STRINGSTRING
ADCY2 ADCY2 GABBR2 GABBR2 ENSCANP00000009406 ENSCANP00000009406 LOC105503047 LOC105503047 HSP90AA1 HSP90AA1 NCOA3 NCOA3 LOC105521523 LOC105521523 PRKACB PRKACB ENSCANP00000007054 ENSCANP00000007054 KRAS KRAS GNAQ GNAQ TGFA TGFA KCNJ9 KCNJ9 KRT40 KRT40 LOC105507346 LOC105507346 HBEGF HBEGF KRT28 KRT28 GRB2 GRB2 LOC105509062 LOC105509062 LOC105512416 LOC105512416 SRC SRC PLCB3 PLCB3 KRT13 KRT13 ENSCANP00000039354 ENSCANP00000039354 KRT10 KRT10 KRT24 KRT24 KCNJ3 KCNJ3 KRT35 KRT35 CREB3L3 CREB3L3 ADCY1 ADCY1 ITPR2 ITPR2 PIK3CD PIK3CD PLCB1 PLCB1 HSPA2 HSPA2 SOS2 SOS2 ESR1 ESR1 CREB3 CREB3 PIK3R3 PIK3R3 ENSCANP00000035282 ENSCANP00000035282 MAP2K1 MAP2K1 HSP90B1 HSP90B1 CREB3L2 CREB3L2 PLCB4 PLCB4 PVALEF PVALEF ATF6B ATF6B HSP90AB1 HSP90AB1 KCNJ6 KCNJ6 KRT12 KRT12 ENSCANP00000011682 ENSCANP00000011682 CREB5 CREB5 KRT33A KRT33A GNAI3 GNAI3 GNAI2 GNAI2 MAP2K2 MAP2K2 GABBR1 GABBR1 TFF1 TFF1 KCNJ5 KCNJ5 KRT34 KRT34 CREB1 CREB1 CALML6 CALML6 KRT17 KRT17 AKT1 AKT1 NOS3 NOS3 CALM3 CALM3 LOC105504658 LOC105504658 LOC105500830 LOC105500830 GRM1 GRM1 MAPK3 MAPK3 KRT25 KRT25 NCOA1 NCOA1 PIK3CA PIK3CA RARA RARA ADCY9 ADCY9 KRT20 KRT20 PRKACA PRKACA EGFR EGFR RAF1 RAF1 FOS FOS GNAO1 GNAO1 ENSCANP00000019829 ENSCANP00000019829 LOC105515531 LOC105515531 KRT18 KRT18 ESR2 ESR2 KRT15 KRT15 GNAS GNAS KRT32 KRT32 KRT39 KRT39 PIK3R1 PIK3R1 LOC105503927 LOC105503927 AKT2 AKT2 PTRHD1 PTRHD1 GNAI1 GNAI1 ITPR3 ITPR3 ADCY5 ADCY5 CSDE1 CSDE1 SHC1 SHC1 ENSCANP00000024192 ENSCANP00000024192 GPER1 GPER1 SHC2 SHC2 CALM2 CALM2 CTSD CTSD FKBP4 FKBP4 KRT9 KRT9 KRT36 KRT36 ADCY3 ADCY3 MAPK1 MAPK1 CREB3L4 CREB3L4 SP1 SP1 ADCY8 ADCY8 SHC3 SHC3 CALML4 CALML4 KRT14 KRT14 KRT38 KRT38 EBAG9 EBAG9 AKT3 AKT3 ENSCANP00000028447 ENSCANP00000028447 CREB3L1 CREB3L1 KRT31 KRT31 HSPA1L HSPA1L ITPR1 ITPR1 NCOA2 NCOA2 KRT27 KRT27 LOC105515285 LOC105515285 PIK3CB PIK3CB KRT33B KRT33B HSPA8 HSPA8 ERAS ERAS LOC105523208 LOC105523208 HSPA6 HSPA6 POMC POMC CCDC170 CCDC170 ENSCANP00000002453 ENSCANP00000002453 PLCB2 PLCB2 CALM1 CALM1 LOC105522500 LOC105522500 KRT26 KRT26 KRT37 KRT37 CALML3 CALML3 KRT16 KRT16 LOC105517986 LOC105517986 PRKCD PRKCD SHC4 SHC4 ATF2 ATF2 BCL2 BCL2 HRAS HRAS ADCY4 ADCY4 ADCY7 ADCY7 ADCY6 ADCY6 LOC105522998 LOC105522998 ATF4 ATF4 FKBP5 FKBP5 JUN JUN CEP152 CEP152 LOC105506399 LOC105506399 PIK3R2 PIK3R2 KRT23 KRT23 SOS1 SOS1 MMP9 MMP9 OPRM1 OPRM1 PGR PGR
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1014 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (893 aa)
ENSCANP00000009406Uncharacterized protein; Belongs to the calmodulin family. (163 aa)
LOC105503047IF rod domain-containing protein; Belongs to the intermediate filament family. (430 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (821 aa)
NCOA3Nuclear receptor coactivator. (1425 aa)
LOC105521523Uncharacterized protein; Belongs to the heat shock protein 70 family. (599 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ENSCANP00000007054IF rod domain-containing protein; Belongs to the intermediate filament family. (431 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
GNAQG protein subunit alpha q. (313 aa)
TGFATransforming growth factor alpha. (166 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (475 aa)
KRT40Keratin 40; Belongs to the intermediate filament family. (378 aa)
LOC105507346IF rod domain-containing protein; Belongs to the intermediate filament family. (430 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
KRT28Keratin 28; Belongs to the intermediate filament family. (464 aa)
GRB2Uncharacterized protein. (156 aa)
LOC105509062Uncharacterized protein. (647 aa)
LOC105512416IF rod domain-containing protein; Belongs to the intermediate filament family. (415 aa)
SRCTyrosine-protein kinase. (458 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa)
KRT13IF rod domain-containing protein; Belongs to the intermediate filament family. (454 aa)
ENSCANP00000039354Protein kinase domain-containing protein. (353 aa)
KRT10Keratin 10; Belongs to the intermediate filament family. (525 aa)
KRT24Keratin 24; Belongs to the intermediate filament family. (522 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
KRT35Keratin 35; Belongs to the intermediate filament family. (455 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (415 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (976 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1071 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (602 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
ENSCANP00000035282IF rod domain-containing protein; Belongs to the intermediate filament family. (426 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
HSP90B1Heat shock protein 90 beta family member 1. (804 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (461 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
ATF6BActivating transcription factor 6 beta. (690 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
KRT12Keratin 12; Belongs to the intermediate filament family. (495 aa)
ENSCANP00000011682IF rod domain-containing protein; Belongs to the intermediate filament family. (422 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
KRT33AKeratin 33A; Belongs to the intermediate filament family. (404 aa)
GNAI3G protein subunit alpha i3. (301 aa)
