STRINGSTRING
CSNK2B CSNK2B ENSCANP00000025796 ENSCANP00000025796 MAPK1 MAPK1 STAT1 STAT1 CD274 CD274 PTPN6 PTPN6 TICAM1 TICAM1 AKT3 AKT3 CD28 CD28 HIF1A HIF1A TLR4 TLR4 TICAM2 TICAM2 PPP3CA PPP3CA CD3D CD3D PIK3CB PIK3CB TLR9 TLR9 RASGRP1 RASGRP1 MYD88 MYD88 JUN JUN TPTE2 TPTE2 ERAS ERAS MAPK11 MAPK11 LTK LTK ENSCANP00000002557 ENSCANP00000002557 ENSCANP00000002629 ENSCANP00000002629 TLR2 TLR2 TRAV22 TRAV22 HRAS HRAS TIRAP TIRAP CHUK CHUK NFKBIE NFKBIE KRAS KRAS PPP3CB PPP3CB ALK ALK MAP2K6 MAP2K6 NFKBIA NFKBIA MAP3K3 MAP3K3 NFATC2 NFATC2 PRKCQ PRKCQ NFATC3 NFATC3 PTEN PTEN NFATC1 NFATC1 IKBKB IKBKB ENSCANP00000011220 ENSCANP00000011220 PLCG1 PLCG1 MAP2K2 MAP2K2 MAPK12 MAPK12 RPS6KB2 RPS6KB2 MAPK14 MAPK14 PPP3CC PPP3CC ENSCANP00000039354 ENSCANP00000039354 LAT LAT PDCD1 PDCD1 LCK LCK ZAP70 ZAP70 TMED7 TMED7 IFNGR2 IFNGR2 CD3E CD3E CD4 CD4 BATF2 BATF2 PIK3CD PIK3CD IKBKG IKBKG ENSCANP00000036145 ENSCANP00000036145 PIK3R3 PIK3R3 BATF3 BATF3 MAP2K1 MAP2K1 ENSCANP00000034934 ENSCANP00000034934 JAK2 JAK2 CD3G CD3G MAPK13 MAPK13 PTPN11 PTPN11 RELA RELA PIK3R2 PIK3R2 MAP2K3 MAP2K3 PIK3CA PIK3CA JAK1 JAK1 CD247 CD247 MAPK3 MAPK3 LOC105504658 LOC105504658 AKT1 AKT1 IFNG IFNG BATF BATF STAT3 STAT3 TRAC TRAC MTOR MTOR AKT2 AKT2 PIK3R1 PIK3R1 CSNK2A2 CSNK2A2 PPP3R2 PPP3R2 NFKBIB NFKBIB ENSCANP00000019829 ENSCANP00000019829 FOS FOS EGF EGF EML4 EML4 PPP3R1 PPP3R1 RAF1 RAF1 EGFR EGFR TRAF6 TRAF6 CSNK2A1 CSNK2A1 RPS6KB1 RPS6KB1 CSDE1 CSDE1 NFKB1 NFKB1 IFNGR1 IFNGR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSNK2BUncharacterized protein. (296 aa)
ENSCANP00000025796Uncharacterized protein. (269 aa)
MAPK1Mitogen-activated protein kinase. (343 aa)
STAT1Signal transducer and activator of transcription. (765 aa)
CD274CD274 molecule. (290 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (613 aa)
TICAM1Toll like receptor adaptor molecule 1. (517 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
CD28CD28 molecule. (220 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (827 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
TICAM2Toll like receptor adaptor molecule 2. (235 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
CD3DCD3d molecule. (171 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
TLR9TIR domain-containing protein. (1033 aa)
RASGRP1RAS guanyl releasing protein 1. (793 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
TPTE2Uncharacterized protein. (522 aa)
ERASES cell expressed Ras. (233 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
LTKTyrosine-protein kinase receptor. (803 aa)
ENSCANP00000002557Uncharacterized protein. (535 aa)
ENSCANP00000002629Uncharacterized protein. (87 aa)
TLR2Toll-like receptor. (784 aa)
TRAV22T cell receptor alpha variable 22. (147 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
TIRAPTIR domain containing adaptor protein. (220 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
NFKBIENFKB inhibitor epsilon. (487 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
ALKTyrosine-protein kinase receptor. (1388 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (657 aa)
NFATC2Nuclear factor of activated T cells 2. (923 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
NFATC3Nuclear factor of activated T cells 3. (1067 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
NFATC1Nuclear factor of activated T cells 1. (815 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
ENSCANP00000011220Uncharacterized protein. (277 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1278 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (369 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PPP3CCSerine/threonine-protein phosphatase. (499 aa)
ENSCANP00000039354Protein kinase domain-containing protein. (353 aa)
LATLinker for activation of T cells. (254 aa)
PDCD1Programmed cell death 1. (293 aa)
LCKTyrosine-protein kinase. (539 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
TMED7Transmembrane p24 trafficking protein 7. (224 aa)
IFNGR2Interferon gamma receptor 2. (231 aa)
CD3ECD3e molecule. (198 aa)
CD4CD4 molecule. (458 aa)
BATF2Basic leucine zipper ATF-like transcription factor 2. (273 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1071 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (369 aa)
ENSCANP00000036145Uncharacterized protein. (268 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
BATF3Basic leucine zipper ATF-like transcription factor 3. (131 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ENSCANP00000034934SH2 domain-containing protein. (183 aa)
JAK2Tyrosine-protein kinase. (1139 aa)
CD3GCD3g molecule. (181 aa)
MAPK13Mitogen-activated protein kinase. (491 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
PIK3R2Uncharacterized protein. (601 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
CD247CD247 molecule. (163 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
LOC105504658Uncharacterized protein. (571 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
STAT3Signal transducer and activator of transcription. (795 aa)
TRACT cell receptor alpha constant. (110 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (323 aa)
PPP3R2Protein phosphatase 3 regulatory subunit B, beta. (174 aa)
NFKBIBNFKB inhibitor beta. (321 aa)
ENSCANP00000019829Uncharacterized protein. (98 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
EML4EMAP like 4. (991 aa)
PPP3R1Uncharacterized protein. (189 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
EGFRReceptor protein-tyrosine kinase. (1188 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
CSDE1Uncharacterized protein. (844 aa)
NFKB1Nuclear factor kappa B subunit 1. (970 aa)
IFNGR1Interferon gamma receptor 1. (489 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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