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| | TRPM2 | Transient receptor potential cation channel subfamily M member 2. (1343 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1240 aa) |
| | ARRDC5 | Arrestin domain containing 5. (342 aa) |
| | GIMAP7 | GTPase, IMAP family member 7. (279 aa) |
| | GAS7 | Growth arrest specific 7. (417 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa) |
| | ENSCANP00000002796 | Uncharacterized protein. (232 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (536 aa) |
| | STING1 | Transmembrane protein 173. (379 aa) |
| | TRPM7 | Transient receptor potential cation channel subfamily M member 7. (1848 aa) |
| | ATL3 | Atlastin GTPase 3. (544 aa) |
| | TP53BP1 | Tumor protein p53 binding protein 1. (1977 aa) |
| | GBP2 | Guanylate binding protein 2. (591 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | ENSCANP00000005141 | MPN domain-containing protein. (217 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | ENSCANP00000005382 | Thioredoxin domain-containing protein. (185 aa) |
| | GBP1 | Guanylate binding protein 1. (590 aa) |
| | GIMAP2 | GTPase, IMAP family member 2. (337 aa) |
| | CARD6 | Caspase recruitment domain family member 6. (1038 aa) |
| | TANK | TRAF family member associated NFKB activator. (425 aa) |
| | ENSCANP00000006328 | Defensin_propep domain-containing protein. (94 aa) |
| | CCL2 | C-C motif chemokine. (99 aa) |
| | ENSCANP00000006631 | Uncharacterized protein. (95 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (540 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (399 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa) |
| | ATL1 | Atlastin GTPase 1. (558 aa) |
| | LOC105514811 | Uncharacterized protein. (499 aa) |
| | NEK7 | NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa) |
| | URGCP | Upregulator of cell proliferation. (927 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | TRIM14 | Tripartite motif containing 14. (445 aa) |
| | CYBB | Cytochrome b-245 beta chain. (570 aa) |
| | RHOC | Ras homolog family member C. (193 aa) |
| | SGIP1 | SH3 domain GRB2 like endophilin interacting protein 1. (828 aa) |
| | ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (180 aa) |
| | ARRDC4 | Arrestin domain containing 4. (376 aa) |
| | HSP90AA1 | Heat shock protein 90 alpha family class A member 1. (821 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (625 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | LOC105503422 | DEFENSIN domain-containing protein. (94 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) |
| | JAK1 | Tyrosine-protein kinase. (1159 aa) |
| | MCUB | Mitochondrial calcium uniporter dominant negative beta subunit. (303 aa) |
| | CASP4 | Caspase 4; Belongs to the peptidase C14A family. (377 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | CARD18 | Caspase recruitment domain family member 18. (91 aa) |
| | RNF144A | RBR-type E3 ubiquitin transferase. (292 aa) |
| | ENSCANP00000015227 | Uncharacterized protein. (355 aa) |
| | ANKIB1 | RBR-type E3 ubiquitin transferase. (1089 aa) |
| | ARHGEF10L | Rho guanine nucleotide exchange factor 10 like. (1277 aa) |
| | ARHGEF33 | Rho guanine nucleotide exchange factor 33. (798 aa) |
| | LPP | LIM domain containing preferred translocation partner in lipoma. (611 aa) |
| | MAVS | Uncharacterized protein. (401 aa) |
| | GBP6 | GB1/RHD3-type G domain-containing protein. (633 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (325 aa) |
| | GPRC6A | G protein-coupled receptor class C group 6 member A. (928 aa) |
| | CEP78 | Centrosomal protein 78. (802 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (200 aa) |
| | MCU | Mitochondrial calcium uniporter. (302 aa) |
| | LOC105501293 | C-X-C motif chemokine. (107 aa) |
| | LOC105511316 | AIG1-type G domain-containing protein. (307 aa) |
| | GIMAP1 | GTPase, IMAP family member 1. (306 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | ARHGEF17 | Rho guanine nucleotide exchange factor 17. (1934 aa) |
| | GIMAP6 | GTPase, IMAP family member 6. (362 aa) |
| | MFN2 | Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (387 aa) |
| | SUGT1 | SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (364 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1035 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (369 aa) |
| | TRPV2 | Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa) |
| | DEFA1B | DEFENSIN domain-containing protein. (94 aa) |
| | IFNAR2 | Uncharacterized protein. (516 aa) |
| | NEK6 | NIMA related kinase 6; Belongs to the protein kinase superfamily. (347 aa) |
| | NLRP10 | NLR family pyrin domain containing 10. (636 aa) |
