78 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IRS1	Insulin receptor substrate 1. (1243 aa)
	ENSCANP00000023157	MFS domain-containing protein. (216 aa)
	PRKAB1	Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
	STAT3	Signal transducer and activator of transcription. (795 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	AKT2	AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa)
	ENSCANP00000021381	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (443 aa)
	PRKAG3	Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	TRADD	TNFRSF1A associated via death domain. (308 aa)
	NFKBIB	NFKB inhibitor beta. (321 aa)
	PPARGC1A	PPARG coactivator 1 alpha. (798 aa)
	MAPK10	Mitogen-activated protein kinase. (550 aa)
	G6PC	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
	ACSL3	Acyl-CoA synthetase long chain family member 3. (720 aa)
	ADIPOR2	Adiponectin receptor 2. (386 aa)
	PCK1	Phosphoenolpyruvate carboxykinase 1. (622 aa)
	AGRP	Agouti related neuropeptide. (132 aa)
	RXRG	Retinoid X receptor gamma. (463 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (574 aa)
	ENSCANP00000011220	Uncharacterized protein. (277 aa)
	LEPR	Leptin receptor. (1163 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
	MAPK9	Mitogen-activated protein kinase. (399 aa)
	ADIPOR1	Adiponectin receptor 1. (258 aa)
	ACSL6	AMP-binding domain-containing protein. (722 aa)
	PRKAB2	Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
	CPT1B	Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
	G6PC3	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
	ACACB	Acetyl-CoA carboxylase beta. (2438 aa)
	NFKBIA	NFKB inhibitor alpha. (317 aa)
	RXRA	Retinoid X receptor alpha. (471 aa)
	ENSCANP00000006359	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (232 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (970 aa)
	NFKBIE	NFKB inhibitor epsilon. (487 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
	CAMKK2	Calcium/calmodulin dependent protein kinase kinase 2. (576 aa)
	NPY	Neuropeptide Y. (97 aa)
	SOCS3	Suppressor of cytokine signaling 3. (225 aa)
	PCK2	Phosphoenolpyruvate carboxykinase 2, mitochondrial. (645 aa)
	ENSCANP00000002557	Uncharacterized protein. (535 aa)
	ACSL5	Acyl-CoA synthetase long chain family member 5. (723 aa)
	POMC	Proopiomelanocortin. (251 aa)
	LEP	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
	CPT1C	Carnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (803 aa)
	PRKAG2	Protein kinase AMP-activated non-catalytic subunit gamma 2. (544 aa)
	TRAF2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
	SLC2A3	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (496 aa)
	LOC105519332	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (535 aa)
	SLC2A1	Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (486 aa)
	PRKAG1	Protein kinase AMP-activated non-catalytic subunit gamma 1. (344 aa)
	IKBKG	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (369 aa)
	CPT1A	Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
	ENSCANP00000036145	Uncharacterized protein. (268 aa)
	ACSBG2	Acyl-CoA synthetase bubblegum family member 2. (665 aa)
	TNFRSF1A	TNF receptor superfamily member 1A. (455 aa)
	ACSL4	Acyl-CoA synthetase long chain family member 4. (711 aa)
	ENSCANP00000034934	SH2 domain-containing protein. (183 aa)
	IRS4	Insulin receptor substrate 4. (1257 aa)
	JAK2	Tyrosine-protein kinase. (1139 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	ACSL1	Acyl-CoA synthetase long chain family member 1. (698 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (548 aa)
