STRINGSTRING
SYK SYK F2 F2 PIK3R2 PIK3R2 ROCK2 ROCK2 PLA2G4F PLA2G4F LOC105506399 LOC105506399 ADCY6 ADCY6 RASGRP1 RASGRP1 ADCY7 ADCY7 ENSCANP00000030491 ENSCANP00000030491 ADCY4 ADCY4 SNAP23 SNAP23 PIK3CB PIK3CB PPP1R12A PPP1R12A ITPR1 ITPR1 BTK BTK SSPO SSPO LOC105512042 LOC105512042 AKT3 AKT3 ADCY8 ADCY8 MAPK1 MAPK1 ADCY3 ADCY3 LRRC15 LRRC15 LOC105521231 LOC105521231 RAP1A RAP1A ACTL8 ACTL8 TLN1 TLN1 PPP1CC PPP1CC DHRSX DHRSX ITGB3 ITGB3 TLN2 TLN2 LCP2 LCP2 ZNF408 ZNF408 ADCY5 ADCY5 ITPR3 ITPR3 COL1A1 COL1A1 GNAI1 GNAI1 JMJD7 JMJD7 FGB FGB PTRHD1 PTRHD1 AKT2 AKT2 PIK3R1 PIK3R1 ENSCANP00000021474 ENSCANP00000021474 GP1BA GP1BA GNAS GNAS COL3A1 COL3A1 LOC105524240 LOC105524240 SRMS SRMS PLA2G4A PLA2G4A ENSCANP00000018854 ENSCANP00000018854 MYLK3 MYLK3 PRKACA PRKACA STIM1 STIM1 FYN FYN ENSCANP00000017605 ENSCANP00000017605 LOC105514341 LOC105514341 ADCY9 ADCY9 PRKG1 PRKG1 PRKCI PRKCI PIK3CA PIK3CA PLA2G4E PLA2G4E PIK3R5 PIK3R5 ROCK1 ROCK1 MAPK3 MAPK3 ARHGEF1 ARHGEF1 ENSCANP00000014775 ENSCANP00000014775 NOS3 NOS3 AKT1 AKT1 MAPK12 MAPK12 PTGS1 PTGS1 PPP1CB PPP1CB ENSCANP00000013074 ENSCANP00000013074 ITGB1 ITGB1 GUCY1A2 GUCY1A2 GNAI2 GNAI2 GNAI3 GNAI3 ARHGAP35 ARHGAP35 PRKCZ PRKCZ FCER1G FCER1G COL1A2 COL1A2 P2RX1 P2RX1 ADCY2 ADCY2 VWF VWF MYLK4 MYLK4 RHOC RHOC ENSCANP00000008647 ENSCANP00000008647 RHOA RHOA PRKACB PRKACB GP6 GP6 TBXA2R TBXA2R FGA FGA GNAQ GNAQ FERMT3 FERMT3 RDH13 RDH13 GP1BB GP1BB VASP VASP PLA2G4D PLA2G4D P2RY12 P2RY12 ENSCANP00000003071 ENSCANP00000003071 PLCB2 PLCB2 GUCY1B1 GUCY1B1 P2RY1 P2RY1 PLCG2 PLCG2 PTGIR PTGIR PPP1CA PPP1CA MYL12A MYL12A MAPK11 MAPK11 PIK3CG PIK3CG ACTL7A ACTL7A PIK3R6 PIK3R6 GP9 GP9 ACTL7B ACTL7B MYLK2 MYLK2 VAMP8 VAMP8 ITGA2B ITGA2B MYLK MYLK ARHGEF12 ARHGEF12 POTEE POTEE MYL12B MYL12B RDH14 RDH14 ITGA2 ITGA2 ADCY1 ADCY1 ITPR2 ITPR2 TBXAS1 TBXAS1 PRKG2 PRKG2 FCGR2A FCGR2A PIK3CD PIK3CD GNA13 GNA13 PLCB1 PLCB1 GUCY1A1 GUCY1A1 PLA2G4C PLA2G4C FGG FGG F2RL3 F2RL3 PTK6 PTK6 PIK3R3 PIK3R3 F2R F2R PLA2G4B PLA2G4B LYN LYN RAP1B RAP1B ORAI1 ORAI1 SRC SRC PLCB3 PLCB3 MAPK14 MAPK14 RASGRP2 RASGRP2 PLCB4 PLCB4 ACTG1 ACTG1 MAPK13 MAPK13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYKTyrosine-protein kinase. (635 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (624 aa)
PIK3R2Uncharacterized protein. (601 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa)
PLA2G4FPhospholipase A2. (791 aa)
LOC105506399Uncharacterized protein. (246 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
RASGRP1RAS guanyl releasing protein 1. (793 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1083 aa)
ENSCANP00000030491WH1 domain-containing protein. (137 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
SNAP23Synaptosome associated protein 23. (211 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1030 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2697 aa)
BTKTyrosine-protein kinase. (692 aa)
SSPOSCO-spondin. (5142 aa)
LOC105512042ANK_REP_REGION domain-containing protein; Belongs to the actin family. (796 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1142 aa)
LRRC15Leucine rich repeat containing 15. (584 aa)
LOC105521231Uncharacterized protein; Belongs to the actin family. (376 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
TLN1Talin 1. (2559 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
DHRSXDehydrogenase/reductase X-linked; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (293 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
TLN2Talin 2. (2544 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
ZNF408Zinc finger protein 408. (719 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1121 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
GNAI1G protein subunit alpha i1. (354 aa)
JMJD7Jumonji domain containing 7. (316 aa)
FGBFibrinogen beta chain. (491 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSCANP00000021474Uncharacterized protein. (136 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (650 aa)
GNASGNAS complex locus. (913 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
