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| | KTR06528.1 | NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa) |
| | KTR11828.1 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (183 aa) |
| | KTR11852.1 | Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa) |
| | KTR11830.1 | Diguanylate cyclase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (135 aa) |
| | KTR11854.1 | N-acetylglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. (180 aa) |
| | ubiA | UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa) |
| | KTR11733.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa) |
| | KTR11746.1 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa) |
| | KTR11545.1 | 3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa) |
| | KTR11217.1 | 1,4-dihydroxy-2-naphthoate prenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiA prenyltransferase family. (293 aa) |
| | KTR11072.1 | Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (445 aa) |
| | KTR11076.1 | UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa) |
| | KTR11077.1 | Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa) |
| | KTR10934.1 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa) |
| | KTR10913.1 | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (312 aa) |
| | KTR10743.1 | 5'-methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (280 aa) |
| | KTR10387.1 | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa) |
| | KTR10395.1 | FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (406 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (349 aa) |
| | KTR10151.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa) |
| | KTR09997.1 | NADPH:quinone dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa) |
| | KTR10000.1 | Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (310 aa) |
| | KTR09781.1 | Aldehyde oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa) |
| | KTR09799.1 | Hypothetical protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (223 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (421 aa) |
| | KTR09791.1 | Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa) |
| | KTR09694.1 | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa) |
| | KTR09523.1 | NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa) |
| | KTR09539.1 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa) |
| | KTR09541.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa) |
| | KTR09444.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa) |
| | KTR09383.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (604 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (626 aa) |
| | KTR09354.1 | 3-demethylubiquinone-9 3-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa) |
| | acpS | Hypothetical protein; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (125 aa) |
| | KTR09181.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa) |
| | KTR09207.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa) |
| | KTR09186.1 | ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa) |
| | fabH | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (329 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (82 aa) |
| | KTR09188.1 | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (414 aa) |
| | KTR09194.1 | 2-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa) |
| | KTR09131.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa) |
| | KTR09072.1 | Triosephosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa) |
| | KTR09086.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (476 aa) |
| | KTR08985.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (421 aa) |
| | proB | Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (263 aa) |
| | KTR09026.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa) |
| | KTR08941.1 | 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (641 aa) |
| | KTR08963.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa) |
| | KTR08959.1 | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa) |
| | KTR08799.1 | Gluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa) |
| | KTR08868.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (159 aa) |
| | KTR08714.1 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (150 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (423 aa) |
| | KTR08738.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa) |
| | hisC | Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (374 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (296 aa) |
| | KTR08655.1 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (180 aa) |
| | KTR08658.1 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (248 aa) |
| | KTR08672.1 | 2,5-diketo-D-gluconic acid reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa) |
| | KTR08678.1 | Branched-chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa) |
| | KTR08621.1 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (207 aa) |
| | KTR08366.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa) |
| | KTR08218.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa) |
| | KTR08152.1 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa) |
| | thrB | Serine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (308 aa) |
| | KTR08081.1 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (359 aa) |
| | KTR08082.1 | Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (494 aa) |
| | KTR07966.1 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa) |
| | acpS-2 | 4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (124 aa) |
| | KTR07750.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa) |
| | KTR07550.1 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. (437 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (564 aa) |
| | KTR07403.1 | Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (607 aa) |
| | KTR07404.1 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (341 aa) |
| | KTR07408.1 | 3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (355 aa) |
| | KTR07410.1 | Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa) |
| | KTR07210.1 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa) |
| | KTR07234.1 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (446 aa) |
| | KTR07128.1 | Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa) |
| | KTR07119.1 | Deaminase/reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa) |
| | KTR07124.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa) |
| | KTR06998.1 | Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa) |
| | KTR06999.1 | Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (347 aa) |
| | KTR06861.1 | 4-hydroxybenzoyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa) |
| | KTR06677.1 | NADPH:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa) |
| | KTR06483.1 | Catalyzes the conversion of shikimate to 3-dehydroshikimate; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa) |
| | KTR06484.1 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (461 aa) |
