STRINGSTRING
LOC105509062 LOC105509062 LOC105525270 LOC105525270 IL1A IL1A TXN2 TXN2 HSP90B1 HSP90B1 LOC105525271 LOC105525271 MGST2 MGST2 PVALEF PVALEF GSTT2B GSTT2B HSP90AB1 HSP90AB1 ACTG1 ACTG1 MAPK13 MAPK13 MMP9 MMP9 SDC4 SDC4 VCAM1 VCAM1 NPPC NPPC KDR KDR RELA RELA NCF1 NCF1 ENSCANP00000032715 ENSCANP00000032715 SQSTM1 SQSTM1 CTSL CTSL PIK3R2 PIK3R2 BMPR2 BMPR2 ARHGEF2 ARHGEF2 JUN JUN ICAM1 ICAM1 IL1B IL1B LOC105514391 LOC105514391 LOC105522998 LOC105522998 DUSP1 DUSP1 PIK3CB PIK3CB LOC105515285 LOC105515285 VEGFA VEGFA TP53 TP53 LOC105512042 LOC105512042 ENSCANP00000028447 ENSCANP00000028447 TXN TXN AKT3 AKT3 TXNDC8 TXNDC8 CALML4 CALML4 ACVR2B ACVR2B PRKAA2 PRKAA2 MGST1 MGST1 LOC105521231 LOC105521231 MAP3K5 MAP3K5 MAP2K5 MAP2K5 IL1R2 IL1R2 LOC105513719 LOC105513719 ACTL8 ACTL8 CALM2 CALM2 NFKB1 NFKB1 ENSCANP00000024192 ENSCANP00000024192 ITGB3 ITGB3 ENSCANP00000023686 ENSCANP00000023686 MEF2A MEF2A CYBA CYBA LOC105501334 LOC105501334 MAP2K4 MAP2K4 TNF TNF AKT2 AKT2 PIK3R1 PIK3R1 ENSCANP00000021569 ENSCANP00000021569 LOC105502172 LOC105502172 CDH5 CDH5 PECAM1 PECAM1 ENSCANP00000020642 ENSCANP00000020642 ENSCANP00000020568 ENSCANP00000020568 MAPK8 MAPK8 LOC105515531 LOC105515531 LOC105524240 LOC105524240 FOS FOS MAPK10 MAPK10 ENSCANP00000018854 ENSCANP00000018854 LOC105523325 LOC105523325 GSTA4 GSTA4 ENSCANP00000017605 ENSCANP00000017605 GPC1 GPC1 PIK3CA PIK3CA ENSCANP00000015955 ENSCANP00000015955 PDGFB PDGFB SUMO1 SUMO1 ENSCANP00000015161 ENSCANP00000015161 RAC2 RAC2 CALM3 CALM3 NOS3 NOS3 AKT1 AKT1 NFE2L2 NFE2L2 IFNG IFNG LOC105521593 LOC105521593 GSTA5 GSTA5 IL1R1 IL1R1 CALML6 CALML6 BMP4 BMP4 MAPK12 MAPK12 BMPR1A BMPR1A ENSCANP00000013074 ENSCANP00000013074 ACVR1 ACVR1 ENSCANP00000012397 ENSCANP00000012397 PRKCZ PRKCZ CTNNB1 CTNNB1 ENSCANP00000011556 ENSCANP00000011556 PRKAA1 PRKAA1 ENSCANP00000011255 ENSCANP00000011255 PIAS4 PIAS4 IKBKB IKBKB MAPK9 MAPK9 GSTA3 GSTA3 PLAT PLAT CAV2 CAV2 ENSCANP00000009406 ENSCANP00000009406 RHOC RHOC CAV1 CAV1 ENSCANP00000008647 ENSCANP00000008647 NCF2 NCF2 HSP90AA1 HSP90AA1 BMPR1B BMPR1B RHOA RHOA ASS1 ASS1 SDC1 SDC1 LOC105515605 LOC105515605 MAP2K6 MAP2K6 ENSCANP00000006830 ENSCANP00000006830 MEF2C MEF2C SELE SELE CCL2 CCL2 MGST3 MGST3 LOC105516058 LOC105516058 NOX1 NOX1 PDGFA PDGFA ACVR2A ACVR2A MAPK7 MAPK7 ENSCANP00000005382 ENSCANP00000005382 CHUK CHUK SUMO2 SUMO2 ENSCANP00000005159 ENSCANP00000005159 MAP3K7 MAP3K7 BCL2 BCL2 TRPV4 TRPV4 ENSCANP00000003833 ENSCANP00000003833 CALML3 CALML3 GSTO1 GSTO1 CALM1 CALM1 GSTA2 GSTA2 CAV3 CAV3 GSTM3 GSTM3 ENSCANP00000002057 ENSCANP00000002057 MAP2K7 MAP2K7 PTTG1IP PTTG1IP ITGAV ITGAV NOXA1 NOXA1 MAPK11 MAPK11 ENSCANP00000001410 ENSCANP00000001410 ENSCANP00000001395 ENSCANP00000001395 ACTL7A ACTL7A LOC105503376 LOC105503376 ACTL7B ACTL7B EDN1 EDN1 GSTA1 GSTA1 RAC1 RAC1 GSTM4 GSTM4 ENSCANP00000000051 ENSCANP00000000051 PIK3R3 PIK3R3 ENSCANP00000035672 ENSCANP00000035672 TNFRSF1A TNFRSF1A IKBKG IKBKG GSTO2 GSTO2 PIK3CD PIK3CD PTK2 PTK2 KEAP1 KEAP1 ENSCANP00000038566 ENSCANP00000038566 POTEE POTEE ENSCANP00000038703 ENSCANP00000038703 ITGA2B ITGA2B MAPK14 MAPK14 SDC2 SDC2 GSTP1 GSTP1 SRC SRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105509062Uncharacterized protein. (647 aa)
LOC105525270Uncharacterized protein. (240 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (271 aa)
TXN2Thioredoxin 2. (166 aa)
HSP90B1Heat shock protein 90 beta family member 1. (804 aa)
LOC105525271Uncharacterized protein; Belongs to the GST superfamily. (241 aa)
MGST2Microsomal glutathione S-transferase 2. (94 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
GSTT2BUncharacterized protein; Belongs to the GST superfamily. (244 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
ACTG1Uncharacterized protein. (376 aa)
MAPK13Mitogen-activated protein kinase. (491 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
NPPCNatriuretic peptide C. (126 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
ENSCANP00000032715Uncharacterized protein. (321 aa)
SQSTM1Sequestosome 1. (440 aa)
