncharacterized protein. (260 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
APCAPC regulator of WNT signaling pathway. (2843 aa)
KLF4Kruppel like factor 4. (479 aa)
LHX1LIM homeobox 1. (406 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
LOC105527518RING-type domain-containing protein. (326 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
SOX2SRY-box transcription factor 2. (302 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ZIC3Zic family member 3. (466 aa)
INHBAInhibin subunit beta A. (426 aa)
TBX2T-box transcription factor 2. (590 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
DVL1Dishevelled segment polarity protein 1. (694 aa)
ESRRGEstrogen related receptor gamma. (470 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
LIFLIF interleukin 6 family cytokine. (204 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
ERASES cell expressed Ras. (233 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
SMARCAD1Uncharacterized protein. (1026 aa)
AXIN2Axin 2. (843 aa)
GRB2Uncharacterized protein. (156 aa)
INHBCInhibin subunit beta C. (352 aa)
POU5F1POU domain protein. (360 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
LOC105523222Homeobox domain-containing protein. (278 aa)
PCGF3Polycomb group ring finger 3. (242 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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