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| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | ENSCANP00000020790 | Uncharacterized protein. (84 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | TYK2 | Tyrosine-protein kinase. (1187 aa) |
| | ENSCANP00000019829 | Uncharacterized protein. (98 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | STAT4 | Signal transducer and activator of transcription. (748 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (648 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | C7orf31 | Chromosome 7 open reading frame 31. (590 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (550 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (918 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | HSPG2 | Heparan sulfate proteoglycan 2. (4290 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | CASP12 | Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (336 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | DDX58 | DExD/H-box helicase 58. (925 aa) |
| | IFIH1 | Interferon induced with helicase C domain 1. (1025 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | ENSCANP00000016286 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (86 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (362 aa) |
| | EGR3 | Early growth response 3. (387 aa) |
| | JAK1 | Tyrosine-protein kinase. (1159 aa) |
| | DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (721 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | LOC105504658 | Uncharacterized protein. (571 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa) |
| | ENSCANP00000014581 | 14_3_3 domain-containing protein. (97 aa) |
| | EP300 | E1A binding protein p300. (2409 aa) |
| | MAVS | Uncharacterized protein. (401 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (468 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (325 aa) |
| | ENSCANP00000013595 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (124 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (200 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (369 aa) |
| | STAT5B | Signal transducer and activator of transcription. (756 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) |
| | STAT5A | Signal transducer and activator of transcription. (789 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) |
| | ENSCANP00000011903 | 14_3_3 domain-containing protein. (107 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (399 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (815 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1067 aa) |
| | ENSCANP00000009565 | Uncharacterized protein. (651 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (336 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (416 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (923 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) |
| | YWHAQ | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (540 aa) |
| | ELK1 | ETS domain-containing protein. (428 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | ENSCANP00000006830 | Protein kinase domain-containing protein. (373 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1147 aa) |
| | ENSCANP00000006223 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ENSCANP00000005565 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (101 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | LOC105509448 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (245 aa) |
| | TIRAP | TIR domain containing adaptor protein. (220 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | TLR2 | Toll-like receptor. (784 aa) |
| | ENSCANP00000003898 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC105507704 | ETS domain-containing protein. (403 aa) |
| | ENSCANP00000002796 | Uncharacterized protein. (232 aa) |
| | SLC10A1 | Solute carrier family 10 member 1. (349 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa) |
| | LOC105516629 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (409 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (468 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (306 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | TBK1 | TANK binding kinase 1. (713 aa) |
| | STAT2 | Signal transducer and activator of transcription. (708 aa) |
| | LOC105503436 | Uncharacterized protein. (198 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | LOC105521896 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ENSCANP00000000466 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CASP3 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) |
| | JAK3 | Tyrosine-protein kinase. (1124 aa) |
| | FAS | Fas cell surface death receptor. (331 aa) |
| | E2F1 | E2F transcription factor 1. (436 aa) |
| | ENSCANP00000030373 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (226 aa) |
| | ENSCANP00000030335 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (97 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (438 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | IRF7 | Interferon regulatory factor 7. (503 aa) |
| | TICAM2 | Toll like receptor adaptor molecule 2. (235 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (519 aa) |
| | CREBBP | CREB binding protein. (2117 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (636 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (198 aa) |
| | GRB2 | Uncharacterized protein. (156 aa) |
| | ENSCANP00000040251 | Uncharacterized protein; Belongs to the peptidase C14A family. (243 aa) |
| | ENSCANP00000040247 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa) |
| | SRC | Tyrosine-protein kinase. (458 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (253 aa) |
| | ENSCANP00000039354 | Protein kinase domain-containing protein. (353 aa) |
| | ENSCANP00000038640 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (96 aa) |
| | E2F3 | E2F transcription factor 3. (381 aa) |
| | IL6 | Interleukin 6. (214 aa) |
| | TMED7 | Transmembrane p24 trafficking protein 7. (224 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (415 aa) |
| | PPP1R14B | Protein phosphatase 1 regulatory inhibitor subunit 14B. (132 aa) |
| | PIK3CD | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1071 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (369 aa) |
| | BIRC5 | Baculoviral IAP repeat containing 5. (147 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (747 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (372 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | ENSCANP00000035277 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (235 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (461 aa) |
| | JAK2 | Tyrosine-protein kinase. (1139 aa) |
| | ATF6B | Activating transcription factor 6 beta. (690 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (491 aa) |
| | MMP9 | Matrix metallopeptidase 9. (707 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (427 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1310 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) |
| | ENSCANP00000032589 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (251 aa) |
| | PIK3R2 | Uncharacterized protein. (601 aa) |
| | CYCS | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | EGR2 | Early growth response 2. (476 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | TICAM1 | Toll like receptor adaptor molecule 1. (517 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | STAT1 | Signal transducer and activator of transcription. (765 aa) |
| | CREB3L4 | cAMP responsive element binding protein 3 like 4. (427 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (343 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (484 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1356 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | BID | BH3 interacting domain death agonist. (255 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (970 aa) |
| | IRF3 | Interferon regulatory factor 3. (426 aa) |
| | CSDE1 | Uncharacterized protein. (844 aa) |
| | STAT3 | Signal transducer and activator of transcription. (795 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (373 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (587 aa) |
| | ENSCANP00000022034 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (214 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | AKT2 | AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa) |
