STRINGSTRING
ENSCANP00000016286 ENSCANP00000016286 LOC105514240 LOC105514240 JAK1 JAK1 LOC105502761 LOC105502761 PIK3R5 PIK3R5 MAPK3 MAPK3 LOC105500830 LOC105500830 AKT1 AKT1 IFNG IFNG HLA-DRA HLA-DRA MAPK12 MAPK12 ITGA6 ITGA6 ITGB1 ITGB1 GNAI2 GNAI2 LAMA3 LAMA3 GNAI3 GNAI3 CASP8 CASP8 LAMA5 LAMA5 IKBKB IKBKB MAPK9 MAPK9 LAMA1 LAMA1 TGFB1 TGFB1 CASP9 CASP9 CIITA CIITA LDLR LDLR LOC105501361 LOC105501361 NFKBIA NFKBIA LOC105521523 LOC105521523 MAP2K6 MAP2K6 ENSCANP00000006223 ENSCANP00000006223 ENSCANP00000005565 ENSCANP00000005565 CHUK CHUK MAP3K7 MAP3K7 BAD BAD BCL2 BCL2 BIRC7 BIRC7 BIRC2 BIRC2 CD40 CD40 LAMB2 LAMB2 TLR2 TLR2 LOC105501360 LOC105501360 ENSCANP00000003898 ENSCANP00000003898 CCR5 CCR5 LOC105516629 LOC105516629 ENSCANP00000002453 ENSCANP00000002453 HSPA6 HSPA6 MAPK11 MAPK11 PIK3CG PIK3CG LOC105523208 LOC105523208 PIK3R6 PIK3R6 HSPA8 HSPA8 BCL2L1 BCL2L1 LOC105521896 LOC105521896 ENSCANP00000000466 ENSCANP00000000466 CASP3 CASP3 ENSCANP00000040251 ENSCANP00000040251 MAPK14 MAPK14 XIAP XIAP ENSCANP00000038640 ENSCANP00000038640 PPIF PPIF IFNGR2 IFNGR2 PPP1R14B PPP1R14B HLA-DOA HLA-DOA IL12A IL12A HSPA2 HSPA2 IKBKG IKBKG IL10 IL10 TNFRSF1A TNFRSF1A IL10RB IL10RB HLA-DMA HLA-DMA NOS2 NOS2 CD40LG CD40LG JAK2 JAK2 IL12B IL12B ENSCANP00000033724 ENSCANP00000033724 MAPK13 MAPK13 RELA RELA CYCS CYCS TGFB3 TGFB3 LOC105501359 LOC105501359 MYD88 MYD88 HLA-DOB HLA-DOB ENSCANP00000030335 ENSCANP00000030335 LAMB1 LAMB1 IRAK4 IRAK4 HSPA1L HSPA1L LAMC2 LAMC2 TLR4 TLR4 LAMB4 LAMB4 AKT3 AKT3 LOC105513798 LOC105513798 STAT1 STAT1 MAPK1 MAPK1 TAB2 TAB2 IFNGR1 IFNGR1 BIRC3 BIRC3 NFKB1 NFKB1 PDPK1 PDPK1 IL10RA IL10RA LOC105513786 LOC105513786 GNAI1 GNAI1 STAT3 STAT3 LAMA4 LAMA4 TNF TNF AKT2 AKT2 HLA-DQA1 HLA-DQA1 LOC105503927 LOC105503927 LAMA2 LAMA2 HLA-DRB5 HLA-DRB5 ALOX5 ALOX5 ENSCANP00000020790 ENSCANP00000020790 TGFB2 TGFB2 MAPK8 MAPK8 LOC105513801 LOC105513801 LAMC3 LAMC3 NFKBIB NFKBIB TYK2 TYK2 LY96 LY96 GNAO1 GNAO1 IRAK1 IRAK1 C7orf31 C7orf31 MAPK10 MAPK10 HLA-DQB1 HLA-DQB1 TRAF6 TRAF6 TAB1 TAB1 LAMB3 LAMB3 MAP2K3 MAP2K3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ENSCANP00000016286Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (86 aa)
LOC105514240Ig-like domain-containing protein. (256 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
LOC105502761Ig-like domain-containing protein. (283 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (879 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
LOC105500830Uncharacterized protein; Belongs to the heat shock protein 70 family. (608 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1070 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
GNAI2G protein subunit alpha i2. (355 aa)
LAMA3Laminin subunit alpha 3. (3235 aa)
GNAI3G protein subunit alpha i3. (301 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (538 aa)
LAMA5Laminin subunit alpha 5. (3457 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
MAPK9Mitogen-activated protein kinase. (399 aa)
LAMA1Laminin subunit alpha 1. (3054 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (416 aa)
CIITAClass II major histocompatibility complex transactivator. (1131 aa)
LDLRLow density lipoprotein receptor. (777 aa)
LOC105501361Ig-like domain-containing protein. (296 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
LOC105521523Uncharacterized protein; Belongs to the heat shock protein 70 family. (599 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ENSCANP00000006223Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSCANP00000005565Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (101 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
BADBCL2 associated agonist of cell death. (167 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
BIRC7Baculoviral IAP repeat containing 7. (298 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
CD40CD40 molecule. (278 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
TLR2Toll-like receptor. (784 aa)
LOC105501360Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