CTSLCathepsin L; Belongs to the peptidase C1 family. (333 aa)
PIK3R2Uncharacterized protein. (601 aa)
BMPR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1030 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1000 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (246 aa)
ICAM1Intercellular adhesion molecule 1. (532 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
LOC105514391Uncharacterized protein. (190 aa)
LOC105522998Uncharacterized protein. (693 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
LOC105515285HATPase_c domain-containing protein. (711 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (412 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa)
LOC105512042ANK_REP_REGION domain-containing protein; Belongs to the actin family. (796 aa)
ENSCANP00000028447Uncharacterized protein; Belongs to the calmodulin family. (173 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
TXNDC8Thioredoxin domain containing 8. (127 aa)
CALML4Calmodulin like 4. (192 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (750 aa)
PRKAA2Non-specific serine/threonine protein kinase. (545 aa)
MGST1Uncharacterized protein. (155 aa)
LOC105521231Uncharacterized protein; Belongs to the actin family. (376 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1364 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
IL1R2Interleukin 1 receptor type 2. (397 aa)
LOC105513719Uncharacterized protein. (85 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
CALM2Calmodulin 2. (149 aa)
NFKB1Nuclear factor kappa B subunit 1. (970 aa)
ENSCANP00000024192HATPase_c domain-containing protein. (669 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
ENSCANP00000023686GST N-terminal domain-containing protein. (67 aa)
MEF2AMyocyte enhancer factor 2A. (512 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa)
LOC105501334Thioredoxin; Belongs to the thioredoxin family. (101 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (373 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (478 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSCANP00000021569Small ubiquitin-related modifier. (106 aa)
LOC105502172Rad60-SLD domain-containing protein. (72 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (717 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (646 aa)
ENSCANP00000020642Uncharacterized protein. (121 aa)
ENSCANP00000020568Uncharacterized protein. (455 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
LOC105515531HATPase_c domain-containing protein. (644 aa)
LOC105524240Uncharacterized protein. (370 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
ENSCANP00000018854Uncharacterized protein; Belongs to the actin family. (349 aa)
LOC105523325Uncharacterized protein. (284 aa)
GSTA4Glutathione S-transferase alpha 4; Belongs to the GST superfamily. (222 aa)
ENSCANP00000017605Uncharacterized protein; Belongs to the actin family. (163 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (508 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSCANP00000015955Ubiquitin-like domain-containing protein. (115 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (220 aa)
SUMO1Small ubiquitin like modifier 1. (120 aa)
ENSCANP00000015161Rad60-SLD domain-containing protein. (94 aa)
RAC2Rac family small GTPase 2. (192 aa)
CALM3Calmodulin 3. (149 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (601 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
LOC105521593Uncharacterized protein. (181 aa)
GSTA5Glutathione S-transferase alpha 5; Belongs to the GST superfamily. (208 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
CALML6Calmodulin like 6. (181 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
MAPK12Mitogen-activated protein kinase. (325 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ENSCANP00000013074Uncharacterized protein; Belongs to the actin family. (156 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ENSCANP00000012397Small ubiquitin-related modifier. (89 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (392 aa)
