71 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PPP3CB	Serine/threonine-protein phosphatase. (524 aa)
	ORAI1	ORAI calcium release-activated calcium modulator 1. (238 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (499 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
	ENSCANP00000037159	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (113 aa)
	PRKG2	cGMP-dependent protein kinase. (762 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa)
	AGTR1	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
	GUCY1A1	Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
	PVALEF	Parvalbumin like EF-hand containing. (133 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2134 aa)
	LOC105506399	Uncharacterized protein. (246 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2697 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	LOC105521777	Uncharacterized protein. (317 aa)
	ENSCANP00000028447	Uncharacterized protein; Belongs to the calmodulin family. (173 aa)
	REN	Renin; Belongs to the peptidase A1 family. (406 aa)
	CALML4	Calmodulin like 4. (192 aa)
	NPPA	Natriuretic peptide A. (153 aa)
	PDE1B	Phosphodiesterase. (536 aa)
	CLCA4	Chloride channel accessory 4. (921 aa)
	CALM2	Calmodulin 2. (149 aa)
	EDN2	Endothelin 2. (178 aa)
	PDE1C	PDEase domain-containing protein. (387 aa)
	CLCA1	Chloride channel accessory 1. (913 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1121 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
	GNAI1	G protein subunit alpha i1. (354 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	GNAS	GNAS complex locus. (913 aa)
	PPP3R2	Protein phosphatase 3 regulatory subunit B, beta. (174 aa)
	EDN3	Endothelin 3. (230 aa)
	PTGER4	Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
	KCNMA1	Potassium calcium-activated channel subfamily M alpha 1. (1280 aa)
	PPP3R1	Uncharacterized protein. (189 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (345 aa)
	CTSB	Cathepsin B; Belongs to the peptidase C1 family. (339 aa)
	ADORA1	Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
	CACNA1F	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1971 aa)
	CALM3	Calmodulin 3. (149 aa)
	CALML6	Calmodulin like 6. (181 aa)
	PDE3B	Phosphodiesterase. (1113 aa)
	NPR1	Guanylate cyclase. (958 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (485 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	PDE1A	Phosphodiesterase. (544 aa)
	GUCY1A2	Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (691 aa)
	GNAI2	G protein subunit alpha i2. (355 aa)
	GNAI3	G protein subunit alpha i3. (301 aa)
	ACE	Angiotensin-converting enzyme. (1223 aa)
	CACNA1S	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
	ENSCANP00000009406	Uncharacterized protein; Belongs to the calmodulin family. (163 aa)
	ENSCANP00000009135	CLCA domain-containing protein. (336 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	GNAQ	G protein subunit alpha q. (313 aa)
	PTGER2	Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	ADRB2	Adrenoceptor beta 2. (415 aa)
	CALML3	Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (149 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
	PDE3A	Phosphodiesterase. (1141 aa)
	GUCY1B1	Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (642 aa)
	ADRB3	G_PROTEIN_RECEP_F1_2 domain-containing protein. (418 aa)
	ADCYAP1	Adenylate cyclase activating polypeptide 1. (176 aa)
	KCNJ2	Potassium voltage-gated channel subfamily J member 2. (427 aa)
	EDN1	Endothelin 1. (211 aa)
	CACNA1D	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
	CLCA2	Chloride channel accessory 2. (943 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE	AGT	ENSCANP00000011988	ENSCANP00000013314	Angiotensin-converting enzyme.	Angiotensinogen; Belongs to the serpin family.	0.942
ACE	AGTR1	ENSCANP00000011988	ENSCANP00000036402	Angiotensin-converting enzyme.	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	0.661
ACE	CALML3	ENSCANP00000011988	ENSCANP00000003591	Angiotensin-converting enzyme.	Calmodulin like 3; Belongs to the calmodulin family.	0.407
ACE	CALML4	ENSCANP00000011988	ENSCANP00000027376	Angiotensin-converting enzyme.	Calmodulin like 4.	0.406
ACE	EDN1	ENSCANP00000011988	ENSCANP00000000830	Angiotensin-converting enzyme.	Endothelin 1.	0.422
ACE	NPPA	ENSCANP00000011988	ENSCANP00000027031	Angiotensin-converting enzyme.	Natriuretic peptide A.	0.485
ACE	REN	ENSCANP00000011988	ENSCANP00000028061	Angiotensin-converting enzyme.	Renin; Belongs to the peptidase A1 family.	0.722
ADCY5	ADCY6	ENSCANP00000023274	ENSCANP00000031064	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.859
ADCY5	CALM1	ENSCANP00000023274	ENSCANP00000002864	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 1; Belongs to the calmodulin family.	0.461
ADCY5	CALM2	ENSCANP00000023274	ENSCANP00000024800	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 2.	0.461
ADCY5	CALM3	ENSCANP00000023274	ENSCANP00000014797	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 3.	0.461
ADCY5	CALML3	ENSCANP00000023274	ENSCANP00000003591	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 3; Belongs to the calmodulin family.	0.838
ADCY5	CALML4	ENSCANP00000023274	ENSCANP00000027376	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 4.	0.847
ADCY5	CALML6	ENSCANP00000023274	ENSCANP00000014100	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 6.	0.711
ADCY5	ENSCANP00000009406	ENSCANP00000023274	ENSCANP00000009406	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the calmodulin family.	0.461
ADCY5	ENSCANP00000028447	ENSCANP00000023274	ENSCANP00000028447	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the calmodulin family.	0.461
ADCY5	GNAI1	ENSCANP00000023274	ENSCANP00000022697	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i1.	0.686
ADCY5	GNAI2	ENSCANP00000023274	ENSCANP00000012671	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i2.	0.843
ADCY5	GNAI3	ENSCANP00000023274	ENSCANP00000012552	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit alpha i3.	0.686
ADCY5	GNAS	ENSCANP00000023274	ENSCANP00000020637	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS complex locus.	0.948