| | KTR06496.1 | Glyoxalase/bleomycin resistance protein/dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa) |
| | KTR06511.1 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (312 aa) |
| | KTR06512.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (591 aa) |
| | KTR06416.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa) |
| | hisD-2 | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa) |
| | KTR06423.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (894 aa) |
| | KTR06427.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa) |
| | KTR06245.1 | Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa) |
| | KTR06076.1 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (461 aa) |
| | KTR06079.1 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1136 aa) |
| | KTR05882.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family. (147 aa) |
| | menG | Ubiquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (269 aa) |
| | menD | Hypothetical protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (563 aa) |
| | menA | 1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (332 aa) |
| | menB | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (309 aa) |
| | menC | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (328 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (350 aa) |
| | KTR05643.1 | Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (421 aa) |
| | KTR05354.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa) |
| | KTR05230.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa) |
| | argH | Argininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa) |
| | argG | Argininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (398 aa) |
| | KTR04854.1 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (317 aa) |
| | KTR04865.1 | Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (344 aa) |
| | argJ | N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (372 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (365 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (307 aa) |
| | gpmA | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa) |
| | KTR04669.1 | Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (321 aa) |
| | KTR04648.1 | Succinyl-diaminopimelate desuccinylase; Catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa) |
| | KTR04674.1 | GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa) |
| | rocD | Ornithine--oxo-acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (409 aa) |
| | KTR04526.1 | Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa) |
| | KTR04467.1 | Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (532 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (259 aa) |
| | metXA | Homoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (399 aa) |
| | KTR04367.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa) |
| | KTR04388.1 | Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa) |
| | KTR04125.1 | CysJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (595 aa) |
| | KTR04142.1 | NADPH:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa) |
| | KTR04042.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (911 aa) |
| | KTR04000.1 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa) |
| | KTR04004.1 | UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (257 aa) |
| | KTR03962.1 | Amino acid adenylation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1323 aa) |
| | KTR03946.1 | Deaminase/reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa) |
| | KTR03818.1 | Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa) |
| | trpE | Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (509 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (127 aa) |
| | hisF | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (279 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa) |
| | kbl | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (394 aa) |
| | carB | Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1092 aa) |
| | carA | Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (399 aa) |
| | KTR03826.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (360 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (186 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (406 aa) |
| | KTR03799.1 | Riboflavin kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (320 aa) |
| | KTR03455.1 | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the aconitase/IPM isomerase family. (461 aa) |
| | leuD | Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (198 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (331 aa) |
| | lipA | Radical SAM protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (327 aa) |
| | KTR03365.1 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa) |
| | KTR03384.1 | methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa) |
| | KTR03386.1 | UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa) |
| | pgi | Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (568 aa) |
| | KTR03117.1 | Hypothetical protein; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ). Belongs to the Thz kinase family. (274 aa) |
| | thiE | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (227 aa) |
| | KTR03118.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa) |
| | KTR03129.1 | NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa) |
| | pdxT | Glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (201 aa) |
| | pdxS | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (306 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (180 aa) |
| | KTR02589.1 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa) |
| | KTR02590.1 | Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa) |
| | KTR02566.1 | Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa) |
| | KTR02514.1 | 3-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. FabH family. (322 aa) |
| | KTR02484.1 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (372 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (276 aa) |
| | ribA | GTP cyclohydrolase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (218 aa) |
| | KTR02446.1 | DeoR faimly transcriptional regulator; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (344 aa) |
| | KTR02418.1 | Histidinol phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa) |
| | aroA-2 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (467 aa) |
| | KTR02331.1 | 2,5-diketo-D-gluconic acid reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa) |
| | KTR02332.1 | Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (646 aa) |
| | KTR02170.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa) |
| | KTR02113.1 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1535 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (266 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (404 aa) |
| | KTR02091.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa) |
| | glpX | Type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa) |
| | gltD | Glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa) |