| | ZRANB1 | Zinc finger RANBP2-type containing 1. (734 aa) |
| | MEFV | MEFV innate immuity regulator, pyrin. (778 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | RNASEL | Ribonuclease L. (726 aa) |
| | FCHO2 | FCH domain only 2. (809 aa) |
| | TXN2 | Thioredoxin 2. (166 aa) |
| | NLRC5 | NLR family CARD domain containing 5. (1866 aa) |
| | TRIP6 | Thyroid hormone receptor interactor 6. (476 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa) |
| | BRCC3 | MPN domain-containing protein. (295 aa) |
| | HSP90AB1 | Heat shock protein 90 alpha family class B member 1. (724 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (752 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (491 aa) |
| | LRRC71 | Leucine rich repeat containing 71. (559 aa) |
| | GABARAPL2 | GABA type A receptor associated protein like 2. (117 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (518 aa) |
| | LOC105517738 | VWFA domain-containing protein. (587 aa) |
| | ARRDC2 | Arrestin domain containing 2. (386 aa) |
| | VDAC2 | Voltage dependent anion channel 2. (308 aa) |
| | NLRP7 | NLR family pyrin domain containing 7. (889 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa) |
| | TXNIP | Thioredoxin interacting protein. (391 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | GIMAP8 | GTPase, IMAP family member 8. (665 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa) |
| | ENSCANP00000030691 | Uncharacterized protein. (78 aa) |
| | XKRX | XK-related protein. (449 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (438 aa) |
| | PSTPIP1 | Proline-serine-threonine phosphatase interacting protein 1. (416 aa) |
| | LOC105515285 | HATPase_c domain-containing protein. (711 aa) |
| | ARIH1 | RBR-type E3 ubiquitin transferase. (467 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1040 aa) |
| | LOC105500957 | Uncharacterized protein; Belongs to the peptidase C14A family. (406 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2697 aa) |
| | LOC105527571 | Uncharacterized protein. (255 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | ARRDC1 | Arrestin domain containing 1. (419 aa) |
| | VCPIP1 | Valosin containing protein interacting protein 1. (1222 aa) |
| | IRF7 | Interferon regulatory factor 7. (503 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | GABARAPL1 | GABA type A receptor associated protein like 1. (146 aa) |
| | RNF144B | RBR-type E3 ubiquitin transferase. (303 aa) |
| | LOC105525759 | Theta defensin subunit C. (76 aa) |
| | ENSCANP00000028682 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (198 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (636 aa) |
| | PYDC1 | Pyrin domain containing 1. (77 aa) |
| | LRRC74A | Leucine rich repeat containing 74A. (488 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (306 aa) |
| | TBK1 | TANK binding kinase 1. (713 aa) |
| | STAT2 | Signal transducer and activator of transcription. (708 aa) |
| | LOC105503376 | Thioredoxin domain-containing protein. (104 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthetase 2. (719 aa) |
| | LOC105503436 | Uncharacterized protein. (198 aa) |
| | ANTXR2 | Anthrax toxin receptor; Belongs to the ATR family. (488 aa) |
| | BCL2L1 | BCL2 like 1. (233 aa) |
| | PKN2 | Protein kinase N2. (983 aa) |
| | OTUD7A | OTU deubiquitinase 7A. (606 aa) |
| | LRRC31 | Leucine rich repeat containing 31. (552 aa) |
| | RNF217 | RBR-type E3 ubiquitin transferase. (475 aa) |
| | OAS3 | 2'-5'-oligoadenylate synthetase 3. (1090 aa) |
| | NLRP2 | NLR family pyrin domain containing 2. (957 aa) |
| | ATL2 | Atlastin GTPase 2. (536 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa) |
| | GBP3 | Guanylate binding protein 3. (595 aa) |
| | OTUD7B | OTU deubiquitinase 7B. (843 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | CASP12 | Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (336 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | CTSB | Cathepsin B; Belongs to the peptidase C1 family. (339 aa) |
| | ANTXR1 | Anthrax toxin receptor; Belongs to the ATR family. (506 aa) |
| | ENSCANP00000018496 | Uncharacterized protein. (237 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (550 aa) |
| | PKN1 | Protein kinase N1. (898 aa) |
| | NLRP6 | NLR family pyrin domain containing 6. (1041 aa) |
| | ARRDC3 | Arrestin domain containing 3. (414 aa) |
| | ATG16L1 | Autophagy related 16 like 1. (621 aa) |
| | CUL9 | Cullin 9; Belongs to the cullin family. (2517 aa) |
| | TYK2 | Tyrosine-protein kinase. (1187 aa) |
| | FCHO1 | FCH domain only 1. (942 aa) |
| | NFKBIB | NFKB inhibitor beta. (321 aa) |
