62 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCANP00000039946	Uncharacterized protein. (222 aa)
	RIPK1	Receptor interacting serine/threonine kinase 1. (625 aa)
	PIN1	Peptidyl-prolyl cis-trans isomerase. (156 aa)
	TRIM47	Tripartite motif containing 47. (498 aa)
	MAPK9	Mitogen-activated protein kinase. (399 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
	CASP8	Caspase 8; Belongs to the peptidase C14A family. (538 aa)
	FADD	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (200 aa)
	RNF125	Ring finger protein 125. (232 aa)
	MAPK12	Mitogen-activated protein kinase. (325 aa)
	ENSCANP00000013745	Coilin_N domain-containing protein. (508 aa)
	MAVS	Uncharacterized protein. (401 aa)
	DHX58	DExH-box helicase 58. (678 aa)
	COIL	Coilin. (575 aa)
	DDX3X	DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (721 aa)
	IFIH1	Interferon induced with helicase C domain 1. (1025 aa)
	DDX58	DExD/H-box helicase 58. (925 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
	MAPK10	Mitogen-activated protein kinase. (550 aa)
	NFKBIB	NFKB inhibitor beta. (321 aa)
	TRADD	TNFRSF1A associated via death domain. (308 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	ISG15	ISG15 ubiquitin like modifier. (165 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	CYLD	CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
	CXCL10	C-X-C motif chemokine. (98 aa)
	TRIM65	Tripartite motif containing 65. (381 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	IRF3	Interferon regulatory factor 3. (426 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (970 aa)
	MAP3K1	Mitogen-activated protein kinase kinase kinase 1. (1356 aa)
	CASP10	Caspase 10; Belongs to the peptidase C14A family. (484 aa)
	IKBKE	Inhibitor of nuclear factor kappa B kinase subunit epsilon. (636 aa)
	TRIM25	Tripartite motif containing 25. (630 aa)
	TRAF3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
	IFNB1	Interferon beta 1. (187 aa)
	IRF7	Interferon regulatory factor 7. (503 aa)
	CXCL8	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
	AZI2	5-azacytidine induced 2. (394 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (548 aa)
	SIKE1	Suppressor of IKBKE 1. (211 aa)
	FGFR1OP2	FGFR1 oncogene partner 2. (253 aa)
	MAPK13	Mitogen-activated protein kinase. (491 aa)
	IL12B	Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
	IKBKG	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (369 aa)
	IL12A	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
	ATG12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (180 aa)
	NLRX1	NLR family member X1. (972 aa)
	IFNE	Interferon epsilon. (196 aa)
	TRAF2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
	TKFC	Triokinase and FMN cyclase. (575 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	LOC105503436	Uncharacterized protein. (198 aa)
	TBK1	TANK binding kinase 1. (713 aa)
	MAPK11	Mitogen-activated protein kinase. (306 aa)
	STING1	Transmembrane protein 173. (379 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
	TANK	TRAF family member associated NFKB activator. (425 aa)
	OTUD5	OTU deubiquitinase 5. (349 aa)
	NFKBIA	NFKB inhibitor alpha. (317 aa)
	RNF135	Ring finger protein 135. (337 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG5	ENSCANP00000036888	ENSCANP00000023717	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	CASP10	ENSCANP00000036888	ENSCANP00000026452	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Caspase 10; Belongs to the peptidase C14A family.	0.400
ATG12	CASP8	ENSCANP00000036888	ENSCANP00000012395	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Caspase 8; Belongs to the peptidase C14A family.	0.532
ATG12	DDX58	ENSCANP00000036888	ENSCANP00000017005	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	DExD/H-box helicase 58.	0.939
ATG12	DHX58	ENSCANP00000036888	ENSCANP00000015187	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	DExH-box helicase 58.	0.656
ATG12	FADD	ENSCANP00000036888	ENSCANP00000013072	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.690
ATG12	IFIH1	ENSCANP00000036888	ENSCANP00000016665	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Interferon induced with helicase C domain 1.	0.841
ATG12	MAVS	ENSCANP00000036888	ENSCANP00000014113	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein.	0.944
ATG12	NLRX1	ENSCANP00000036888	ENSCANP00000036916	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	NLR family member X1.	0.621
ATG5	ATG12	ENSCANP00000023717	ENSCANP00000036888	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ATG5	CASP10	ENSCANP00000023717	ENSCANP00000026452	Autophagy protein 5; Involved in autophagic vesicle formation.	Caspase 10; Belongs to the peptidase C14A family.	0.523
ATG5	CASP8	ENSCANP00000023717	ENSCANP00000012395	Autophagy protein 5; Involved in autophagic vesicle formation.	Caspase 8; Belongs to the peptidase C14A family.	0.675
ATG5	DDX58	ENSCANP00000023717	ENSCANP00000017005	Autophagy protein 5; Involved in autophagic vesicle formation.	DExD/H-box helicase 58.	0.939
ATG5	DHX58	ENSCANP00000023717	ENSCANP00000015187	Autophagy protein 5; Involved in autophagic vesicle formation.	DExH-box helicase 58.	0.651
ATG5	FADD	ENSCANP00000023717	ENSCANP00000013072	Autophagy protein 5; Involved in autophagic vesicle formation.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.757
ATG5	IFIH1	ENSCANP00000023717	ENSCANP00000016665	Autophagy protein 5; Involved in autophagic vesicle formation.	Interferon induced with helicase C domain 1.	0.810
ATG5	MAVS	ENSCANP00000023717	ENSCANP00000014113	Autophagy protein 5; Involved in autophagic vesicle formation.	Uncharacterized protein.	0.943
ATG5	NLRX1	ENSCANP00000023717	ENSCANP00000036916	Autophagy protein 5; Involved in autophagic vesicle formation.	NLR family member X1.	0.638
ATG5	RIPK1	ENSCANP00000023717	ENSCANP00000008143	Autophagy protein 5; Involved in autophagic vesicle formation.	Receptor interacting serine/threonine kinase 1.	0.539
AZI2	CHUK	ENSCANP00000030873	ENSCANP00000005285	5-azacytidine induced 2.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.659