LOC105524240Uncharacterized protein. (370 aa)
SRMSTyrosine-protein kinase. (492 aa)
PLA2G4APhospholipase A2. (749 aa)
ENSCANP00000018854Uncharacterized protein; Belongs to the actin family. (349 aa)
MYLK3Myosin light chain kinase 3. (819 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (345 aa)
STIM1Stromal interaction molecule 1. (791 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSCANP00000017605Uncharacterized protein; Belongs to the actin family. (163 aa)
LOC105514341Uncharacterized protein. (220 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PLA2G4EPhospholipase A2. (869 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (879 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (965 aa)
ENSCANP00000014775Uncharacterized protein. (130 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (599 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
ENSCANP00000013074Uncharacterized protein; Belongs to the actin family. (156 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (691 aa)
GNAI2G protein subunit alpha i2. (355 aa)
GNAI3G protein subunit alpha i3. (301 aa)
ARHGAP35Rho GTPase activating protein 35. (1509 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (392 aa)
FCER1GFc fragment of IgE receptor Ig. (112 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (375 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1014 aa)
VWFVon Willebrand factor. (2758 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (389 aa)
RHOCRas homolog family member C. (193 aa)
ENSCANP00000008647Uncharacterized protein; Belongs to the actin family. (146 aa)
RHOARas homolog family member A. (193 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GP6Uncharacterized protein. (318 aa)
TBXA2RThromboxane A2 receptor. (375 aa)
FGAFibrinogen alpha chain. (909 aa)
GNAQG protein subunit alpha q. (313 aa)
FERMT3Fermitin family member 3. (663 aa)
RDH13Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (208 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (380 aa)
PLA2G4DPhospholipase A2. (794 aa)
P2RY12Purinergic receptor P2Y12. (342 aa)
ENSCANP00000003071SER_THR_PHOSPHATASE domain-containing protein. (146 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (642 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1257 aa)
PTGIRProstaglandin I2 receptor. (386 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
MYL12AMyosin light chain 12A. (177 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (709 aa)
GP9Glycoprotein IX platelet. (177 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1039 aa)
MYLKMyosin light chain kinase. (1914 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1471 aa)
POTEEANK_REP_REGION domain-containing protein; Belongs to the actin family. (952 aa)
MYL12BMyosin light chain 12B. (172 aa)
RDH14Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (976 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
TBXAS1Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (580 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
FCGR2AUncharacterized protein. (316 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1071 aa)
GNA13G protein subunit alpha 13. (282 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
PLA2G4CPhospholipase A2 group IVC. (551 aa)
FGGFibrinogen gamma chain. (453 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
PTK6Tyrosine-protein kinase. (451 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (413 aa)
PLA2G4BPhospholipase A2. (781 aa)
LYNTyrosine-protein kinase. (512 aa)
RAP1BUncharacterized protein. (184 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (238 aa)
SRCTyrosine-protein kinase. (458 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
RASGRP2RAS guanyl releasing protein 2. (609 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
ACTG1Uncharacterized protein. (376 aa)
MAPK13Mitogen-activated protein kinase. (491 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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