| | LOC105515531 | HATPase_c domain-containing protein. (644 aa) |
| | LOC105517732 | VWFA domain-containing protein. (599 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | NLRP9 | NLR family pyrin domain containing 9. (876 aa) |
| | NLRP12 | NLR family pyrin domain containing 12. (1033 aa) |
| | DHX33 | DEAH-box helicase 33. (706 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | GIMAP4 | GTPase, IMAP family member 4. (329 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthetase 1. (400 aa) |
| | TXN | Thioredoxin; Belongs to the thioredoxin family. (105 aa) |
| | NLRC3 | NLR family CARD domain containing 3. (1097 aa) |
| | TICAM1 | Toll like receptor adaptor molecule 1. (517 aa) |
| | TXNDC8 | Thioredoxin domain containing 8. (127 aa) |
| | LOC105525760 | Defensin_propep domain-containing protein; Belongs to the alpha-defensin family. (76 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (790 aa) |
| | SHARPIN | SHANK associated RH domain interactor. (257 aa) |
| | NLRP14 | NLR family pyrin domain containing 14. (1092 aa) |
| | STAT1 | Signal transducer and activator of transcription. (765 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (343 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | GBP7 | Guanylate binding protein 7. (638 aa) |
| | LOC105514812 | Uncharacterized protein. (440 aa) |
| | GABARAP | GABA type A receptor-associated protein. (117 aa) |
| | PANX1 | Pannexin; Structural component of the gap junctions and the hemichannels. (426 aa) |
| | VDAC1 | Voltage dependent anion channel 1. (289 aa) |
| | LOC105521852 | GB1/RHD3-type G domain-containing protein. (633 aa) |
| | NLRP13 | NLR family pyrin domain containing 13. (1021 aa) |
| | RNF31 | Uncharacterized protein. (1072 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (604 aa) |
| | NAMPT | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (486 aa) |
| | CXCL1 | C-X-C motif chemokine. (107 aa) |
| | CASP5 | Caspase 5; Belongs to the peptidase C14A family. (446 aa) |
| | ENSCANP00000024933 | Uncharacterized protein. (94 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (372 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (970 aa) |
| | LRRC7 | Leucine rich repeat containing 7. (1542 aa) |
| | IRF3 | Interferon regulatory factor 3. (426 aa) |
| | IRF9 | Interferon regulatory factor 9. (393 aa) |
| | CXCL2 | C-X-C motif chemokine. (107 aa) |
| | LRRC74B | Leucine rich repeat containing 74B. (366 aa) |
| | ENSCANP00000024192 | HATPase_c domain-containing protein. (669 aa) |
| | LOC105517733 | VWFA domain-containing protein. (454 aa) |
| | ERBIN | Erbb2 interacting protein. (1418 aa) |
| | MNDA | Myeloid cell nuclear differentiation antigen. (407 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | CYBA | Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa) |
| | ARHGEF10 | Rho guanine nucleotide exchange factor 10. (1319 aa) |
| | LOC105501334 | Thioredoxin; Belongs to the thioredoxin family. (101 aa) |
| | IFI16 | Interferon gamma inducible protein 16. (729 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa) |
| | PYHIN1 | Pyrin and HIN domain family member 1. (492 aa) |
| | AIM2 | Absent in melanoma 2. (343 aa) |
| | NAIP | NLR family apoptosis inhibitory protein. (1369 aa) |
| | CARD16 | Caspase recruitment domain family member 16. (197 aa) |
| | RNH1 | Ribonuclease/angiogenin inhibitor 1. (456 aa) |
| | NLRP1 | NLR family pyrin domain containing 1. (1419 aa) |
| | MFN1 | Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (696 aa) |
| | LRRC34 | Leucine rich repeat containing 34. (415 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | NLRC4 | NLR family CARD domain containing 4. (1024 aa) |
| | LOC105509062 | Uncharacterized protein. (647 aa) |
| | CASR | Calcium sensing receptor. (1088 aa) |
| | CAMP | Cathelicidin antimicrobial peptide. (173 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | XIAP | X-linked inhibitor of apoptosis. (497 aa) |
| | RNF19B | Ring finger protein 19B. (486 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | ENSCANP00000038735 | GB1/RHD3-type G domain-containing protein. (255 aa) |
| | LOC105525256 | DEFSN domain-containing protein. (64 aa) |
| | PSTPIP2 | Proline-serine-threonine phosphatase interacting protein 2. (308 aa) |
| | IL6 | Interleukin 6. (214 aa) |
| | ENSCANP00000038043 | Uncharacterized protein. (107 aa) |
| | NUGGC | Nuclear GTPase, germinal center associated. (795 aa) |
| | LOC105525255 | Uncharacterized protein. (67 aa) |
| | RNF19A | RBR-type E3 ubiquitin transferase. (838 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | NLRX1 | NLR family member X1. (972 aa) |