GNAI2G protein subunit alpha i2. (355 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (369 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (963 aa)
TFF1Trefoil factor 1. (83 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
KRT34Keratin 34; Belongs to the intermediate filament family. (394 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CALML6Calmodulin like 6. (181 aa)
KRT17Keratin 17; Belongs to the intermediate filament family. (432 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
CALM3Calmodulin 3. (149 aa)
LOC105504658Uncharacterized protein. (571 aa)
LOC105500830Uncharacterized protein; Belongs to the heat shock protein 70 family. (608 aa)
GRM1Glutamate metabotropic receptor 1. (1194 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
KRT25Keratin 25; Belongs to the intermediate filament family. (450 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RARARetinoic acid receptor alpha. (478 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
KRT20Keratin 20; Belongs to the intermediate filament family. (424 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (345 aa)
EGFRReceptor protein-tyrosine kinase. (1188 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
GNAO1G protein subunit alpha o1. (354 aa)
ENSCANP00000019829Uncharacterized protein. (98 aa)
LOC105515531HATPase_c domain-containing protein. (644 aa)
KRT18IF rod domain-containing protein; Belongs to the intermediate filament family. (353 aa)
ESR2Estrogen receptor 2. (530 aa)
KRT15Keratin 15; Belongs to the intermediate filament family. (456 aa)
GNASGNAS complex locus. (913 aa)
KRT32Keratin 32; Belongs to the intermediate filament family. (448 aa)
KRT39Keratin 39; Belongs to the intermediate filament family. (491 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
LOC105503927Uncharacterized protein; Belongs to the heat shock protein 70 family. (592 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
GNAI1G protein subunit alpha i1. (354 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1121 aa)
CSDE1Uncharacterized protein. (844 aa)
SHC1SHC adaptor protein 1. (584 aa)
ENSCANP00000024192HATPase_c domain-containing protein. (669 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa)
SHC2SHC adaptor protein 2. (381 aa)
CALM2Calmodulin 2. (149 aa)
CTSDPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (559 aa)
FKBP4Peptidylprolyl isomerase. (424 aa)
KRT9Keratin 9; Belongs to the intermediate filament family. (387 aa)
KRT36Keratin 36; Belongs to the intermediate filament family. (417 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1142 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (427 aa)
SP1Sp1 transcription factor. (718 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
SHC3SHC adaptor protein 3. (517 aa)
CALML4Calmodulin like 4. (192 aa)
KRT14Keratin 14; Belongs to the intermediate filament family. (477 aa)
KRT38Keratin 38; Belongs to the intermediate filament family. (452 aa)
EBAG9Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (258 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ENSCANP00000028447Uncharacterized protein; Belongs to the calmodulin family. (173 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
KRT31IF rod domain-containing protein; Belongs to the intermediate filament family. (416 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2697 aa)
NCOA2Nuclear receptor coactivator. (1468 aa)
KRT27Keratin 27; Belongs to the intermediate filament family. (459 aa)
LOC105515285HATPase_c domain-containing protein. (711 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
KRT33BKeratin 33B; Belongs to the intermediate filament family. (404 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
ERASES cell expressed Ras. (233 aa)
LOC105523208Uncharacterized protein. (380 aa)
HSPA6Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (576 aa)
POMCProopiomelanocortin. (251 aa)
CCDC170Coiled-coil domain containing 170. (715 aa)
ENSCANP00000002453Uncharacterized protein; Belongs to the heat shock protein 70 family. (529 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
LOC105522500IF rod domain-containing protein; Belongs to the intermediate filament family. (397 aa)
KRT26Keratin 26; Belongs to the intermediate filament family. (468 aa)
KRT37Keratin 37; Belongs to the intermediate filament family. (449 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
KRT16Keratin 16; Belongs to the intermediate filament family. (476 aa)
LOC105517986IF rod domain-containing protein; Belongs to the intermediate filament family. (430 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
SHC4SHC adaptor protein 4. (630 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1083 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
LOC105522998Uncharacterized protein. (693 aa)
ATF4Activating transcription factor 4. (351 aa)
FKBP5Peptidylprolyl isomerase. (457 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
CEP152Centrosomal protein 152. (1709 aa)
LOC105506399Uncharacterized protein. (246 aa)
PIK3R2Uncharacterized protein. (601 aa)
KRT23Keratin 23; Belongs to the intermediate filament family. (394 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1310 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
PGRProgesterone receptor. (799 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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