	ACSBG1	Acyl-CoA synthetase bubblegum family member 1. (723 aa)
	G6PC2	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
	RXRB	Retinoid X receptor beta. (539 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	SLC2A4	Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
	TNFRSF1B	TNF receptor superfamily member 1B. (445 aa)
	PRKAA2	Non-specific serine/threonine protein kinase. (545 aa)
	STK11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (244 aa)
	ENSCANP00000025796	Uncharacterized protein. (269 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (448 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACACB	ACSL3	ENSCANP00000007442	ENSCANP00000017996	Acetyl-CoA carboxylase beta.	Acyl-CoA synthetase long chain family member 3.	0.473
ACACB	ACSL4	ENSCANP00000007442	ENSCANP00000035732	Acetyl-CoA carboxylase beta.	Acyl-CoA synthetase long chain family member 4.	0.473
ACACB	CPT1A	ENSCANP00000007442	ENSCANP00000036344	Acetyl-CoA carboxylase beta.	Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family.	0.908
ACACB	CPT1B	ENSCANP00000007442	ENSCANP00000008966	Acetyl-CoA carboxylase beta.	Carnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family.	0.858
ACACB	CPT1C	ENSCANP00000007442	ENSCANP00000000733	Acetyl-CoA carboxylase beta.	Carnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family.	0.853
ACACB	PCK1	ENSCANP00000007442	ENSCANP00000017402	Acetyl-CoA carboxylase beta.	Phosphoenolpyruvate carboxykinase 1.	0.528
ACACB	PCK2	ENSCANP00000007442	ENSCANP00000002572	Acetyl-CoA carboxylase beta.	Phosphoenolpyruvate carboxykinase 2, mitochondrial.	0.535
ACACB	PRKAA1	ENSCANP00000007442	ENSCANP00000011436	Acetyl-CoA carboxylase beta.	Non-specific serine/threonine protein kinase.	0.860
ACACB	PRKAA2	ENSCANP00000007442	ENSCANP00000027072	Acetyl-CoA carboxylase beta.	Non-specific serine/threonine protein kinase.	0.860
ACACB	PRKAB1	ENSCANP00000007442	ENSCANP00000022776	Acetyl-CoA carboxylase beta.	Protein kinase AMP-activated non-catalytic subunit beta 1.	0.846
ACACB	PRKAB2	ENSCANP00000007442	ENSCANP00000009447	Acetyl-CoA carboxylase beta.	Protein kinase AMP-activated non-catalytic subunit beta 2.	0.859
ACACB	PRKAG1	ENSCANP00000007442	ENSCANP00000037195	Acetyl-CoA carboxylase beta.	Protein kinase AMP-activated non-catalytic subunit gamma 1.	0.833
ACACB	PRKAG2	ENSCANP00000007442	ENSCANP00000000191	Acetyl-CoA carboxylase beta.	Protein kinase AMP-activated non-catalytic subunit gamma 2.	0.835
ACACB	PRKAG3	ENSCANP00000007442	ENSCANP00000021050	Acetyl-CoA carboxylase beta.	Protein kinase AMP-activated non-catalytic subunit gamma 3.	0.833
ACSBG1	ACSBG2	ENSCANP00000030276	ENSCANP00000035961	Acyl-CoA synthetase bubblegum family member 1.	Acyl-CoA synthetase bubblegum family member 2.	0.823
ACSBG1	ACSL1	ENSCANP00000030276	ENSCANP00000033507	Acyl-CoA synthetase bubblegum family member 1.	Acyl-CoA synthetase long chain family member 1.	0.843
ACSBG1	ACSL3	ENSCANP00000030276	ENSCANP00000017996	Acyl-CoA synthetase bubblegum family member 1.	Acyl-CoA synthetase long chain family member 3.	0.853
ACSBG1	ACSL4	ENSCANP00000030276	ENSCANP00000035732	Acyl-CoA synthetase bubblegum family member 1.	Acyl-CoA synthetase long chain family member 4.	0.853
ACSBG1	ACSL5	ENSCANP00000030276	ENSCANP00000002264	Acyl-CoA synthetase bubblegum family member 1.	Acyl-CoA synthetase long chain family member 5.	0.844
ACSBG1	ACSL6	ENSCANP00000030276	ENSCANP00000009625	Acyl-CoA synthetase bubblegum family member 1.	AMP-binding domain-containing protein.	0.845