STRINGSTRING
CAMK2A CAMK2A ITPR2 ITPR2 PLCB1 PLCB1 GRIN2B GRIN2B BRAF BRAF MAP2K1 MAP2K1 RAP1B RAP1B CAMK2G CAMK2G PLCB4 PLCB4 PVALEF PVALEF RPS6KA6 RPS6KA6 CACNA1C CACNA1C ATF4 ATF4 CREBBP CREBBP ITPR1 ITPR1 PPP3CA PPP3CA ENSCANP00000028447 ENSCANP00000028447 CALML4 CALML4 ADCY8 ADCY8 MAPK1 MAPK1 RPS6KA3 RPS6KA3 RAP1A RAP1A GRIN2C GRIN2C CALM2 CALM2 PPP1CC PPP1CC CSDE1 CSDE1 ITPR3 ITPR3 PRKCB PRKCB ARAF ARAF ARSI ARSI ENSCANP00000021474 ENSCANP00000021474 PPP3R2 PPP3R2 ENSCANP00000019829 ENSCANP00000019829 GRIN1 GRIN1 PPP3R1 PPP3R1 RAF1 RAF1 PRKACA PRKACA CAMK2B CAMK2B CAMK2D CAMK2D MAPK3 MAPK3 GRM1 GRM1 RPS6KA1 RPS6KA1 LOC105504658 LOC105504658 CALM3 CALM3 ENSCANP00000014775 ENSCANP00000014775 EP300 EP300 CALML6 CALML6 GRIA2 GRIA2 PPP1CB PPP1CB MAP2K2 MAP2K2 PRKCG PRKCG ENSCANP00000009565 ENSCANP00000009565 ENSCANP00000009406 ENSCANP00000009406 PPP1R1A PPP1R1A PRKACB PRKACB PPP3CB PPP3CB KRAS KRAS GNAQ GNAQ HRAS HRAS RAPGEF3 RAPGEF3 GRM5 GRM5 CALML3 CALML3 ENSCANP00000003071 ENSCANP00000003071 CALM1 CALM1 GRIN2A GRIN2A PLCB2 PLCB2 PRKCA PRKCA PPP1CA PPP1CA GRIN2D GRIN2D ERAS ERAS GRIA1 GRIA1 CAMK4 CAMK4 PLCB3 PLCB3 PPP3CC PPP3CC ENSCANP00000039354 ENSCANP00000039354 RPS6KA2 RPS6KA2 ADCY1 ADCY1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (747 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
RAP1BUncharacterized protein. (184 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (552 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
RPS6KA6Ribosomal protein S6 kinase. (745 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2134 aa)
ATF4Activating transcription factor 4. (351 aa)
CREBBPCREB binding protein. (2117 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2697 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
ENSCANP00000028447Uncharacterized protein; Belongs to the calmodulin family. (173 aa)
CALML4Calmodulin like 4. (192 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
RPS6KA3Ribosomal protein S6 kinase. (742 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1005 aa)
CALM2Calmodulin 2. (149 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
CSDE1Uncharacterized protein. (844 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (587 aa)
ARSIArylsulfatase family member I. (569 aa)
ENSCANP00000021474Uncharacterized protein. (136 aa)
PPP3R2Protein phosphatase 3 regulatory subunit B, beta. (174 aa)
ENSCANP00000019829Uncharacterized protein. (98 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (834 aa)
PPP3R1Uncharacterized protein. (189 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (345 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
GRM1Glutamate metabotropic receptor 1. (1194 aa)
RPS6KA1Ribosomal protein S6 kinase. (728 aa)
LOC105504658Uncharacterized protein. (571 aa)
CALM3Calmodulin 3. (149 aa)
ENSCANP00000014775Uncharacterized protein. (130 aa)
EP300E1A binding protein p300. (2409 aa)
CALML6Calmodulin like 6. (181 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (369 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
ENSCANP00000009565Uncharacterized protein. (651 aa)
ENSCANP00000009406Uncharacterized protein; Belongs to the calmodulin family. (163 aa)
PPP1R1AProtein phosphatase 1 regulatory inhibitor subunit 1A. (171 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
GNAQG protein subunit alpha q. (313 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
GRM5Glutamate metabotropic receptor 5. (1212 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
ENSCANP00000003071SER_THR_PHOSPHATASE domain-containing protein. (146 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (674 aa)
ERASES cell expressed Ras. (233 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (448 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa)
PPP3CCSerine/threonine-protein phosphatase. (499 aa)
ENSCANP00000039354Protein kinase domain-containing protein. (353 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (976 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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