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| | LOC105508804 | Uncharacterized protein. (457 aa) |
| | GRB2 | Uncharacterized protein. (156 aa) |
| | BMF | Bcl2 modifying factor. (184 aa) |
| | ENSCANP00000040251 | Uncharacterized protein; Belongs to the peptidase C14A family. (243 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa) |
| | CDC25A | Cell division cycle 25A. (501 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (802 aa) |
| | ENSCANP00000039354 | Protein kinase domain-containing protein. (353 aa) |
| | PIM1 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (306 aa) |
| | TPM1 | Uncharacterized protein; Belongs to the tropomyosin family. (319 aa) |
| | E2F3 | E2F transcription factor 3. (381 aa) |
| | RDX | Radixin. (604 aa) |
| | CCNG1 | Cyclin G1; Belongs to the cyclin family. (295 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (468 aa) |
| | SERPINB5 | Serpin family B member 5; Belongs to the serpin family. (327 aa) |
| | ADAM15 | ADAM metallopeptidase domain 15. (844 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (654 aa) |
| | PIK3CD | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1071 aa) |
| | GLS2 | Glutaminase 2. (603 aa) |
| | ST14 | Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (849 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | GLS | Glutaminase. (669 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | TNN | Tenascin N. (1299 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (808 aa) |
| | MMP9 | Matrix metallopeptidase 9. (707 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | ENSCANP00000033343 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (198 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1310 aa) |
| | LOC105520435 | Uncharacterized protein. (403 aa) |
| | ABCC1 | ATP binding cassette subfamily C member 1. (1330 aa) |
| | ENSCANP00000032612 | SWIB domain-containing protein. (72 aa) |
| | TNC | Tenascin C. (2201 aa) |
| | PIK3R2 | Uncharacterized protein. (601 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | BMPR2 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (553 aa) |
| | CEP152 | Centrosomal protein 152. (1709 aa) |
| | TPTE2 | Uncharacterized protein. (522 aa) |
| | CREBBP | CREB binding protein. (2117 aa) |
| | E2F1 | E2F transcription factor 1. (436 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | CD44 | CD44 molecule (Indian blood group). (742 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (476 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (412 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | DNMT3A | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa) |
| | TRIM71 | Tripartite motif containing 71. (654 aa) |
| | NOTCH1 | Notch receptor 1. (2559 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (343 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (970 aa) |
| | KIF23 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (960 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (784 aa) |
| | SHC1 | SHC adaptor protein 1. (584 aa) |
| | CSDE1 | Uncharacterized protein. (844 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1404 aa) |
| | HNRNPK | Heterogeneous nuclear ribonucleoprotein K. (464 aa) |
| | STAT3 | Signal transducer and activator of transcription. (795 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa) |
| | TNXB | Uncharacterized protein. (3943 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | THBS1 | Thrombospondin 1. (1173 aa) |
| | TIMP3 | TIMP metallopeptidase inhibitor 3. (211 aa) |
| | NOTCH4 | Notch receptor 4. (2001 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | HOXD10 | Homeobox D10. (340 aa) |
| | TNR | Tenascin R. (1358 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | EYS | Eyes shut homolog. (3140 aa) |
| | GPSM3 | G protein signaling modulator 3. (160 aa) |
| | ENSCANP00000019829 | Uncharacterized protein. (98 aa) |
| | EZR | Ezrin. (587 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (232 aa) |
| | EFNA3 | Ephrin A3; Belongs to the ephrin family. (236 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (1681 aa) |
| | NOTCH3 | Notch receptor 3. (2021 aa) |
| | DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1646 aa) |
| | ZFPM2 | Zinc finger protein, FOG family member 2. (1137 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | LOC105523325 | Uncharacterized protein. (284 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | IGF2BP1 | Insulin like growth factor 2 mRNA binding protein 1. (577 aa) |
| | CYP24A1 | Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (514 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1188 aa) |
| | EFNA2 | Ephrin A2; Belongs to the ephrin family. (227 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1775 aa) |
| | MDM4 | MDM4 regulator of p53. (340 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1090 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1049 aa) |
| | DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1920 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa) |
| | HMGA2 | High mobility group AT-hook 2. (147 aa) |
| | SLC7A1 | Solute carrier family 7 member 1. (629 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | LOC105504658 | Uncharacterized protein. (571 aa) |
| | STMN1 | Stathmin; Belongs to the stathmin family. (108 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (205 aa) |
| | EP300 | E1A binding protein p300. (2409 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1331 aa) |
| | MCL1 | MCL1 apoptosis regulator, BCL2 family member. (349 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (369 aa) |
| | MMP16 | Matrix metallopeptidase 16. (607 aa) |
| | HDAC5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1125 aa) |
| | ZEB2 | Zinc finger E-box binding homeobox 2. (1253 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1124 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa) |
| | LOC105516286 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (449 aa) |
| | PLAU | Plasminogen activator, urokinase. (431 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | RASSF1 | Ras association domain family member 1. (270 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa) |
| | RHOC | Ras homolog family member C. (193 aa) |
| | PDCD4 | Programmed cell death 4. (470 aa) |
| | FOXP1 | Forkhead box P1. (693 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | NOTCH2 | Notch receptor 2. (2471 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (597 aa) |
| | DNMT3B | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (853 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1259 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | SIRT1 | Sirtuin 1. (600 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1330 aa) |
| | APC | APC regulator of WNT signaling pathway. (2843 aa) |
| | EFNA4 | Ephrin A4; Belongs to the ephrin family. (201 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | LOC105527518 | RING-type domain-containing protein. (326 aa) |
| | CDC25B | Cell division cycle 25B. (580 aa) |
| | ENSCANP00000006130 | C2H2-type domain-containing protein. (254 aa) |
| | IRS1 | Insulin receptor substrate 1. (1243 aa) |
| | CDKN2A | Cyclin dependent kinase inhibitor 2A. (159 aa) |
| | PDGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (307 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa) |
| | RECK | Reversion inducing cysteine rich protein with kazal motifs. (971 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | SHC4 | SHC adaptor protein 4. (630 aa) |
| | CDCA5 | Cell division cycle associated 5. (252 aa) |
| | FSCN2 | Fascin actin-bundling protein 2, retinal. (427 aa) |
| | FSCN1 | Fascin. (493 aa) |
| | ENSCANP00000003781 | Uncharacterized protein. (378 aa) |
| | LOC105527037 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (459 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa) |
| | ENSCANP00000002629 | Uncharacterized protein. (87 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (409 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1257 aa) |
| | UBE2I | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (315 aa) |
| | CDC25C | Cell division cycle 25C. (475 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | CASP3 | Uncharacterized protein; Belongs to the peptidase C14A family. (277 aa) |
