STRINGSTRING
RORA RORA IL2RB IL2RB STAT5B STAT5B MAPK12 MAPK12 IL1R1 IL1R1 HLA-DRA HLA-DRA IFNG IFNG RXRG RXRG MAPK3 MAPK3 CD247 CD247 IL6ST IL6ST LOC105502761 LOC105502761 JAK1 JAK1 LOC105514240 LOC105514240 RUNX1 RUNX1 RARA RARA IL2RA IL2RA PPP3R1 PPP3R1 HLA-DQB1 HLA-DQB1 MAPK10 MAPK10 FOS FOS STAT6 STAT6 IL12RB1 IL12RB1 TYK2 TYK2 NFKBIB NFKBIB LOC105515531 LOC105515531 PPP3R2 PPP3R2 LOC105513801 LOC105513801 IL17F IL17F MAPK8 MAPK8 HLA-DRB5 HLA-DRB5 HLA-DQA1 HLA-DQA1 MTOR MTOR TRAC TRAC STAT3 STAT3 IL4 IL4 IRF4 IRF4 LOC105513786 LOC105513786 GATA3 GATA3 ENSCANP00000024192 ENSCANP00000024192 NFKB1 NFKB1 IL2 IL2 IFNGR1 IFNGR1 IL27RA IL27RA MAPK1 MAPK1 STAT1 STAT1 LOC105513798 LOC105513798 IL21 IL21 RORC RORC FOXP3 FOXP3 RXRB RXRB HIF1A HIF1A PPP3CA PPP3CA SMAD4 SMAD4 CD3D CD3D TGFBR1 TGFBR1 LOC105515285 LOC105515285 HLA-DOB HLA-DOB IL6R IL6R IL1B IL1B JUN JUN LOC105501359 LOC105501359 IL22 IL22 RELA RELA MAPK13 MAPK13 IL2RG IL2RG HSP90AB1 HSP90AB1 CD3G CD3G JAK2 JAK2 IL17A IL17A HLA-DMA HLA-DMA IKBKG IKBKG SMAD2 SMAD2 CD4 CD4 CD3E CD3E HLA-DOA HLA-DOA IFNGR2 IFNGR2 ZAP70 ZAP70 AHR AHR LCK LCK IL6 IL6 LAT LAT PPP3CC PPP3CC MAPK14 MAPK14 IL4R IL4R JAK3 JAK3 IL23A IL23A LOC105509062 LOC105509062 SMAD3 SMAD3 MAPK11 MAPK11 DUSP15 DUSP15 LOC105501360 LOC105501360 TGFBR2 TGFBR2 TRAV22 TRAV22 CHUK CHUK NFKBIE NFKBIE IL1RAP IL1RAP PPP3CB PPP3CB RXRA RXRA IL23R IL23R NFKBIA NFKBIA LOC105501361 LOC105501361 HSP90AA1 HSP90AA1 TBX21 TBX21 NFATC2 NFATC2 PRKCQ PRKCQ TGFB1 TGFB1 NFATC3 NFATC3 NFATC1 NFATC1 MAPK9 MAPK9 IKBKB IKBKB IL21R IL21R PLCG1 PLCG1 STAT5A STAT5A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RORARAR related orphan receptor A. (555 aa)
IL2RBInterleukin 2 receptor subunit beta. (551 aa)
STAT5BSignal transducer and activator of transcription. (756 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
RXRGRetinoid X receptor gamma. (463 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
CD247CD247 molecule. (163 aa)
IL6STInterleukin 6 signal transducer. (860 aa)
LOC105502761Ig-like domain-containing protein. (283 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
LOC105514240Ig-like domain-containing protein. (256 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (455 aa)
RARARetinoic acid receptor alpha. (478 aa)
IL2RAInterleukin 2 receptor subunit alpha. (272 aa)
PPP3R1Uncharacterized protein. (189 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (269 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (662 aa)
TYK2Tyrosine-protein kinase. (1187 aa)
NFKBIBNFKB inhibitor beta. (321 aa)
LOC105515531HATPase_c domain-containing protein. (644 aa)
PPP3R2Protein phosphatase 3 regulatory subunit B, beta. (174 aa)
LOC105513801Ig-like domain-containing protein. (279 aa)
IL17FInterleukin 17F. (163 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
HLA-DRB5Major histocompatibility complex, class II, DR beta 5. (266 aa)
HLA-DQA1Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (256 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
TRACT cell receptor alpha constant. (110 aa)
STAT3Signal transducer and activator of transcription. (795 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
IRF4Interferon regulatory factor 4. (450 aa)
LOC105513786Ig-like domain-containing protein. (266 aa)
GATA3GATA binding protein 3. (444 aa)
ENSCANP00000024192HATPase_c domain-containing protein. (669 aa)
NFKB1Nuclear factor kappa B subunit 1. (970 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
IFNGR1Interferon gamma receptor 1. (489 aa)
IL27RAInterleukin 27 receptor subunit alpha. (636 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
STAT1Signal transducer and activator of transcription. (765 aa)
LOC105513798Ig-like domain-containing protein. (263 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
RORCRAR related orphan receptor C. (560 aa)
FOXP3Forkhead box P3. (441 aa)
RXRBRetinoid X receptor beta. (539 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (827 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CD3DCD3d molecule. (171 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
LOC105515285HATPase_c domain-containing protein. (711 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (273 aa)
IL6RInterleukin 6 receptor. (568 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
LOC105501359Ig-like domain-containing protein. (281 aa)
IL22Interleukin 22. (179 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
MAPK13Mitogen-activated protein kinase. (491 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
CD3GCD3g molecule. (181 aa)
JAK2Tyrosine-protein kinase. (1139 aa)
IL17AInterleukin 17A. (155 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (369 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
CD4CD4 molecule. (458 aa)
CD3ECD3e molecule. (198 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
IFNGR2Interferon gamma receptor 2. (231 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
AHRUncharacterized protein. (846 aa)
LCKTyrosine-protein kinase. (539 aa)
IL6Interleukin 6. (214 aa)
LATLinker for activation of T cells. (254 aa)
PPP3CCSerine/threonine-protein phosphatase. (499 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
IL4RInterleukin 4 receptor. (824 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
IL23AInterleukin 23 subunit alpha. (200 aa)
LOC105509062Uncharacterized protein. (647 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
DUSP15Dual specificity phosphatase 15; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (270 aa)
LOC105501360Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
TRAV22T cell receptor alpha variable 22. (147 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
NFKBIENFKB inhibitor epsilon. (487 aa)
IL1RAPInterleukin 1 receptor accessory protein. (687 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
RXRARetinoid X receptor alpha. (471 aa)
IL23RInterleukin 23 receptor. (629 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
LOC105501361Ig-like domain-containing protein. (296 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (821 aa)
TBX21T-box transcription factor 21. (335 aa)
NFATC2Nuclear factor of activated T cells 2. (923 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
NFATC3Nuclear factor of activated T cells 3. (1067 aa)
NFATC1Nuclear factor of activated T cells 1. (815 aa)
MAPK9Mitogen-activated protein kinase. (399 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
IL21RInterleukin 21 receptor. (538 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
STAT5ASignal transducer and activator of transcription. (789 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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