74 items (Colobus angolensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
	CACNA1D	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
	CAMK4	Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (448 aa)
	SLC18A2	Solute carrier family 18 member A2. (517 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (499 aa)
	CREB3L3	cAMP responsive element binding protein 3 like 3. (415 aa)
	GRIN2B	Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
	CREB3	cAMP responsive element binding protein 3. (372 aa)
	FOSB	FosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
	CAMK2G	Calcium/calmodulin dependent protein kinase II gamma. (552 aa)
	CREB3L2	cAMP responsive element binding protein 3 like 2. (461 aa)
	PVALEF	Parvalbumin like EF-hand containing. (133 aa)
	ATF6B	Activating transcription factor 6 beta. (690 aa)
	GRIA4	Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
	PPP1R1B	Protein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2134 aa)
	LOC105506399	Uncharacterized protein. (246 aa)
	JUN	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
	SLC18A1	Solute carrier family 18 member A1. (525 aa)
	ATF4	Activating transcription factor 4. (351 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (476 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	CREB3L1	cAMP responsive element binding protein 3 like 1. (519 aa)
	ENSCANP00000028447	Uncharacterized protein; Belongs to the calmodulin family. (173 aa)
	CALML4	Calmodulin like 4. (192 aa)
	CREB3L4	cAMP responsive element binding protein 3 like 4. (427 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
	GRIN2C	Glutamate ionotropic receptor NMDA type subunit 2C; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1005 aa)
	CALM2	Calmodulin 2. (149 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
	ADCY5	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1121 aa)
	TH	Tyrosine hydroxylase. (529 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
	ARSI	Arylsulfatase family member I. (569 aa)
	GNAS	GNAS complex locus. (913 aa)
	PPP3R2	Protein phosphatase 3 regulatory subunit B, beta. (174 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
	GRIN1	Glutamate ionotropic receptor NMDA type subunit 1. (834 aa)
	PPP3R1	Uncharacterized protein. (189 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (345 aa)
	CAMK2B	Calcium/calmodulin dependent protein kinase II beta. (666 aa)
	CAMK2D	Calcium/calmodulin dependent protein kinase II delta. (533 aa)
	STX1A	Syntaxin 1A; Belongs to the syntaxin family. (289 aa)
	CALM3	Calmodulin 3. (149 aa)
	CALML6	Calmodulin like 6. (181 aa)
	CAMK2A	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
	GRIA2	Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (322 aa)
	CREB5	Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa)
	LOC105516286	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (449 aa)
	MAOA	Amine oxidase. (527 aa)
	PDYN	Prodynorphin. (254 aa)
	DDC	Dopa decarboxylase. (480 aa)
	PRKCG	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
	ENSCANP00000009406	Uncharacterized protein; Belongs to the calmodulin family. (163 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa)
	SIRT1	Sirtuin 1. (600 aa)
	GRIA3	Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (524 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
	DRD1	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
	ARC	Activity regulated cytoskeleton associated protein. (396 aa)
	CALML3	Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
	MAOB	Amine oxidase. (520 aa)
	LOC105527037	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (459 aa)
	ENSCANP00000003071	SER_THR_PHOSPHATASE domain-containing protein. (146 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (149 aa)
	GRIA1	Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
	GRIN2D	Glutamate ionotropic receptor NMDA type subunit 2D. (674 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)

Your Current Organism:

Colobus angolensis

NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	CALM1	ENSCANP00000023274	ENSCANP00000002864	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 1; Belongs to the calmodulin family.	0.461
ADCY5	CALM2	ENSCANP00000023274	ENSCANP00000024800	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 2.	0.461
ADCY5	CALM3	ENSCANP00000023274	ENSCANP00000014797	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 3.	0.461
ADCY5	CALML3	ENSCANP00000023274	ENSCANP00000003591	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 3; Belongs to the calmodulin family.	0.838
ADCY5	CALML4	ENSCANP00000023274	ENSCANP00000027376	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 4.	0.847
ADCY5	CALML6	ENSCANP00000023274	ENSCANP00000014100	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 6.	0.711
ADCY5	CAMK2A	ENSCANP00000023274	ENSCANP00000014071	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily.	0.823
ADCY5	CAMK2B	ENSCANP00000023274	ENSCANP00000017713	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II beta.	0.818
ADCY5	CAMK2D	ENSCANP00000023274	ENSCANP00000017711	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II delta.	0.818
ADCY5	CAMK2G	ENSCANP00000023274	ENSCANP00000034657	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase II gamma.	0.595
ADCY5	CAMK4	ENSCANP00000023274	ENSCANP00000000637	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily.	0.820
ADCY5	ENSCANP00000009406	ENSCANP00000023274	ENSCANP00000009406	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the calmodulin family.	0.461
ADCY5	ENSCANP00000028447	ENSCANP00000023274	ENSCANP00000028447	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the calmodulin family.	0.461
ADCY5	GNAS	ENSCANP00000023274	ENSCANP00000020637	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS complex locus.	0.948
ADCY5	LOC105506399	ENSCANP00000023274	ENSCANP00000032034	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.818
ADCY5	PRKACA	ENSCANP00000023274	ENSCANP00000018127	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.896
ADCY5	PRKACB	ENSCANP00000023274	ENSCANP00000007296	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.918
ADCY5	PRKCA	ENSCANP00000023274	ENSCANP00000002673	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.867
ADCY5	PRKCB	ENSCANP00000023274	ENSCANP00000022368	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.842
ADCY5	PRKCG	ENSCANP00000023274	ENSCANP00000009767	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.829