ENSCANP00000003898Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CCR5C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (352 aa)
LOC105516629Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
ENSCANP00000002453Uncharacterized protein; Belongs to the heat shock protein 70 family. (529 aa)
HSPA6Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (576 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
LOC105523208Uncharacterized protein. (380 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (709 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
BCL2L1BCL2 like 1. (233 aa)
LOC105521896Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSCANP00000000466Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CASP3Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa)
ENSCANP00000040251Uncharacterized protein; Belongs to the peptidase C14A family. (243 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
ENSCANP00000038640Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (96 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (159 aa)
IFNGR2Interferon gamma receptor 2. (231 aa)
PPP1R14BProtein phosphatase 1 regulatory inhibitor subunit 14B. (132 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (602 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (369 aa)
IL10Interleukin 10. (178 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
IL10RBInterleukin 10 receptor subunit beta. (325 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1181 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
JAK2Tyrosine-protein kinase. (1139 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
ENSCANP00000033724Uncharacterized protein. (794 aa)
MAPK13Mitogen-activated protein kinase. (491 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
CYCSCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
LOC105501359Ig-like domain-containing protein. (281 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa)
HLA-DOBMajor histocompatibility complex, class II, DO beta. (273 aa)
ENSCANP00000030335Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (97 aa)
LAMB1Laminin subunit beta 1. (1796 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (438 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
LAMC2Laminin subunit gamma 2. (1193 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
LAMB4Laminin subunit beta 4. (1684 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC105513798Ig-like domain-containing protein. (263 aa)
STAT1Signal transducer and activator of transcription. (765 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
IFNGR1Interferon gamma receptor 1. (489 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
NFKB1Nuclear factor kappa B subunit 1. (970 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (406 aa)
IL10RAInterleukin 10 receptor subunit alpha. (578 aa)
LOC105513786Ig-like domain-containing protein. (266 aa)
GNAI1G protein subunit alpha i1. (354 aa)
STAT3Signal transducer and activator of transcription. (795 aa)
LAMA4Laminin subunit alpha 4. (1816 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa)
HLA-DQA1Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (256 aa)
LOC105503927Uncharacterized protein; Belongs to the heat shock protein 70 family. (592 aa)
LAMA2Laminin subunit alpha 2. (3066 aa)
HLA-DRB5Major histocompatibility complex, class II, DR beta 5. (266 aa)
ALOX5Arachidonate 5-lipoxygenase. (508 aa)
ENSCANP00000020790Uncharacterized protein. (84 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
LOC105513801Ig-like domain-containing protein. (279 aa)
LAMC3Laminin subunit gamma 3. (1410 aa)
NFKBIBNFKB inhibitor beta. (321 aa)
TYK2Tyrosine-protein kinase. (1187 aa)
LY96Lymphocyte antigen 96. (160 aa)
GNAO1G protein subunit alpha o1. (354 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (648 aa)
C7orf31Chromosome 7 open reading frame 31. (590 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (269 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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