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OVCH2 OVCH2 LOC105514569 LOC105514569 PRKCB PRKCB RAB11A RAB11A PTRHD1 PTRHD1 LOC105522975 LOC105522975 ENSCANP00000021474 ENSCANP00000021474 CCK CCK SLC9A1 SLC9A1 LOC105511217 LOC105511217 LOC105511214 LOC105511214 PLA2G2E PLA2G2E GNAS GNAS TPCN2 TPCN2 CFTR CFTR PRSS1 PRSS1 ENSCANP00000018803 ENSCANP00000018803 KCNMA1 KCNMA1 ATP2A3 ATP2A3 SCTR SCTR ATP2B2 ATP2B2 ADCY9 ADCY9 CPA6 CPA6 ENSCANP00000014775 ENSCANP00000014775 PLA2G3 PLA2G3 LOC105511210 LOC105511210 ATP1B1 ATP1B1 CELA2B CELA2B TRPC1 TRPC1 SLC12A2 SLC12A2 PNLIPRP2 PNLIPRP2 ATP1B4 ATP1B4 LOC105510238 LOC105510238 CEL CEL CELA1 CELA1 PLA2G2F PLA2G2F PRKCG PRKCG ADCY2 ADCY2 RAB27A RAB27A RHOC RHOC ENSCANP00000009135 ENSCANP00000009135 ATP1A3 ATP1A3 CPA4 CPA4 PLA2G12A PLA2G12A ATP2B3 ATP2B3 ATP1A1 ATP1A1 RHOA RHOA PLA2G2D PLA2G2D ATP2B1 ATP2B1 PNLIPRP1 PNLIPRP1 GNAQ GNAQ CCKAR CCKAR BST1 BST1 PRSS37 PRSS37 CHRM3 CHRM3 CPA2 CPA2 CD38 CD38 ATP2A1 ATP2A1 RYR2 RYR2 LOC105522642 LOC105522642 SLC26A3 SLC26A3 PLCB2 PLCB2 PRKCA PRKCA PLA2G1B PLA2G1B ATP1B2 ATP1B2 LOC105505982 LOC105505982 RAB27B RAB27B SLC4A2 SLC4A2 ENSCANP00000000172 ENSCANP00000000172 CLCA2 CLCA2 ADCY4 ADCY4 LOC105510267 LOC105510267 ITPR1 ITPR1 LOC105521777 LOC105521777 CPA1 CPA1 ADCY7 ADCY7 ATP2B4 ATP2B4 CPA3 CPA3 ADCY8 ADCY8 PNLIP PNLIP ADCY3 ADCY3 PLCB3 PLCB3 PLA2G12B PLA2G12B PLA2G2C PLA2G2C RAB8A RAB8A FXYD2 FXYD2 AMY2B AMY2B ADCY1 ADCY1 KCNQ1 KCNQ1 ITPR2 ITPR2 PLCB1 PLCB1 SLC4A4 SLC4A4 CTRL CTRL RAP1B RAP1B PLCB4 PLCB4 ENSCANP00000034207 ENSCANP00000034207 RAB11B RAB11B OVCH1 OVCH1 ATP2A2 ATP2A2 LOC105506399 LOC105506399 CPB2 CPB2 CPB1 CPB1 ADCY6 ADCY6 LOC105511218 LOC105511218 RAB3D RAB3D CLCA4 CLCA4 PRSS2 PRSS2 ATP1A4 ATP1A4 PLA2G2A PLA2G2A RAP1A RAP1A LOC105522976 LOC105522976 CLCA1 CLCA1 ADCY5 ADCY5 ITPR3 ITPR3 PLA2G5 PLA2G5
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
OVCH2Ovochymase 2 (gene/pseudogene); Belongs to the peptidase S1 family. (565 aa)
LOC105514569Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (285 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
RAB11ARAB11A, member RAS oncogene family. (216 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
LOC105522975Cation_ATPase_C domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (409 aa)
ENSCANP00000021474Uncharacterized protein. (136 aa)
CCKCholecystokinin. (115 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
LOC105511217Serine protease 1; Belongs to the peptidase S1 family. (247 aa)
LOC105511214Peptidase S1 domain-containing protein. (267 aa)
PLA2G2EPhospholipase A(2). (142 aa)
GNASGNAS complex locus. (913 aa)
TPCN2Two pore segment channel 2. (728 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
PRSS1Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (256 aa)
ENSCANP00000018803Uncharacterized protein. (85 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1280 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1060 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (408 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1270 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
CPA6Carboxypeptidase A6. (437 aa)
ENSCANP00000014775Uncharacterized protein. (130 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
LOC105511210Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
CELA2BChymotrypsin like elastase 2B. (234 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
SLC12A2Solute carrier family 12 member 2. (1102 aa)
PNLIPRP2Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (469 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (357 aa)
LOC105510238Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (269 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (650 aa)
CELA1Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (257 aa)
PLA2G2FPhospholipase A(2). (199 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1014 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
RHOCRas homolog family member C. (193 aa)
ENSCANP00000009135CLCA domain-containing protein. (336 aa)
ATP1A3Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1263 aa)
CPA4Carboxypeptidase A4. (421 aa)
PLA2G12APhospholipase A2 group XIIA. (187 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1028 aa)
RHOARas homolog family member A. (193 aa)
PLA2G2DPhospholipase A(2). (145 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
PNLIPRP1Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (469 aa)
GNAQG protein subunit alpha q. (313 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
BST1Bone marrow stromal cell antigen 1. (315 aa)
PRSS37Serine protease 37. (234 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
CPA2Carboxypeptidase A2. (419 aa)
CD38CD38 molecule. (301 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1027 aa)
RYR2Ryanodine receptor 2. (4920 aa)
LOC105522642Sodium/potassium-transporting ATPase subunit alpha. (641 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (761 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
PLA2G1BPhospholipase A(2). (147 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
LOC105505982Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (270 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
SLC4A2Anion exchange protein. (1240 aa)
ENSCANP00000000172Peptidase S1 domain-containing protein. (176 aa)
CLCA2Chloride channel accessory 2. (943 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
LOC105510267Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (262 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2697 aa)
LOC105521777Uncharacterized protein. (317 aa)
CPA1Carboxypeptidase A1. (419 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1083 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
CPA3Carboxypeptidase A3. (417 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
PNLIPTriacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (468 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1142 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1227 aa)
PLA2G12BPhospholipase A2 group XIIB. (195 aa)
PLA2G2CPhospholipase A(2). (150 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
AMY2BAlpha-amylase. (511 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (976 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (612 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa)
SLC4A4Anion exchange protein. (1100 aa)
CTRLChymotrypsin like; Belongs to the peptidase S1 family. (263 aa)
RAP1BUncharacterized protein. (184 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
ENSCANP00000034207Uncharacterized protein. (89 aa)
RAB11BRAB11B, member RAS oncogene family. (218 aa)
OVCH1Ovochymase 1; Belongs to the peptidase S1 family. (1052 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (999 aa)
LOC105506399Uncharacterized protein. (246 aa)
CPB2Carboxypeptidase B2. (423 aa)
CPB1Carboxypeptidase B1. (417 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
LOC105511218Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (261 aa)
RAB3DRAB3D, member RAS oncogene family. (219 aa)
CLCA4Chloride channel accessory 4. (921 aa)
PRSS2Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (264 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
PLA2G2APhospholipase A(2). (144 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
LOC105522976Cation_ATPase_C domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (398 aa)
CLCA1Chloride channel accessory 1. (913 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1121 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
PLA2G5Phospholipase A(2). (138 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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