CTNNB1Catenin beta 1. (781 aa)
ENSCANP00000011556Small ubiquitin-related modifier. (73 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
ENSCANP00000011255Glutathione S-transferase. (220 aa)
PIAS4Protein inhibitor of activated STAT 4. (510 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
MAPK9Mitogen-activated protein kinase. (399 aa)
GSTA3Glutathione S-transferase alpha 3; Belongs to the GST superfamily. (222 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
ENSCANP00000009406Uncharacterized protein; Belongs to the calmodulin family. (163 aa)
RHOCRas homolog family member C. (193 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (179 aa)
ENSCANP00000008647Uncharacterized protein; Belongs to the actin family. (146 aa)
NCF2Neutrophil cytosolic factor 2. (498 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (821 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
RHOARas homolog family member A. (193 aa)
ASS1Argininosuccinate synthase 1. (391 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (288 aa)
LOC105515605Uncharacterized protein; Belongs to the GST superfamily. (229 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
ENSCANP00000006830Protein kinase domain-containing protein. (373 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
SELESelectin E. (612 aa)
CCL2C-C motif chemokine. (99 aa)
MGST3Microsomal glutathione S-transferase 3. (166 aa)
LOC105516058Glutathione S-transferase. (237 aa)
NOX1NADPH oxidase 1. (522 aa)
PDGFAPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (307 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
ENSCANP00000005382Thioredoxin domain-containing protein. (185 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
SUMO2Small ubiquitin-related modifier. (88 aa)
ENSCANP00000005159Ubiquitin-like domain-containing protein. (129 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
ENSCANP00000003833Small ubiquitin-related modifier. (74 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
GSTO1Uncharacterized protein. (241 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
GSTA2Glutathione S-transferase alpha 2; Belongs to the GST superfamily. (222 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
GSTM3Glutathione S-transferase. (225 aa)
ENSCANP00000002057Uncharacterized protein. (147 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (468 aa)
PTTG1IPPTTG1 interacting protein. (159 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
NOXA1NADPH oxidase activator 1. (424 aa)
MAPK11Mitogen-activated protein kinase. (306 aa)
ENSCANP00000001410Uncharacterized protein. (155 aa)
ENSCANP00000001395Uncharacterized protein. (61 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
LOC105503376Thioredoxin domain-containing protein. (104 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
EDN1Endothelin 1. (211 aa)
GSTA1Glutathione S-transferase. (193 aa)
RAC1Uncharacterized protein. (205 aa)
GSTM4Glutathione S-transferase mu 4; Belongs to the GST superfamily. (218 aa)
ENSCANP00000000051Ubiquitin-like domain-containing protein. (62 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
ENSCANP00000035672Glutathione S-transferase. (216 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (369 aa)
GSTO2Glutathione S-transferase omega 2. (215 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1071 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
KEAP1Kelch like ECH associated protein 1. (624 aa)
ENSCANP00000038566Uncharacterized protein. (400 aa)
POTEEANK_REP_REGION domain-containing protein; Belongs to the actin family. (952 aa)
ENSCANP00000038703Uncharacterized protein. (89 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1039 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
GSTP1Uncharacterized protein; Belongs to the GST superfamily. (210 aa)
SRCTyrosine-protein kinase. (458 aa)
Your Current Organism:
Colobus angolensis
NCBI taxonomy Id: 336983
Other names: C. angolensis palliatus, Colobus angolensis palliatus
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